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Eczematous drug eruptions mostly manageable with emollients and corticosteroids

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Abstract

Eczematous drug eruptions (EDEs) constitute up to 10% of cutaneous drug reactions, with biologics and some newer cancer treatments and antivirals regularly implicated. EDEs are generally mild, although bacterial superinfection is a risk. Drug withdrawal and rechallenge, where practical, is the gold standard diagnostic test. Dry skin, cutaneous immunomodulation and sometimes type IV hypersensitivity reactions underlie EDEs and treatments reflect this, with most patients responding to emollients and corticosteroids.

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Correspondence to Connie Kang.

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The preparation of this review was not supported by any external funding.

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C. Fenton, a contracted employee of Adis International Ltd/Springer Nature, and C. Kang, a salaried employee of Adis International Ltd/Springer Nature, declare no relevant conflicts of interest. All authors contributed to the review and are responsible for the article content.

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Fenton, C., Kang, C. Eczematous drug eruptions mostly manageable with emollients and corticosteroids. Drugs Ther Perspect 38, 13–18 (2022). https://doi.org/10.1007/s40267-021-00881-8

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  • DOI: https://doi.org/10.1007/s40267-021-00881-8

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