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Regulator of energy metabolism protects the myocardium during pathological processes

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Abstract

Normalizing effect of energy metabolism regulator (succinic acid) on mitochondrial processes in rat myocardium during hypoxia, cardiac arrhythmia, and salicylate treatment was experimentally shown. A new alternative method for myocardial protection is proposed and its high efficiency in heart diseases of hypoxic and ischemic origin is validated.

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Authors and Affiliations

  1. Laboratory of Molecular Pharmacology with Pharmacokinetics Group, Institute of Pharmacology, Tomsk Research Center, Siberian Division of Russian Academy of Medical Sciences, Russia

    V. A. Khazanov, K. Yu. Vasil’ev, O. S. Bryushinina, A. A. Kiseleva & R. V. Gurto

Authors
  1. V. A. Khazanov
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  2. K. Yu. Vasil’ev
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  3. O. S. Bryushinina
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  4. A. A. Kiseleva
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  5. R. V. Gurto
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Correspondence to V. A. Khazanov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Supplement 1, pp. 35–40, January, 2007

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Khazanov, V.A., Vasil’ev, K.Y., Bryushinina, O.S. et al. Regulator of energy metabolism protects the myocardium during pathological processes. Bull Exp Biol Med 143 (Suppl 1), 28–33 (2007). https://doi.org/10.1007/s10517-007-0075-1

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  • DOI: https://doi.org/10.1007/s10517-007-0075-1

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