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Imaging of atherosclerosis

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Abstract

Cardiovascular disease (CVD) is a major health concern worldwide and atherosclerosis is the main cause of CVD. Atherosclerosis is a systemic and chronic inflammatory disease, which is characterized by plaque formation and can affect different vascular beds. Imaging of atherosclerosis could guide therapeutic interventions. Ultrasound, computed tomography, magnetic resonance imaging (MRI), positron emission tomography (PET) and interventional angiography are the main imaging modalities available for the assessment of atherosclerotic burden and for potential prediction of future events. In addition, the introduction of new hybrid imaging techniques like PET/MRI allow for the simultaneous evaluation of anatomical and metabolic characteristics tissues. This article provides an overview of coronary and non-coronary atherosclerosis and summarizes the current understanding of different available imaging techniques. The integration of these techniques in clinical practice may allow for superior risk stratification and therapeutic planning as well as monitoring of interventional and medication based treatment strategies.

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Authors and Affiliations

  1. Cardiac MR PET CT Program, Harvard Medical School, Massachusetts General Hospital, 165 Cambridge Street, Suite 400, Boston, MA, 02114-2750, USA

    Richard A. P. Takx & Brian B. Ghoshhajra

  2. Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands

    Richard A. P. Takx

  3. University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA

    Sasan Partovi

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  1. Richard A. P. Takx
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Correspondence to Brian B. Ghoshhajra.

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Takx, R.A.P., Partovi, S. & Ghoshhajra, B.B. Imaging of atherosclerosis. Int J Cardiovasc Imaging 32, 5–12 (2016). https://doi.org/10.1007/s10554-015-0730-y

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