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The Enigma of New Daily Persistent Headache: What Solutions for Pediatric Age?

  • Childhood and Adolescent Headache (SE Evers, Section Editor)
  • Published:
Current Pain and Headache Reports Aims and scope Submit manuscript

Abstract

Purpose of review

To analyze systematically the evidence currently available from the literature regarding the diagnosis, clinical characteristics, treatment and outcome of new daily persistent headache (NDPH).

Recent findings

NDPH is a primary headache characterized by an abrupt onset with continuous daily pain that can persist for many months. Although self-limiting forms have been described, NDPH is frequently associated with high disability even in children and adolescents. For this reason, it is very important to recognize it from a diagnostic point of view and to treat it.

Summary

We found little specific data on NDPH in developmental age. Most of the therapy studies have been conducted on adults with conflicting data. Currently, pediatric NDPH therapy is based on experiences in adult patients and in individuals with other forms of primary chronic headache, hence the need for more pediatric studies to fill this information gap.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Author information

Authors and Affiliations

  1. Pediatric Headache Center, Neuroscience Department, Bambino Gesù Children Hospital, IRCCS, Rome, Italy

    Laura Papetti, Giorgia Sforza, Samuela Tarantino, Fabiana Ursitti, Michela Ada Noris Ferilli & Massimiliano Valeriani

  2. Child Neurology and Psychiatry Unit, Tor Vergata University of Rome, Rome, Italy

    Ilaria Frattale

  3. Neuroscience Department, Neurology Unit, Bambino Gesù Children Hospital, IRCCS, Rome, Italy

    Federico Vigevano

  4. Center for Sensory-Motor Interaction, Aalborg University, Denmark Neurology Unit, Aalborg, Denmark

    Massimiliano Valeriani

Authors
  1. Laura Papetti
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  2. Giorgia Sforza
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  3. Ilaria Frattale
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  4. Samuela Tarantino
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  5. Fabiana Ursitti
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  6. Michela Ada Noris Ferilli
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  7. Federico Vigevano
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  8. Massimiliano Valeriani
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Correspondence to Massimiliano Valeriani.

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This article is part of the Topical Collection on Childhood and Adolescent Headache

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Papetti, L., Sforza, G., Frattale, I. et al. The Enigma of New Daily Persistent Headache: What Solutions for Pediatric Age?. Curr Pain Headache Rep 26, 165–172 (2022). https://doi.org/10.1007/s11916-022-01011-3

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