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Cytogenetic localisation of the purine 1 and guanosine 1 loci of Drosophila melanogaster; the purine 1 locus specifies a vital function

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Summary

Three auxotrophic mutants at two loci (pur 1 and gua 1) apparently involved in purine metabolism were mapped cytologically to region 9E1-9E3 on the X-chromosome of Drosophila. Because mutants of pur 1 behaved as semi-lethals against deficiencies even on permissive medium, it appears that the pur 1 locus is vital to the fly and its auxotrophic mutants are hypomorphs.

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Authors and Affiliations

  1. Department of Genetics, University of Alberta, T6G 2E9, Edmonton, Alberta, Canada

    Merrie M. Johnson, E. P. Woloshyn & David Nash

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  1. Merrie M. Johnson
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  2. E. P. Woloshyn
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  3. David Nash
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Communicated by W. Gehring

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Johnson, M.M., Woloshyn, E.P. & Nash, D. Cytogenetic localisation of the purine 1 and guanosine 1 loci of Drosophila melanogaster; the purine 1 locus specifies a vital function. Molec. Gen. Genet. 174, 287–292 (1979). https://doi.org/10.1007/BF00267801

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  • DOI: https://doi.org/10.1007/BF00267801

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