Prevalence of fibromyalgia in general population and patients, a systematic review and meta-analysis

  • Fatemeh Heidari
  • Mahdi Afshari
  • Mahmood Moosazadeh
Epidemiology of RMD

DOI: 10.1007/s00296-017-3725-2

Cite this article as:
Heidari, F., Afshari, M. & Moosazadeh, M. Rheumatol Int (2017). doi:10.1007/s00296-017-3725-2


This study aims to estimate the reliable prevalence of fibromyalgia using meta-analysis method. Available databanks were searched using appropriate keywords. According to the heterogeneity between the results (indicated by Cochrane and I square indices), random- or fixed-effects model was applied to combine the point prevalences. Meta-regression models were used to assess the suspected factors in the heterogeneity. In 65 selected papers, 81 evidences regarding prevalence of fibromyalgia among 3,609,810 subjects from general population and specific groups were investigated. The total prevalences (95% confidence intervals) of fibromyalgia among general population, women, men, patients referring to rheumatology and internal departments, patients with Irritable bowel syndrome (IBS), hemodialysis patients and those with type 2 diabetes mellitus were estimated as of 1.78% (1.65, 1.92), 3.98% (2.80, 5.20), 0.01% (−0.04, 0.06), 15.2% (13.6, 16.90), 12.9% (12.70, 13.10), 6.30% (4.60, 7.90) and 14.80% (11.10, 18.40), respectively. In addition, prevalence of fibromyalgia in specified groups varied from 3.90% in hemodialysis patients to 80% in patients suffering from Behcet syndrome. This meta-analysis showed that prevalence of fibromyalgia in general population was significantly lower than that in populations with some diseases.


Fibromyalgia Prevalence Meta-analysis Systematic review 

Supplementary material

296_2017_3725_MOESM1_ESM.doc (33 kb)
Supplementary material 1 (DOC 33 kb)

Copyright information

© Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Student Research Committee, School of Nursing and MidwiferyMazandaran University of Medical SciencesSariIran
  2. 2.Department of Community MedicineZabol University of Medical SciencesZabolIran
  3. 3.Health Sciences Research Center, Addiction InstituteMazandaran University of Medical SciencesSariIran

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