Summary
In the present paper an intercalary deletion of band 8q23 is reported in another patient with Langer-Giedion syndrome. These data confirm that the deletion in 8q responsible for this malformation syndrome is located at band 8q23.
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Bühler EM, Bühler UK, Stalder GR, Jani L, Jurik LP (1980) Chromosome deletion and multiple cartilagenous exostoses. Eur J Pediatr 133:163–166
Fryns JP, Logghe N, Van Eygen M, Van den Berghe H (1979) Interstitial deletion of the long arm of chromosome 8 karyotype: 46,XY,del(8)(q21). Hum Genet 48:127–130
Fryns JP, Logghe N, Van Eygen M, Van den Berghe H (1981) Langer-Giedion syndrome and deletion of the long arm of chromosome 8. Hum Genet 58:231–232
Hall BD, Langer LO, Giedion A, Smith DW, Cohen MM, Beals RK, Brandner M (1974) Langer-Giedion syndrome. Birth Defects 10: 147–164
Pfeiffer RA (1980) Langer-Giedion syndrome and additional congenital malformations with interstitial deletion of the long arm of chromosome 8, 46,XY,del8(q13-22). Clin Genet 18:142–146
Stoltzfus E, Ladda RL, Lloyd-Still J (1977) Langer-Giedion syndrome type II, TRP. J Pediatr 91:277–280
Turleau C, Chavin-Colin F, de Grouchy J, Maroteaux P, Rivera H (1983) Langer-Giedion syndrome with and without del 8q. Assignment of critical segment to 8q23. Hum Genet 62:183–187
Zabel BU, Baumann VA (1982) Langer-Giedion syndrome with interstitial 8q- deletion. Am J Med Genet 11:353–358
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Fryns, J.P., Heremans, G., Marien, J. et al. Langer-Giedion syndrome and deletion of the long arm of chromosome 8. Confirmation of the critical segment to 8q23. Hum Genet 64, 194–195 (1983). https://doi.org/10.1007/BF00327126
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DOI: https://doi.org/10.1007/BF00327126