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Diclofenac Transdermal Patch: A Potential Ingress to Maxillofacial Surgery

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Abstract

Purpose

To evaluate the analgesic efficacy of a diclofenac transdermal patch with diclofenac intra muscular injection in the immediate postoperative period in patients undergoing major oral surgical procedures.

Materials and Methods

Subjects who underwent bijaw surgeries for surgical correction of various dentofacial deformities were included. Sixty such patients who belonged to the above entity were randomly categorized into two groups from Jan 2012–Aug 2015. Group A (study group) received a single dose of 100 mg transdermal diclofenac patch, Group B (control group) received 75 mg intramuscular diclofenac and tramadol HCl 2 mg/kg body wt was used as rescue analgesic in the immediate post operative phase. The analgesic efficacy of the drugs are evaluated on periodic patient’s perception of pain in the immediate postoperative phase of 2nd, 6th, 12th, 24th and 48 hours.

Results

The mean VAS score in Group A was 2, mean duration of analgesia was 16 h 9 min, and in Group B the mean VAS score was 4, duration of analgesia was 8 h and 4 min. Tramadol HCl was given as rescue analgesia in 22 % (6) of patients belonging to Group A. None of the patients from both the groups reported local complications.

Conclusion

A noninvasive application of a single dose of 100 mg transdermal diclofenac patch is more effective than intramuscular diclofenac (75 mg) in the immediate post operative phase, without any significant side-effects is a novel ingress into the field of oral and maxillofacial surgery for post operative pain management.

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Acknowledgments

The authors would like to thank Dr. Pranavi and Dr. Sasank for their general support and assistance.

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Authors and Affiliations

  1. Sri Sai College of Dental Surgery, Vikarabad, India

    Anisha Perepa

  2. Department of Oral and Maxillofacial Surgery, Sri Sai College of Dental Surgery, Vikarabad, India

    Brig Ramen Sinha, Uday Kiran Uppada & AVSS Subramanya Kumar

  3. Department of Anesthesiology, Sri Sai College of Dental Surgery, Vikarabad, India

    AVSS Subramanya Kumar

Authors
  1. Anisha Perepa
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  2. Brig Ramen Sinha
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  3. Uday Kiran Uppada
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  4. AVSS Subramanya Kumar
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Correspondence to Anisha Perepa.

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Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Perepa, A., Sinha, B.R., Uppada, U.K. et al. Diclofenac Transdermal Patch: A Potential Ingress to Maxillofacial Surgery. J. Maxillofac. Oral Surg. 16, 170–174 (2017). https://doi.org/10.1007/s12663-016-0941-3

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  • DOI: https://doi.org/10.1007/s12663-016-0941-3

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