Abstract
Changes in peak time and amplitude of the direct current registered c-wave of the electroretinogram of the albino rabbit were investigated with various stimuli of duration ranging from 0.25 to 10 sec. The stimulus intensity was 500 lux at the surface of the cornea. Slow PIII was isolated by administrations of sodium iodate and sodium aspartate.
The peak time of the c-wave was longer than that of the slow PIII in the range of stimulus duration less than 3.5 sec, but peak times were almost the same in the range above 3.5 sec. The amplitude of the c-wave at peak was larger than the corresponding amplitude of the slow PIII in the range less than 1 sec, but the slow PIII became larger than the c-wave at more than 1 sec. For stimuli less than 4 sec, the smaller the stimulus duration, the smaller was the negative slow PIII which affected the height of the c-wave.
We conclude that in order to minimize the influence of the slow PIII on the c-wave, the duration of stimuli with intensity of 500 lux for recording the c-wave of the rabbit should be less than 4 sec.
Similar content being viewed by others
References
Granit R (1933) The component of the retinal action potential in mammals and their relation to the discharge in the optic nerve. J Physiol 77: 207–39.
Lurie M and Marmor MF (1980) Similarities between the c-wave and slow PIII in the rabbit eye. Invest Ophthalmol Vis Sci 19: 1113–7.
Marmor MF, Pockrand P and Lurie M (1979) Experiments toward the development of a clinical c-wave test. Proceedings of the XVIth Symposium of the International Society for Clinical Electrophysiology of Vision, ed: Tazawa Y: 107–11.
Oakley IB and Green DG (1976) Correlation of light-induced changes in retinal extracellular potassium concentration with c-wave of the electroretinogram. J Neurophysiol 39: 1117–33.
Tomita T (1982) The recent basic study on ERG. Ganka 24: 953–61.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yoshimura, Y., Onoe, S., Takahashi, Y. et al. Electroretinogram c-wave and slow PIII of the rabbit: Changes in peak time and amplitude under various stimulus durations. Doc Ophthalmol 69, 187–193 (1988). https://doi.org/10.1007/BF00153700
Issue Date:
DOI: https://doi.org/10.1007/BF00153700