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A New Fluorene–Based Fluorescent Probe for Recognition of Hypochlorite Ions and its Applications

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Abstract

Oxidative stress is a trigger for many diseases and occurs with the unstable hypochlorite (ClO−), known as one of the reactive oxygen species (ROS) in organisms. Then, HOCI is acknowledged as an oxidizing species that eliminates a variety of environmental pollutants. Hence, the development of novel methodologies for the selective and precise identification of HOCl/ ClO− is considered to be of utmost importance. In this study, the design, characterization, and applications of a fluorene-based fluorescent probe (FHBP) dependent on the ESIPT mechanism with a "turn-on" response for the sensitive/selective determination of ClO− against other competing samples were reported. The experimental results indicated that the detection limit for ClO−could be quantitatively determined by the probe to be 8.2 × 10−7 M. The binding constant of the probe FHBP with ClO− was computed as 9.75 × 103 M−1. In addition, the response time of FHBP was appointed to be 30 s, indicating a rapid reaction with ClO−. It has also been demonstrated that this probe can be successfully used for the detection of ClO− on filter papers, TLC sheets, cotton swabs, and real samples.

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Acknowledgements

This research was financially supported by Karamanoglu Mehmetbey University.

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  1. Department of Chemistry, Kamil Ozdag Science Faculty, Karamanoglu Mehmetbey University, 70100, Karaman, Turkey

    Tahir Savran

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Savran, T. A New Fluorene–Based Fluorescent Probe for Recognition of Hypochlorite Ions and its Applications. J Fluoresc (2024). https://doi.org/10.1007/s10895-024-03702-z

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