Summary
Chromosome in situ hybridization studies locate c-mos to chromosome band 8q11 in leukemic cells carrying the t(8;21) (q22;q22). This amends the previous assignment of c-mos to chromosome band 8q22 and conforms with its recent assignment to 8q11 in normal cells and in a cell line with a structurally abnormal chromosome 8. C-mos lies proximally to, and distant from, the breakpoint at 8q22 in the t(8;21) and is unlikely to have a role in the onset of acute myeloid leukemia characterized by this translocation.
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Morris, C.M., Bowen, J. & Fitzgerald, P.H. Localization of human c-mos to chromosome band 8q11 in leukemic cells with the t(8;21) (q22;q22). Hum Genet 81, 339–342 (1989). https://doi.org/10.1007/BF00283687
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DOI: https://doi.org/10.1007/BF00283687