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Electrospun Nanofibrous Materials for Wound Healing

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Abstract

Wound dressing materials which are capable of meeting the demands of accelerating wound closure and promoting wound healing process have being highly desired. Electrospun nanofibrous materials show great application potentials for wound healing owing to relatively large surface area, better mimicry of native extracellular matrix, adjustable waterproofness and breathability, and programmable drug delivery process. In this review article, we begin with a discussion of wound healing process and current commercial wound dressing materials. Then, we emphasize on electrospun nanofibrous materials for wound dressing, covering the efforts for controlling fiber alignment and morphology, constructing 3D scaffolds, developing waterproof-breathable membrane, governing drug delivery performance, and regulating stem cell behavior. Finally, we finish with challenges and future prospects of electrospun nanofibrous materials for wound dressings.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (81771338), Natural Science Foundation of Shanghai (19ZR1470500), the Science and Technology Commission of Shanghai Municipality (18511109500), and the Fundamental Research Funds for the Central Universities (223201900081).

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  1. Yuping Dong and Yuqi Zheng contributed equally to the work.

Authors and Affiliations

  1. State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Textiles, Donghua University, Shanghai, 201620, China

    Yuping Dong, Keyan Zhang, Yueming Yao, Lihuan Wang & Bin Ding

  2. College of Materials Science and Engineering, Donghua University, Shanghai, 201620, China

    Yuqi Zheng

  3. Innovation Center for Textile Science and Technology, Donghua University, Shanghai, 200051, China

    Xiaoran Li, Jianyong Yu & Bin Ding

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  1. Yuping Dong
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Correspondence to Xiaoran Li or Bin Ding.

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Dong, Y., Zheng, Y., Zhang, K. et al. Electrospun Nanofibrous Materials for Wound Healing. Adv. Fiber Mater. 2, 212–227 (2020). https://doi.org/10.1007/s42765-020-00034-y

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