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A systematic review and meta-analysis comparing robotic single-site versus multi-port myomectomy

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Abstract

The objective of this study was to compare the surgical outcomes of robotic multi-site myomectomy (RMSM) with those of robotic single-site myomectomy (RSSM). We conducted a systematic search of the PubMed, CINAHL, Scopus, and Google Scholar databases for articles comparing RMSM and RSSM until March 2023. Data analysis was performed using Review Manager V5.3 (Cochrane), and the main outcomes examined were perioperative outcomes and complications. A total of five studies, covering 823 patients, were included in the analysis. The statistical analysis revealed no significant differences between RMSM and RSSM with regard to docking time (p = 0.9), console time (p = 0.37), estimated blood loss (p = 0.38), postoperative hemoglobin (Hb) loss (p = 0.61), transfusion rate (p = 0.25), length of stay (p = 0.08), conversion (p = 0.36), postoperative fever (p = 0.46), intraoperative complication (p = 0.23), or postoperative complication (p = 0.12). However, compared to RMSM, RSSM was found to have a shorter morcellation time (weighted mean difference [WMD] − 4.52 min; 95% confidence interval [CI] − 6.89 to 2.15; p = 0.0002), less total operative time (WMD − 9.83 min; 95% CI − 18.27 to − 1.38; p = 0.02), lower Hb change (WMD − 0.28 g/dL; 95% CI − 0.49 to − 0.07; p = 0.008), and fewer overall complications (odds ratio [OR] 0.55; 95% CI 0.32–0.92; p = 0.02). Our findings suggest that RSSM is a safe and effective alternative to RMSM for the most studied outcomes. Further randomized studies are necessary to validate these results.

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References

  1. Okolo S (2008) Incidence, aetiology and epidemiology of uterine fibroids. Best Pract Res Clin Obstet Gynaecol 22(4):571–588

    Article  PubMed  Google Scholar 

  2. Falcone T, Parker WH (2013) Surgical management of leiomyomas for fertility or uterine preservation. Obstet Gynecol 121(4):856–868

    Article  PubMed  Google Scholar 

  3. Lee JH, Choi JS, Jeon SW, Son CE, Lee SJ, Lee YS (2010) Single-port laparoscopic myomectomy using transumbilical GelPort access. Eur J Obstet Gynecol Reprod Biol 153(1):81–84

    Article  PubMed  Google Scholar 

  4. Lee D, Lee JR, Suh CS, Kim SH (2019) A systematic review and meta-analysis comparing single port laparoscopic myomectomy with conventional laparoscopic myomectomy. Eur J Obstet Gynecol Reprod Biol 239:52–59

    Article  PubMed  Google Scholar 

  5. Bhave Chittawar P, Franik S, Pouwer AW, Farquhar C (2014) Minimally invasive surgical techniques versus open myomectomy for uterine fibroids. Cochrane Database of Syst Rev. https://doi.org/10.1002/14651858.CD004638.pub3

    Article  Google Scholar 

  6. Iavazzo C, Mamais I, Gkegkes ID (2016) Robotic assisted vs laparoscopic and/or open myomectomy: systematic review and meta-analysis of the clinical evidence. Arch Gynecol Obstet 294(1):5–17

    Article  PubMed  Google Scholar 

  7. Giovannopoulou E, Prodromidou A, Blontzos N, Iavazzo C (2021) The emerging role of robotic single-site approach for myomectomy: a systematic review of the literature. Surg Innov 28(3):352–359

    Article  PubMed  Google Scholar 

  8. Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ (Clin Res Ed) 355:i4919

    Google Scholar 

  9. Wells GA, Shea B, O’Connell D, Peterson J, Welch V, Losos M, Tugwell P (2000) The Newcastle–Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Oxford

  10. Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (2019) Cochrane handbook for systematic reviews of interventions. Wiley, Amsterdam

    Book  Google Scholar 

  11. Hozo SP, Djulbegovic B, Hozo I (2005) Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5:13

    Article  PubMed  PubMed Central  Google Scholar 

  12. Sterne JA, Gavaghan D, Egger M (2000) Publication and related bias in meta-analysis: power of statistical tests and prevalence in the literature. J Clin Epidemiol 53(11):1119–1129

    Article  CAS  PubMed  Google Scholar 

  13. Lau J, Ioannidis JP, Terrin N, Schmid CH, Olkin I (2006) The case of the misleading funnel plot. BMJ (Clin Res Ed) 333(7568):597–600

    Article  Google Scholar 

  14. Ahn SH, Park JH, Kim HR, Cho S, Lee M, Seo SK, Choi YS, Lee BS (2021) Robotic single-site versus multi-port myomectomy: a case-control study. BMC Surg 21(1):264

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Choi SH, Hong S, Kim M, Bae HS, Kim MK, Kim ML, Jung YW, Yun BS, Seong SJ (2019) Robotic-assisted laparoscopic myomectomy: the feasibility in single-site system. Obstet Gynecol Sci 62(1):56–64

    Article  PubMed  Google Scholar 

  16. Kim JM, Lee YH, Chong GO, Lee SR, Hong DG (2022) Comparison of multi- and single-site robotic myomectomy using the Da Vinci(®) SP surgical system: a propensity score matching analysis. J Clin Med 11(23):6905

    Article  PubMed  PubMed Central  Google Scholar 

  17. Lee SR, Kim JH, Lee YJ, Lee SW, Park JY, Suh DS, Kim DY, Kim SH, Kim YM, Kim YT (2021) Single-incision versus multiport robotic myomectomy: a propensity score matched analysis of surgical outcomes and surgical tips. J Clin Med 10(17):3957

    Article  PubMed  PubMed Central  Google Scholar 

  18. Moawad GN, Tyan P, Paek J, Tappy EE, Park D, Choussein S, Srouji SS, Gargiulo A (2019) Comparison between single-site and multiport robot-assisted myomectomy. J Robot Surg 13(6):757–764

    Article  PubMed  Google Scholar 

  19. Shin HJ, Yoo HK, Lee JH, Lee SR, Jeong K, Moon HS (2020) Robotic single-port surgery using the da Vinci SP® surgical system for benign gynecologic disease: a preliminary report. Taiwan J Obstet Gynecol 59(2):243–247

    Article  PubMed  Google Scholar 

  20. Choi EJ, Rho AM, Lee SR, Jeong K, Moon HS (2017) Robotic single-site myomectomy: clinical analysis of 61 consecutive cases. J Minim Invasive Gynecol 24(4):632–639

    Article  PubMed  Google Scholar 

  21. Gargiulo AR, Choussein S, Srouji SS, Cedo LE, Escobar PF (2017) Coaxial robot-assisted laparoendoscopic single-site myomectomy. J Robot Surg 11(1):27–35

    Article  PubMed  Google Scholar 

  22. Chang HK, Hur SY, Park JS, Lee KH (2015) Hybrid surgical technique: single-site laparoscopic myomectomy using robotic-assisted laparoscopic suture. J Minim Invasive Gynecol 22(6s):S211

    Article  CAS  PubMed  Google Scholar 

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WL: protocol development, methodology. KP and JY: data collection and management. WL: writing original draft, and visualization. PY: study supervision.

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Correspondence to Ping-yu Zhu.

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Wang, L., Deng, Jy., Li, Kp. et al. A systematic review and meta-analysis comparing robotic single-site versus multi-port myomectomy. J Robotic Surg 17, 1319–1328 (2023). https://doi.org/10.1007/s11701-023-01597-9

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