Skip to main content
Log in

Le syndrome de pseudo-Bartter néonatal dû à des désordres alimentaires maternels: peut-être plus fréquent qu’il n’y paraît

Neonatal pseudo-Bartter syndrome due to maternal eating disorders: maybe more frequent than expected

  • Article Original / Original Article
  • Published:
Revue de médecine périnatale

Résumé

Le syndrome de pseudo-Bartter, caractérisé par une alcalose hypochlorémique-hypokaliémique, mime les anomalies biochimiques du syndrome de Bartter sans atteinte rénale primaire. Il peut survenir suite à des vomissements chroniques au cours de la grossesse liés à des désordres psychiatriques. Il peut affecter aussi le foetus. L’absence de symptômes maternels due à l’installation lente des anomalies biochimiques au cours de la grossesse pourrait faire sousestimer de sérieux désordres électrolytiques présents chez la mère et son enfant à la naissance. Deux situations de cet ordre sont décrites où le diagnostic a été posé chez le nouveau-né et, a posteriori, chez sa mère. Les obstétriciens doivent rester attentifs aux signes de désordre alimentaire de leur patiente qui les minimise souvent.

Abstract

Pseudo-Bartter Syndrome is defined by a hypochloremic-hypokaliemic metabolic alkalosis but without primary tubular renal defects. This metabolic imbalance can result from a state of often hidden chronic vomiting in some psychiatric disorders. It can affect both the pregnant mother and her foetus. Owing to the paucity of symptoms due to the slow installation of these biochemical disturbances, a diagnosis of pseudo-Bartter syndrome could be missed at birth in the mother and her infant. This potential misdiagnosis could expose the mother and her baby to serious complications during the first hours of life. We report on two cases of neonatal pseudo-Bartter in which the diagnosis was made a posteriori in the mothers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Références

  1. Bartter FC, Pronove P, Gill JR Jr, et al (1962) Hyperplasia of juxtaglomerular complex with hyperaldosteronism and hypokaliemic alkalosis. Am J Med 33: 811–828

    Article  PubMed  CAS  Google Scholar 

  2. Proesman W (2006) Threading through the mizmaze of Bartter syndrome. Pediatr Nephrol 21:896–902

    Article  Google Scholar 

  3. Watanabe S, Fukumoto S, Chang H, et al (2002) Association between activating mutations of calcium-sensing receptor and Bartter’s syndrome. Lancet 360:692–694

    Article  PubMed  CAS  Google Scholar 

  4. Vanhaesebrouck S, Allegaert K, Vanhole C, et al (2003) Pseudo-Bartter syndrome in a neonate on prostaglandin infusion. Eur J Pediatr 162: 569–571

    Article  PubMed  Google Scholar 

  5. Langhendries JP, Thiry V, Bodart E, et al (1989) Exogenous prostaglandin administration and pseudoBartter syndrome. Eur J Pediatr 149:208–209.

    Article  PubMed  CAS  Google Scholar 

  6. Jamison RL, Ross JC, Kempson RL et al (1982) Surreptitious diuretic ingestion and pseudo-Bartter’s Syndrome. Am J Med 73(1):142–147

    Article  PubMed  CAS  Google Scholar 

  7. Sola F, André JL (1999) Pseudo-Bartter syndrome induced by incontrollable vomiting. Arch Pediatr 6(4):481–483

    Article  PubMed  CAS  Google Scholar 

  8. Higuchi R, Sugimoto T, Hiramatsu C, et al (2008) Neonatal pseudo-bartter syndrome due to maternal eating disorder. J Perinatol 28:646–648

    Article  PubMed  CAS  Google Scholar 

  9. Veizis IE, Cotton CU (2007) Role of kidney chloride channels in health and disease. Pediatr Nephrol 22(6):770–777

    Article  PubMed  Google Scholar 

  10. Amirlak I, Dawson KP (2000) Bartter syndrome: an overview. Q J Med 93:207–215

    Article  CAS  Google Scholar 

  11. Franko DL, Blais MA, Becker AE, et al (2001) Pregnancy complications and neonatal outcomes in women with eating disorders. Am J Pscyhiatry 158:1461–1466

    Article  CAS  Google Scholar 

  12. Velazquez H, Ellison DH, Wright FS (1987) Chloride-dependent potassium secretion in early and late renal distal tubules. Am J Physiol 253:F555–562

    PubMed  CAS  Google Scholar 

  13. Velazquez H, Ellison DH, Wright FS (1992) Luminal influences on potassium secretion: chloride, sodium and thiazide diuretic. Am J Physiol 262:F1076–1082

    PubMed  CAS  Google Scholar 

  14. Muto S (2001) Potassium transport in the mammalian collecting duct. Physiol Rev 81: 85–116

    PubMed  CAS  Google Scholar 

  15. Reilly RF, Ellison DN (2000) Mammalian Distal tubule: physiology, pathophysiology and molecular anatomy. Physiol Rev 80:277–313

    PubMed  CAS  Google Scholar 

  16. Amorim JBO, Bailey MA, Musa-Aziz R, et al (2003) Role of luminal anion and pH in distal tubule potassium secretion. Am J Physiol 284:F381–388

    CAS  Google Scholar 

  17. Voyame J, Terrier P, Guignard JP, et al (1999) Transient hypokaliemic metabolic alkalosis in a newborn mimicking Bartter’s syndrome. J Pediatr 134:794

    Article  PubMed  CAS  Google Scholar 

  18. Mathot M, Maton P, Henrion H, et al (2006) Pseudo-Bartter syndrome in a pregnant mother and her fetus. Pediatr Nephrol 21(7):1037–1040

    Article  PubMed  Google Scholar 

  19. Stulc J, Stulcova B, Husain S, et al (1996) Transfer of Cl- across placenta of anesthtized rat. Am J Physiol 271: R 1107–1114

    CAS  Google Scholar 

  20. Stulc J (1997) Placental transfer of inorganic ions and water. Physiol Rev 77:805–836

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to J. -P. Langhendries.

About this article

Cite this article

Gobert, C., Maton, P., François-Adant, A. et al. Le syndrome de pseudo-Bartter néonatal dû à des désordres alimentaires maternels: peut-être plus fréquent qu’il n’y paraît. Rev. med. perinat. 4, 17–22 (2012). https://doi.org/10.1007/s12611-012-0170-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12611-012-0170-z

Mots clés

Keywords

Navigation