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Synergistic Antibacterial Action of Iron, Silver, and Vanadium Ternary Oxide Nanoparticles: Green Mediated Synthesis Using Tailored Plant Extract Blends

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Abstract

This study explores a green approach in nanotechnology, synthesizing PVP-capped Gum Arabic emulsified ternary oxides of Fe–Ag–V nanoparticles using a blend of mushroom, guava, and plantain peel extracts. The nanoparticles acquired displayed irregular shapes and distinctive clustered patterns, as observed via scanning electron microscopy. An analysis using dynamic light scattering revealed a narrow size distribution, showcasing an average diameter of 291.6 nm and a polydispersity index of 0.137. The nanoparticles displayed exceptional inhibitory effects against Staphylococcus aureus, demonstrating a Minimum Inhibitory Concentration (MIC) of 0.3125 mg/ml and a Minimum Bactericidal Concentration (MBC) of 1.25 mg/ml. While the MIC and MBC values for other bacterial strains were slightly higher, the nanoparticles exhibited significant inhibitory actions, showcasing their potential in managing a spectrum of bacterial infections. These findings highlight their substantial potential at low concentrations, suggesting promising applications in diverse fields. This study represents a significant advancement in nanoparticle technology, offering a sustainable approach and valuable insights into their versatile applications. The nanoparticles’ multifaceted nature and strong antimicrobial capabilities position them as transformative tools in biomedicine, catalysis, and beyond, ushering in a new era of innovative solutions for real-world challenges.

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The data and materials used in this study are available upon request.

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Acknowledgements

The authors express heartfelt gratitude to TETFUND for their generous research funding, which played a pivotal role in the successful completion of their study. This support enabled crucial experiments, access to essential resources, and the presentation of findings at conferences, elevating the overall quality and impact of the research. TETFUND’s commitment to fostering research excellence and their significant contribution to the academic community is deeply appreciated. Their support not only advanced the authors’ careers but also contributed to the progress of knowledge in Nanotechnology. The authors extend their wholehearted thanks to TETFUND for their unwavering support and acknowledge the valuable opportunity provided by their research funding.

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This work was funded by TETFUND.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Physical Sciences, University of Benin, P.M.B.1154, Benin City, Nigeria

    Esther U. Ikhuoria, Ita E. Uwidia & Ikechukwu D. Chikaodili

  2. Department of Microbiology, Faculty of Life Sciences, University of Benin, P.M.B. 1154, Benin City, Nigeria

    Rachel O. Okojie

  3. Department of Research Outreach, Rubber Research Institute of Nigeria, Iyanomo, P.M.B, 1049, Benin City, Nigeria

    Ikhazuagbe H. Ifijen

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  1. Esther U. Ikhuoria
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  4. Ikhazuagbe H. Ifijen
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  5. Ikechukwu D. Chikaodili
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Correspondence to Esther U. Ikhuoria or Ikhazuagbe H. Ifijen.

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Ikhuoria, E.U., Uwidia, I.E., Okojie, R.O. et al. Synergistic Antibacterial Action of Iron, Silver, and Vanadium Ternary Oxide Nanoparticles: Green Mediated Synthesis Using Tailored Plant Extract Blends. Biomedical Materials & Devices (2024). https://doi.org/10.1007/s44174-024-00162-8

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