Abstract
Purpose
The aim of the study is to evaluate the effects of diabetic retinopathy and intravitreal injections on the corneal, limbal and scleral areas.
Methods
Patients with diabetes mellitus at different diagnosis and treatment levels were compared among themselves and with the control group in terms of corneal, limbal and scleral aspects with the help of anterior segment optical coherence tomography. In addition, clinical tests such as tear break-up time, Schirmer test-I and ocular surface disease index questionnaire were applied to the patients and the difference between the groups was investigated.
Results
When the groups were examined in terms of BUT, SCH-I and OSDI, there was a statistically significant difference between control group and diabetic group(p < 0.05). In the limbal region, all measurements are higher than in patients with diabetic eye involvement. Thinning was detected in the scleral area with intravitreal injection (p < 0.05).
Conclusion
It should be known that DM may cause undesirable changes in the limbal region, and the importance of non-invasive detection with AS-OCT should not be forgotten. Since intravitreal injections for DME cause thinning of the sclera, it can cause various complications, and it may be recommended to change the quadrant in repetitive injection applications.
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All data generated or analyzed during this study are included in this manuscript.
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ACÇ and AKÇ wrote the manuscript and prepared tables and figures. HG supervised all process.
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Çınar, A.C., Küpeli Çınar, A. & Güçlü, H. Evaluation of the effect of intravitreal injections on corneal epithelial, scleral and limbal region changes in diabetic retinopathy by AS-OCT. Int Ophthalmol 44, 31 (2024). https://doi.org/10.1007/s10792-024-02947-8
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DOI: https://doi.org/10.1007/s10792-024-02947-8