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Interstitial Cystitis/Bladder Pain Syndrome: a Review and an Update

  • Post-Prostatectomy and Acquired Voiding Dysfunction (V Tse, Section Editor)
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Abstract

Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by pelvic pain and lower urinary tract symptoms. The evolution of nomenclature of IC/BPS has experienced a long history. The disease etiology is not yet fully understood; potential pathophysiologic causes proposed include defect of layer of glycosaminoglycan (GAG) on the apical surface of bladder floor; autoimmune, inflammatory, and neurogenic mechanisms; infection; and so on. There are a lot of strategies to cure IC/BPS, mainly including behavioral therapy, oral medicines, intravesical treatments, and intradetrusor botulinum toxin A (BTXA) injection. But none of them is curative. Most treatments are aimed at controlling symptom and improving the quality of life of patients. In this article, we will talk about the new progress of definition, etiology, and treatment on IC/BPS.

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  1. Department of Urology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of China

    Zhiwei Fang & Kexin Xu

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  1. Zhiwei Fang
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Fang, Z., Xu, K. Interstitial Cystitis/Bladder Pain Syndrome: a Review and an Update. Curr Bladder Dysfunct Rep 11, 391–398 (2016). https://doi.org/10.1007/s11884-016-0387-y

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