Abstract
Vitamin D is not only essential in bone metabolism and calcium homeostasis but also has anticarcinogenic properties in multiple malignancies, including breast cancer. Vitamin D deficiency is a potentially modifiable risk factor that may be easily targeted for breast cancer risk reduction through supplementation. Several epidemiological studies have demonstrated an inverse relationship between dietary intake and blood levels of vitamin D and breast cancer risk; however, the results have been inconsistent. Despite some promising findings, further randomized controlled trials of vitamin D supplements are needed to determine the role of vitamin D in breast cancer prevention.
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Jennifer K. Lue and Katherine D. Crew declare that they have no conflicts of interest.
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Lue, J.K., Crew, K.D. Vitamin D and Reduction of Breast Cancer Risk. Curr Breast Cancer Rep 7, 90–97 (2015). https://doi.org/10.1007/s12609-015-0180-5
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DOI: https://doi.org/10.1007/s12609-015-0180-5