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New Daily Persistent Headache in Children and Adolescents

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Abstract

New daily persistent headache (NDPH) is a form of chronic daily headache (CDH) that may have features of both migraine and tension-type headache. In contrast with other types of CDH, NDPH is characterized by patients recalling the specific date their unremitting daily headache began. In comparison, chronic tension-type headache and chronic migraine are preceded by a gradually increasing frequency of headache. After several months, all three of these CDH forms often have a similar phenotype, making early history a key to diagnosing NDPH. Evaluations to exclude secondary causes are necessary but usually negative. NDPH is difficult to treat and requires a multimodal approach. Questions regarding NDPH remain unanswered. Additional prospective studies are necessary to further understand, characterize, diagnose, and treat NDPH.

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Disclosure

Dr. Rothner received a grant from GlaxoSmithKline for research on Treximet in adolescents. No other potential conflicts of interest relevant to this article were reported.

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Authors and Affiliations

  1. Department of Neurology, Center for Headache and Pain/T33, Cleveland Clinic Neurological Institute, 9500 Euclid Avenue, Cleveland, OH, 44195, USA

    Eric P. Baron

  2. Center for Pediatric Neurology/S60, Cleveland Clinic Neurological Institute, 9500 Euclid Avenue, Cleveland, OH, 44195, USA

    A. David Rothner

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  1. Eric P. Baron
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  2. A. David Rothner
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Correspondence to Eric P. Baron.

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Baron, E.P., Rothner, A.D. New Daily Persistent Headache in Children and Adolescents. Curr Neurol Neurosci Rep 10, 127–132 (2010). https://doi.org/10.1007/s11910-010-0097-3

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