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Synthesis and Structure of 5-Aryl-4-[hydroxy(phenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones

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Abstract

The reactions of tryptamine with aromatic aldehyde and methyl benzoylpyruvate at room temperature leads to the formation of 5-aryl-4-[hydroxy(phenyl)Methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones.

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Acknowledgments

The studies were performed using the equipment of the resource centers of the Science Park of St. Petersburg State University “Magnetic Resonance Research Methods,” “Methods of Analysis of the Composition of the Substance,” and the Resource Educational Center “Chemistry.”

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, Perm, 614990, Russia

    V. L. Gein & L. I. Varkentin

  2. E.A. Vagner Perm State Medical University, Perm, 614990, Russia

    M. I. Kazantseva

  3. Perm State National Research University, Perm, 614990, Russia

    M. V. Dmitriev

  4. St. Petersburg State University, St. Petersburg, 199034, Russia

    A. N. Yankin

Authors
  1. V. L. Gein
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  2. L. I. Varkentin
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  3. M. I. Kazantseva
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  4. M. V. Dmitriev
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  5. A. N. Yankin
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Corresponding author

Correspondence to V. L. Gein.

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Conflict of Interest

No conflict of interest was declared by the authors.

Russian Text © The Author(s), 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 11, pp. 1673–1678.

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Gein, V.L., Varkentin, L.I., Kazantseva, M.I. et al. Synthesis and Structure of 5-Aryl-4-[hydroxy(phenyl)methylene]-1-[2-(1H-indol-3-yl)ethyl]pyrrolidine-2,3-diones. Russ J Gen Chem 89, 2196–2200 (2019). https://doi.org/10.1134/S1070363219110057

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  • DOI: https://doi.org/10.1134/S1070363219110057

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