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Use available data to optimise antibiotic use in critically ill children

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Abstract

Optimising antibiotic use has become increasingly important due to the rise of bacterial resistance in pathogens detected in critically ill children. Additionally, many critically ill children are receiving subtherapeutic antibiotic dosages. Determining the best antibiotic, dosage, duration and route of administration in these children relies largely on clinicians’ expertise, as limited guidance is available. Using pharmacokinetic data and implementing antibiotic stewardship programmes to collect, analyse and share information are options for improving antibiotic optimisation in critically ill children.

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Correspondence to Arnold Lee.

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The preparation of this review was not supported by any external funding.

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C. Fenton, a contracted employee of Adis International Ltd/Springer Nature, and A. Lee, a salaried employee of Adis International Ltd/Springer Nature, declare no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content.

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Fenton, C., Lee, A. Use available data to optimise antibiotic use in critically ill children. Drugs Ther Perspect 38, 322–328 (2022). https://doi.org/10.1007/s40267-022-00924-8

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  • DOI: https://doi.org/10.1007/s40267-022-00924-8

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