Abstract
The evaluation of engineering controls for the production or use of carbon nanotubes (CNTs) was investigated at two facilities. These control assessments are necessary to evaluate the current status of control performance and to develop proper control strategies for these workplaces. The control systems evaluated in these studies included ventilated enclosures, exterior hoods, and exhaust filtration systems. Activity-based monitoring with direct-reading instruments and filter sampling for microscopy analysis were used to evaluate the effectiveness of control measures at study sites. Our study results showed that weighing CNTs inside the biological safety cabinet can have a 37 % reduction on the particle concentration in the worker’s breathing zone, and produce a 42 % lower area concentration outside the enclosure. The ventilated enclosures used to reduce fugitive emissions from the production furnaces exhibited good containment characteristics when closed, but they failed to contain emissions effectively when opened during product removal/harvesting. The exhaust filtration systems employed for exhausting these ventilated enclosures did not provide promised collection efficiencies for removing engineered nanomaterials from furnace exhaust. The exterior hoods were found to be a challenge for controlling emissions from machining nanocomposites: the downdraft hood effectively contained and removed particles released from the manual cutting process, but using the canopy hood for powered cutting of nanocomposites created 15–20 % higher ultrafine (<500 nm) particle concentrations at the source and at the worker’s breathing zone. The microscopy analysis showed that CNTs can only be found at production sources but not at the worker breathing zones during the tasks monitored.
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References
ACGIH (2013) Industrial ventilation: a manual of recommended practice for design. In: American conference of governmental industrial hygienists, Cincinnati, Ohio
ANSI, ASHRAE (1995) Standard Method 110: method of testing performance of laboratory fume hoods. American Society of Heating Refrigerating and Air-Conditioning Engineers, Inc., Atlanta
Bekker C, Kuijpers E, Brouwer DH, Vermeulen R, Fransman W (2015) Occupational exposure to nano-objects and their agglomerates and aggregates across various life cycle stages; a broad-scale exposure study. Ann Occup Hyg 59(6):681–704
Bello D, Wardle BL, Yamamoto M, Guzman de Villoria R, Garcia EJ, Hart AJ, Ahn K, Ellenbecker MJ, Hallock M (2009) Exposure to nanoscale particles and fibers during machining of hybrid advanced composites containing carbon nanotubes. J Nanopart Res 11(1):231–249
Brouwer D (2010) Exposure to manufactured nanoparticles in different workplaces. Toxicology 269(2):120–127
Brouwer DK, Gijsbers JHJ, Lurvink MWM (2004) Personal exposure to ultrafine particles in the workplace: exploring sampling techniques and strategies. Ann Occup Hyg 48(5):439–453
Burgess WA, Ellenbecker MJ, Treitman RD (2004) Ventilation for control of the work environment. Wiley-Interscience, Hoboken
Cena LG, Peters TM (2011) Characterization and control of airborne particles emitted during production of epoxy/carbon nanotube nanocomposites. J Occup Environ Hyg 8(2):86–92
Dahm MM, Yencken MS, Schubauer-Berigan MK (2011) Exposure control strategies in the carbonaceous nanomaterial industry. J Occup Environ Med 53(6 Suppl):S68–S73
Dahm MM, Evans DE, Schubauer-Berigan MK, Birch ME, Fernback JE (2012) Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers. Ann Occup Hyg 56(5):542–556
Demou E, Peter P, Hellweg S (2008) Exposure to manufactured nanostructured particles in an industrial pilot plant. Ann Occup Hyg 52(8):695–706
Ferin J, Oberdorster G, Penny DP, Soderholm SC, Gelein R, Piper HC (1990) Increased pulmonary toxicity of ultrafine particles? I. Particle clearance, translocation, morphology. J Aerosol Sci 21:381–384
Ferin J, Oberdörster G, Soderholm S, Gelein R (1991) Pulmonary tissue access of ultrafine particles. J Aerosol Med 4:57–68
Givehchi R, Tan Z (2014) An overview of airborne nanoparticle filtration and thermal rebound theory. Aerosol Air Qual Res 14:45–63
Heim M, Mullins BJ, Wild M, Meyer J, Kasper G (2005) Filtration efficiency of aerosol particles below 20 nanometers. Aerosol Sci Technol 39:782–789
Heitbrink WA, Lo LM (2015) Effect of carbon nanotubes upon emissions from cutting and sanding carbon fibereposy composites. J Nanopart Res 17(8):355
Hotze EM, Phenrat T, Lowry GV (2010) Nanoparticle aggregation: challenges to understand transport and reactivity in the environment. J Environ Qual 39:1909–1924
HSE (2011) Controlling airborne contaminants at work: a guide to local exhaust ventilation (LEV). Series code HSG258. Health and Safety Executive
Huang SH, Chen CW, Chang CP, Lai CY, Chen CC (2007) Penetration of 4.5 nm to aerosol particles through fibrous filters. J Aerosol Sci 38(7):719–727
ICON (2006) A survey of current practices in the nanotechnology workplace: condensed report. International Council on Nanotechnology
Kim CS, Bao L, Okuyama K, Shimada M, Niinuma H (2006) Filtration efficiency of a fibrous filter for nanoparticles. J Nanopart Res 8:215–221
Kim SC, Harrington MS, Pui DYH (2007) Experimental study of nanoparticles penetrations through commercial filter media. J Nanopart Res 9:117–125
Kumar V, Kim JH, Pendyala C, Chernomordik B, Sunkara MK (2008) Gas-phase, bulk production of metal oxide nanowires and nanoparticles using a microwave plasma jet reactor. J Phys Chem Lett 112:17750–17754
Maynard AD, Kuempel ED (2005) Airborne nanostructured particles and occupational health. J Nanopart Res 7(6):587–614
Methner M (2008) Engineering case reports: effectiveness of local exhaust ventilation (LEV) in controlling engineered nanomaterial emissions during reactor cleanout operations. J Occup Environ Hyg 5:D63–D69
Methner MM, Birch ME, Evans DE, Ku BK, Crouch K, Hoover MD (2007) Case study: identification and characterization of potential sources of worker exposure to carbon nanofibers during polymer composite laboratory operations. J Occup Environ Hyg 4(12):D125–D130
NIOSH (1994) NIOSH manual of analytical methods (NMAM) method 7402: asbestos by TEM. National Institute for Occupational Safety and Health, Cincinnati
NIOSH (2009) Approach to safe nanotechnology: managing the health and safety concerns associated with engineered nanomaterials. DHHS (NIOSH) publication no. 2009-125. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati
NIOSH (2013) Current strategies for engineering controls in nanomaterial production and downstream handling processes. DHHS (NIOSH) publication no. 2014-102. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Cincinnati, OH
OSHA (2013) OSHA fact sheet: working safely with nanomaterials, DTSEM FS-3634 01/2013. Occupational Safety and Health Administration, Washington, DC
Peters TM, Elzey S, Johnson R, Park H, Grassian VH, Maher T, O’Shaughnessy P (2009) Airborne monitoring to distinguishing engineered nanomaterials from incidental particles for environmental health and safety. J Occup Environ Hyg 6:73–81
Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WA, Seaton A, Stone V, Brown S, MacNee W, Donaldson K (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3(7):423–428. doi:10.1038/nnano.2008.111
Rengasamy S, Eimer BC, Shaffer RE (2009) Comparison of nanoparticle filtration performance of NIOSH-approved and CE-marked particulate filtering facepiece respirators. Ann Occup Hyg 53(2):117–128
Ryman-Rasmussen JP, Cesta MF, Brody AR, Shipley-Phillips JK, Everitt JI, Tewksbury EW, Moss OR, Wong BA, Dodd DE, Andersen ME, Bonner JC (2009) Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat Nanotechnol 4:747–751
Shin WG, Mulholland GW, Kim SC, Pui DYH (2008) Experimental study of filtration efficiency for nanoparticles below 20 nm at elevated temperatures. J Aerosol Sci 39(6):488–499
Sotiriou GA, Diaz E, Long MS, Godleski J, Brain J, Pratsinis SE, Demokritou P (2011) A novel platform for pulmonary and cardiovascular toxicological characterization of inhaled engineered nanomaterials. Nanotoxicology. doi:10.3109/17435390.2011.604439
SWA (2012) Safe handling and use of carbon nanotubes. Safe Work Australia, Canberra
Takagi A, Hirose A, Nishimura T, Fukumori N, Ogata A, Ohashi N, Kitajima S, Kanno J (2008) Induction of mesothelioma in p53+/− mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33(1):105–116
Tsai CS-J (2013) Potential inhalation exposure and containment efficiency when using hoods for handling nanoparticles. J Nanopart Res 15:1880
Tsai S-J, Ashter A, Ada E, Mead J, Barry C, Ellenbecker M (2008) Airborne nanoparticle release associated with the compounding of nanocomposites using nanoalumina as fillers. J Aerosol Air Qual Res 8(2):160–177
Tsai S-J, Ada E, Isaacs JA, Ellenbecker MJ (2009a) Airborne nanoparticle exposures associated with the manual handling of nanoalumina and nanosilver in fume hoods. J Nanopart Res 11:147–161
Tsai S-J, Hofmann M, Kong J, Hallock M, Ada E, Ellenbecker M (2009b) Characterization and evaluation of nanoparticle release during the synthesis of single-walled and multi-walled carbon nanotubes by Chemical Vapor Deposition. Environ Sci Technol 43(15):6017–6023
Tsai SJ, Hoffman M, Hallock MF, Ada E, Kong J, Ellenbecker MJ (2009c) Characterization and evaluation of nanoparticle release during the synthesis of single-walled and multiwalled carbon nanotubes by chemical vapor deposition. Environ Sci Technol 43:6017–6023
Tsai SJ, Huang RF, Ellenbecker MJ (2010) Airborne nanoparticle exposures while using constant-flow, constant-velocity, and air-curtain-isolated fume hoods. Ann Occup Hyg 54(1):78–87
Tsai S-J, Echevarría-Vega M, Sotiriou G, Santeufemio C, Schmidt D, Demokritou P, Ellenbecker M (2012a) Evaluation of environmental filtration control to engineered nanoparticles using the Harvard Versatile Engineered Nanomaterial Generation System (VENGES). J Nanopart Res 14:812
Tsai S-J, White D, Rodriguez H, Munoz C, Huang CC, Huang CY, Tsai C, Barry C, Ellenbecker M (2012b) Exposure assessment and engineering control approach to airborne nanoparticle: emission from of nanocomposite compounding. J Nanopart Res 14(7):989
Wolff RK, Henderson RF, Eidson AF, Pickrell JA, Rothenberg SJ, Hahn FF (1988) Toxicity of gallium oxide particles following a 4-week inhalation exposure. J Appl Toxicol 8:191–199
Yeganeh B, Kull CM, Hull MS, Marr LC (2008) Characterization of airborne particles during production of carbonaceous nanomaterials. Environ Sci Technol 42(12):4600–4606
Zhang Q, Kusaka Y, Donaldson K (2000) Comparative pulmonary responses caused by exposure to standard cobalt and ultrafine cobalt. J Occup Health 42(2):179–184
Acknowledgments
The authors would like to acknowledge the support and cooperation from the management and staff of the study sites. The authors wish to thank Daniel Almaguer, Isaac Bartholomew, and Chun-Chia Huang for their assistance with field study and data analysis. The authors are also grateful to Kevin L. Dunn, Catherine Beaucham, Appavoo Rengasamy, Cathy Rotunda, Ellen Galloway, and Michael Gressel for their insightful comments and suggestions on the early version of the manuscript. This research was funded by the National Institute for Occupational Safety and Health under the Nanotechnology Research Center Project 927ZJLR.
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Lo, LM., Tsai, C.SJ., Dunn, K.H. et al. Performance of particulate containment at nanotechnology workplaces. J Nanopart Res 17, 435 (2015). https://doi.org/10.1007/s11051-015-3238-4
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DOI: https://doi.org/10.1007/s11051-015-3238-4