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Biocompatible ultrananocrystalline diamond coatings for implantable medical devices

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Abstract

A novel multifunctional and biocompatible ultrananocrystalline diamond (UNCD) film technology developed recently represents a new material with a unique combination of functionalities, including biocompatibility, to enable a new generation of implantable medical devices and scaffolds for tissue engineering. Following a description of the synthesis and properties of UNCD films and a comparison with other diamond film technologies, this article focuses on descriptions of key UNCD-based medical devices to treat specific medical conditions requiring effective therapies: (1) A UNCD-coated microchip (artificial retina) implantable inside the eye on the retina to restore partial vision to people blinded by retinitis pigmentosa and macular degeneration produced by genetically induced degeneration of the retina photoreceptors. (2) A UNCD-coated intraocular device for treatment of glaucoma in the eye. (3) UNCD-coated metal dental implants with potential order of magnitude longer life and superior performance than current implants.

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References

  1. O. Auciello, A.V. Sumant, Diam. Relat. Mater. 19, 699 (2010).

    Google Scholar 

  2. J.E. Butler, A.V. Sumant, Chem. Vap. Depos. 14 (7–8), 145 (2008).

    Google Scholar 

  3. S. Rotter, in Proc. Conf. Applied Diamond Conference/Frontier Carbon Technologies- ADC/FCT ’99, M. Yoshikawa, Y. Koga, Y. Tzeng, C.P. Klages, K. Miyoshi, Eds. (MYU, K.K, Tokyo, 1999), p. 25.

    Google Scholar 

  4. N. Naguib, J. Birrell, J. Elam, J.A. Carlisle, O. Auciello, US Patent 7,128,889 (2006).

    Google Scholar 

  5. M. Sternberg, P. Zapol, L.A. Curtiss, Phys. Rev. B 68, 205330 (2003).

    Google Scholar 

  6. P.P.W. May, N.L. Allan, M.N.R. Ashfold, J.C. Richley, Y.A. Mankelevich, J. Phys. Condens. Matter 21, 364203 (2009).

    Google Scholar 

  7. X. Xiao, J. Birrell, J.E. Gerbi, O. Auciello, J.A. Carlisle, J. Appl. Phys. 96, 2232 (2004).

    Google Scholar 

  8. A.V. Sumant, O. Auciello, R.W. Carpick, S. Srinivasan, J.E. Butler, MRS Bull. 35, 1 (2010).

    Google Scholar 

  9. X. Xiao, J. Wang, J.A. Carlisle, B. Mech, R. Greenberg, R. Freda, M.S. Humayun, J. Weiland, O. Auciello, J. Biomed. Mater. 77B (2), 273 (2006).

    Google Scholar 

  10. B.R. Stoner, G.-H. Ma, S.D. Wolter, J.T. Glass, Phys. Rev. B 45, 11067 (1992).

    Google Scholar 

  11. Y.C. Lee, S.J. Lin, C.T. Chia, H.F. Cheng, I.N. Lin, Diam. Relat. Mater. 14, 296 (2005).

    Google Scholar 

  12. Y.C. Chen, X.Y. Zhong, A.R. Konicek, D.S. Grierson, N.H. Tai, I.N. Lin, B. Kabius, J.M. Hiller, A.V. Sumant, R.W. Carpick, O. Auciello, Appl. Phys. Lett. 92, 133113 (2008).

    Google Scholar 

  13. D.J. Garrett, K. Ganesan, A. Stacey, K. Fox, H. Meffin, S. Prawer, J. Neural Eng. 9, 016002 (2012).

    Google Scholar 

  14. J. Zhanga, J.W. Zimmer, R.T. Howe, R. Maboudian, Diam. Relat. Mater. 17 (1), 23 (2008).

    Google Scholar 

  15. B. Shi, Q. Jin, L. Chen, O. Auciello, Diam. Relat. Mater. 18 (2–3), 596 (2009).

    Google Scholar 

  16. W.F. House, Ann. Otol. Rhinol. Laryngol. 85 (Suppl. 27), Pt 2 1 (1976).

    Google Scholar 

  17. J.D. Weiland, W. Liu, M.S. Humayun, Annu. Rev. Biomed. Eng. 7, 361 (2005).

    Google Scholar 

  18. http://www.eurekanetwork.org/project/-/id/5558.

  19. S.S. Lane, B.D. Kuppermann, Curr. Opin. Ophthalmol. 17 (1), 94 (2006).

    Google Scholar 

  20. E. Zrenner, K.U. Bartz-Schmidt, H. Benav, D. Besch, A. Bruckmann, V.P. Gabel, F. Gekeler, U. Greppmaier, A. Harscher, S. Kibbel, J. Koch, A. Kusnyerik, T. Peters, K. Stingl, H. Sachs, A. Stett, P. Szurman, B. Wilhelm, R. Wilke, Proc. R. Soc. London, Ser. B (2010), doi: http://doi.org/10.1098/rspb 1747.

    Google Scholar 

  21. D. Loudin, D.M. Simanovskii, K. Vijayraghavan, C.K. Sramek, A.F. Butterwick, P. Huie, G.Y. McLean, D.V. Palanker, J. Neural Eng. 4 (1), S72 (2007).

    Google Scholar 

  22. S. Ings, The Eye: A Natural History (Bloomsbury, London, 2007), p. 276.

    Google Scholar 

  23. A. Rush, P.R. Troyk, IEEE Trans. Biomed. Eng. 59 (11), 3255 (2012).

    Google Scholar 

  24. Bionic Vision Australia, Annual Report (2013); http://bionicvision.org.au/about/.

  25. P. Doyle, P.R. Troyk, S.K. Kelly, D.B. Shire, J.L. Wyatt, J.F. Rizzo, Invest. Ophthalmol. Vis. Sci. 51, 3032 (2010).

    Google Scholar 

  26. M.S. Humayun, J.D. Dorn, L. da Cruz, G. Dagnelie, J.A. Sahel, P.E. Stanga, A.V. Cideciyan, J.L. Dancan, D. Eliott, E. Filley, A.C. Ho, A. Santos, A.B. Safran, A. Arditi, L.V. Del Priore, R.J. Greenberg, Argus II Study Group, Ophthalmology 119 (4), 779 (2012).

    Google Scholar 

  27. H. Hammerle, K. Kobuch, K. Kohler, W. Nisch, H. Sachs, M. Stelzle, Biomaterials 23, 797 (2002).

    Google Scholar 

  28. J. Meyer, Sens. Actuators, A 97–98, 1 (2001).

    Google Scholar 

  29. F. Stuart, D. Edell, A. Guzelian, Y. Liu, R. Edell, J. Biomed. Mater. Res. A 67, 856 (2003).

    Google Scholar 

  30. J. Seo, S. Kim, H. Chung, H. Kim, H. Yu, Y. Yu, Mater. Sci. Eng. C 24, 185 (2004).

    Google Scholar 

  31. D.D. Zhou, E. Greenbaum, Eds., Implantable Neural Prostheses (Springer, New York, 2010), vols. 1–2.

    Google Scholar 

  32. B. Paolo, F. Di. Matteo, Ophthalmic. Res. 50, 197 (2013).

    Google Scholar 

  33. O. Auciello, P. Gurman, A. Berra, M. Zaravia, R. Zysler, in Diamond Based Materials for Biomedical Applications, Roger Narayan, Ed. (Woodhead, Elsevier, Cambridge, 2013), chap. 6, pp. 151–169.

    Google Scholar 

  34. W. Kenneth Ward, J. Diabetes Sci. Technol. 2 (5), 768 (2008).

    Google Scholar 

  35. K.S. Lim, B.D.S. Allan, A.W. Loyd, A. Muirm, P.T. Khaw, Br. J. Ophthalmol. 82, 1083 (1998).

    Google Scholar 

  36. M. Abdel-Hady Gepreel, M. Niinomi, J. Mech. Behav. Biomed. Mater. 20, 407 (2013).

    Google Scholar 

  37. A.P. Omar, M. Omar, M. Esposito, J. Lausmaa, P. Thomsen, J. R. Soc. Interface 7, S515 (2010).

    Google Scholar 

  38. R.A. Gittens, R. Olivares-Navarrete, R. Tannenbaum, B.D. Boyan, Z. Schwartz, J. Dent. Res. 90 (12), 1389 (2011).

    Google Scholar 

  39. D.G. Olmedo, R.L. Cabrini, G. Duffó, M.B. Guglielmotti, Int. J. Oral Maxillofac. Surg. 37 (11), 1032 (2008).

    Google Scholar 

  40. L.A. Allen, V. Ambardekar, K.M. Devaraj, J.J. Maleszewski, E.E. Wolfel, N. Engl. J. Med. 370 (6), 559 (2014).

    Google Scholar 

  41. S.A. Hacking, P. Boyraz, B.M. Powers, E. Sen-Gupta, W. Kucharski, J. Neurosci. Methods 211 (2), 237 (2012).

    Google Scholar 

  42. M. Amaral, P.S. Gomes, M.A. Lopes, J. Santos, R. Silva, J. Nanomater. 1, 9 (2008).

    Google Scholar 

  43. S. Bhattacharyya, O. Auciello, J. Birrell, J.A. Carlisle, L.A. Curtiss, A.N. Goyette, D.M. Gruen, A.R. Krauss, J. Schlueter, A. Sumant, P. Zapol, Appl. Phys. Lett. 79 (10), 1441 (2001).

    Google Scholar 

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Acknowledgments

Work performed at the University of Texas-Dallas was supported by the Endowed Chair funds of O.A. (#37139010). O.A. acknowledges support by the DOE-Artificial Retina Project (US Department of Energy, Biomedical Engineering Research under contract W-31-109-ENG-38) and collaborators, especially M. Humayun (project director). Work performed in M.G.’s laboratory (University of Buenos Aires-Argentina) was funded by grants: UBACyT 20020100100812 (UBA); PIP 11220090100117 (CONICET); and PDTS PO 01 2013 (UBA)-Ministry of Science, Technology, and Productive Innovation, Argentina. M.G. acknowledges contributions by Dr. Cabrini and Eng. Almagro (CNEA Argentina) for the experimental model for laminar implants.

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Authors and Affiliations

  1. Materials Science and Engineering and Bioengineering Department, The University of Texas at Dallas, USA

    Orlando Auciello

  2. The University of Texas at Dallas and the Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, USA

    Pablo Gurman

  3. Oral Pathology Department, School of Dentistry, University of Buenos Aires, Argentina

    Maria B. Guglielmotti

  4. Oral Pathology Department, School of Dentistry, University of Buenos Aires, Argentina

    Daniel G. Olmedo

  5. University of Buenos Aires, Argentina

    Alejandro Berra

  6. Department of Ophthalmology, Hospital Universitario Austral, Argentina

    Mario J. Saravia

Authors
  1. Orlando Auciello
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  2. Pablo Gurman
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  3. Maria B. Guglielmotti
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  4. Daniel G. Olmedo
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  5. Alejandro Berra
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  6. Mario J. Saravia
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Correspondence to Orlando Auciello.

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Auciello, O., Gurman, P., Guglielmotti, M.B. et al. Biocompatible ultrananocrystalline diamond coatings for implantable medical devices. MRS Bulletin 39, 621–629 (2014). https://doi.org/10.1557/mrs.2014.134

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