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Absorption of paraquat by rat gut in vitro

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Abstract

The absorption of radioactively labeled paraquat was measured in rat ileum, jejunum and colon by a micro everted sac technique (Semenza and Mühlhaupt, 1969). The absorption rate increased linearly over the range of concentrations measured (10−5 to 10−2 M) and was enhanced by nearly 50% in the absence of sodium ions. The absorption rate decreased in the order: ileum, jejunum, colon whereby in the colon still 65% of the values of the small intestine were observed.

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Steffen, C., Konder, H. Absorption of paraquat by rat gut in vitro. Arch Toxicol 43, 99–103 (1979). https://doi.org/10.1007/BF00333616

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