Skip to main content
SpringerLink
Log in

Stabilising lamellar stacks of lipid bilayers with soft confinement and steric effects

  • Regular Article
  • Published:
The European Physical Journal E Aims and scope Submit manuscript

Abstract

Structure and interactions stabilising the lamellar stack of mixed lipid bilayers in their fluid state are investigated by means of small-angle X-ray scattering. The (electrically neutral) bilayers are composed of a mixtures of lecithin, a zwitterionic phospholipid, and Simulsol, a non-ionic cosurfactant with an ethoxylated polar head. The soft confinement of the bilayer hydrophilic components is varied by changing hydration and bilayer composition, as well as the length of the cosurfactant polar head. Structural transitions are observed at low hydration, in the stacking order for the longer cosurfactant, and in the mixed bilayers for the shorter one. At higher hydration, the swelling of the lamellar stacks occurs with a significant, but continuous evolution in the mixed bilayer structure. The bilayer structural changes are discussed in analogy with the so-called “brush-to-mushroom” transition induced by lateral confinement, relevant for long linear polymers grafted onto rigid surfaces, taking also into account the role of vertical confinement.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. R. Jelinek, S. Kolusheva, Biotechnol. Adv. 19, 109 (2001).

    Article  Google Scholar 

  2. E. Sackmann, Science 271, 43 (1996).

    Article  ADS  Google Scholar 

  3. G. Scolan, PhD in pharmacy: Applications nanobiotechnologie et thérapeutiques des membranes en bicouches lipidiques (Grenoble, 2012).

  4. D.P. Nikolelis, T. Hianik, U.J. Krull, Electroanalysis 11, 7 (1999).

    Article  Google Scholar 

  5. M. Mezei, V. Gulasekharam, Life Sci. 26, 1473 (1980).

    Article  Google Scholar 

  6. S. Akhtar, R.L. Juliano, J. Controll. Release 22, 47 (1992).

    Article  Google Scholar 

  7. W. Helfrich, Z. Naturforsch 33a, 305 (1978).

    ADS  Google Scholar 

  8. C.R. Safinya, D. Roux, G.S. Smith, S.K. Sinha, P. Dimon, N.A. Clark, A.-M. Bellocq, Phys. Rev. Lett. 57, 2718 (1986).

    Article  ADS  Google Scholar 

  9. D. Roux, C.R. Safinya, J. Phys. (Paris) 49, 307 (1988).

    Article  Google Scholar 

  10. I. Szleifer, D. Kramer, A. Ben-Shaul, D. Roux, W.M. Gelbart, Phys. Rev. Lett. 60, 1966 (1988).

    Article  ADS  Google Scholar 

  11. M.B. Schneider, J.T. Jenkins, W.W. Webb, J. Phys. (Paris) 45, 1457 (1984).

    Article  Google Scholar 

  12. C.R. Safinya, E.B. Sirota, D. Roux, G.S. Smith, Phys. Rev. Lett. 62, 1134 (1989).

    Article  ADS  Google Scholar 

  13. M. Winterhalter, W. Helfrich, J. Phys. Chem. 92, 6865 (1988).

    Article  Google Scholar 

  14. J.L. Harden, C. Marques, J.-F. Joanny, Langmuir 8, 1170 (1992).

    Article  Google Scholar 

  15. H.N.W. Lekkerkerker, Physica A 140, 319 (1989).

    Article  ADS  Google Scholar 

  16. S.T. Milner, T.A. Witten, J. Phys. (Paris) 49, 1951 (1988).

    Article  Google Scholar 

  17. J.T. Brooks, M.E. Cates, J. Chem. Phys. 99, 5467 (1993).

    Article  ADS  Google Scholar 

  18. F. Clement, J.-F. Joanny, J. Phys. II 7, 973 (1997).

    Google Scholar 

  19. P. Kekicheff, B. Cabane, M. Rawiso, J. Colloid Interface Sci. 102, 51 (1984).

    Article  Google Scholar 

  20. E.Z. Radlinska, T. Gulik-Krzywicki, F. Lafuma, D. Langevin, W. Urbach, C.E. William, R. Ober, Phys. Rev. Lett. 74, 4237 (1995).

    Article  ADS  Google Scholar 

  21. M.-F. Ficheux, A.-M. Bellocq, F. Nallet, J. Phys. II 5, 823 (1995).

    Google Scholar 

  22. C. Ligoure, G. Bouglet, G. Porte, O. Diat, J. Phys. II 7, 473 (1997).

    Google Scholar 

  23. T. Pott, A. Colin, L. Navailles, D. Roux, Interface Sci. 11, 249 (2003).

    Article  Google Scholar 

  24. E. Andreoli de Oliveira, E.R. Teixeira da Silva, A. Février, E. Grelet, F. Nallet, L. Navailles, EPL 91, 28001 (2010).

    Article  ADS  Google Scholar 

  25. E.R. Teixeira da Silva, E. Andreoli de Oliveira, A. Février, F. Nallet, L. Navailles, Eur. Phys. J. E 34, 83 (2011).

    Article  Google Scholar 

  26. B.B. Gerbelli, R.L. Rubim, E.R. Silva, F. Nallet, L. Navailles, C.L.P. Oliveira, E.A. de Oliveira, Langmuir 29, 13717 (2013).

    Article  Google Scholar 

  27. F. Nallet, R. Laversanne, D. Roux, J. Phys. II 3, 487 (1993).

    Google Scholar 

  28. C.L.P. Oliveira, B.B. Gerbelli, E.R.T. Silva, F. Nallet, L. Navailles, E.A. Oliveira, J.-S. Pedersen, J. Appl. Crystallogr. 45, 1278 (2012).

    Article  Google Scholar 

  29. A. Caillé, C. R. Hebdo. Acad. Sci. Paris B 274, 891 (1972).

    Google Scholar 

  30. F. Nallet, D. Roux, J. Prost, J. Phys. (Paris) 50, 3147 (1989).

    Article  Google Scholar 

  31. F. Nallet, D. Roux, C. Quilliet, P. Fabre, S.T. Milner, J. Phys. II 4, 1477 (1994).

    Google Scholar 

  32. C. Ligoure, J. Phys.: Condens. Matter 17, S2911 (2005).

    ADS  Google Scholar 

  33. W. Helfrich, R.M. Servuss, Nuovo Cimento 3, 137 (1984).

    Article  Google Scholar 

  34. R. Strey, R. Schomäcker, D. Roux, F. Nallet, U. Olsson, J. Chem. Soc. Faraday Trans. 86, 2253 (1990).

    Article  Google Scholar 

  35. D. Roux, F. Nallet, É. Freyssingeas, G. Porte, P. Bassereau, M. Skouri, J. Marignan, Europhys. Lett. 17, 575 (1992).

    Article  ADS  Google Scholar 

  36. É. Freyssingeas, D. Roux, F. Nallet, J. Phys.: Condens. Matter 8, 2801 (1996).

    ADS  Google Scholar 

  37. V. Luzzati, H. Mustacchi, A. Skoulios, F. Husson, Acta Cryst. 13, 660 (1960).

    Article  Google Scholar 

  38. V. Luzzati, F. Husson, J. Cell Biol. 19, 207 (1962).

    Article  Google Scholar 

  39. R. Lipowsky, S. Leibler, Phys. Rev. Lett. 56, 2541 (1986).

    Article  ADS  Google Scholar 

  40. R. Podgornik, V.A. Parsegian, Langmuir 8, 557 (1992).

    Article  Google Scholar 

  41. S.T. Milner, D. Roux, J. Phys. I 2, 1741 (1992).

    Google Scholar 

  42. V.A. Parsegian, N. Fuller, R.P. Rand, Proc. Natl. Acad. Sci. U.S.A. 76, 2750 (1979).

    Article  ADS  Google Scholar 

  43. T. Gulik-Krzywicki, E. Rivas, V. Luzzati, J. Mol. Biol. 27, 303 (1967).

    Article  Google Scholar 

  44. S.T. Milner, T.A. Witten, M.E. Cates, Macromolecules 21, 2610 (1988).

    Article  ADS  Google Scholar 

  45. B.F.B. Silva, E.F. Marques, U. Olsson, J. Phys. Chem. B 111, 13520 (2007).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre de recherche Paul-Pascal-CNRS, Université de Bordeaux, 115 avenue du Docteur-Schweitzer, F-33600, Pessac, France

    K. Bougis, N. Ziane, J. Peyencet, A. Bentaleb, A. Février, L. Navailles & F. Nallet

  2. Instituto de Física-GFCx, Universidade de São Paulo, P.O.B. 66318, 05314-970, São Paulo, SP, Brazil

    R. Leite Rubim, C. L. P. Oliveira & E. Andreoli de Oliveira

Authors
  1. K. Bougis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Leite Rubim
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. N. Ziane
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. Peyencet
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. Bentaleb
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. Février
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. C. L. P. Oliveira
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. E. Andreoli de Oliveira
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. L. Navailles
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. F. Nallet
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to F. Nallet.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bougis, K., Leite Rubim, R., Ziane, N. et al. Stabilising lamellar stacks of lipid bilayers with soft confinement and steric effects. Eur. Phys. J. E 38, 78 (2015). https://doi.org/10.1140/epje/i2015-15078-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1140/epje/i2015-15078-3

Keywords

Search

Navigation