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Determination of benzimidazoles in fruits by open-tubular capillary electrochromatography based on ionic liquids grafted covalent organic frameworks

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Abstract

A novel capillary electrochromatography method has been developed for the simultaneous quantification of ten benzimidazole fungicides in fruits. Herein, covalent organic frameworks (COFs) and ionic liquids (ILs) were successfully introduced to prepare open-tubular capillary column to improve the loading capacity and separation performance. The parameters effecting the analytical performance including pH and concentration of running buffer, separation voltage and the addition of organic solvent were investigated systematically. Under the optimized conditions, the method allowed the baseline separation of ten benzimidazole fungicides, and showed a good linearity in the range of 3.5–200 μg kg−1 with the detection limits between 1.0 and 2.8 μg kg−1. The intraday and interday precisions for recoveries were lower than 7.9% and 12.2%, respectively. Intraday and interday precisions for their retention times were lower than 3.2% and 6.6%, respectively. Satisfactory recoveries for grape, pear and orange samples at two concentrations were obtained ranging from 85.0 to 95.9% with RSDs lower than 7.8%, demonstrating the potential applications of the open-tubular capillary electrochromatography method for trace benzimidazole fungicides analysis in fruits.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

This work was supported by the Scientific Research and Development Foundation of Tianjin Education Commission Scientific Research Plan Project (No.2018KJ186).

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Authors and Affiliations

  1. Department of Food Science and Biology Engineering, Tianjin Agricultural University, Tianjin, 300384, China

    Cuicui Liu, Buyi Zhao, Xiaobing Liu & Ailin Zhang

Authors
  1. Cuicui Liu
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  2. Buyi Zhao
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  3. Xiaobing Liu
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  4. Ailin Zhang
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Contributions

CL: conceptualization and writing original draft. BZ: optimization of chromatographic separation, method characterization, and writing original draft. XL: preparation of ILs@COFs coated capillary column, optimization of chromatographic conditions, and writing original draft. AZ: preparation of standards and samples, and writing original draft.

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Correspondence to Cuicui Liu.

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Liu, C., Zhao, B., Liu, X. et al. Determination of benzimidazoles in fruits by open-tubular capillary electrochromatography based on ionic liquids grafted covalent organic frameworks. ANAL. SCI. 38, 1277–1287 (2022). https://doi.org/10.1007/s44211-022-00157-9

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  • DOI: https://doi.org/10.1007/s44211-022-00157-9

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