Skip to main content

Advertisement

Log in

Factors affecting pain in patients undergoing bilateral cataract surgery

  • Original Paper
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To compare the perceived pain and estimated operative duration among patients undergoing bilateral cataract surgery and to demonstrate correlations with the surgical interval and the demographic and medical characteristics of the patients.

Methods

A total of 466 patients with cataract who underwent ocular surgery were included. The patients estimated the perceived operative duration and pain they felt during the operation at two times, immediately after surgery and on the first postoperative day; pain was scored using a visual analog scale ranging from 0 (no pain) to 10 (unbearable pain). Patients undergoing bilateral surgeries were divided into four subgroups based on the interval between the two operations (1, 2, 4, or 6 weeks). The perceived pain score and the estimated operative duration were the primary outcomes.

Results

The pain scores were higher for the second surgery than for the first surgery both immediately after surgery (P = 0.043) and on the first postoperative day (P = 0.002). The estimated operative duration was longer for the second surgery (P = 0.001). Only patients who underwent the second surgery at an interval of 2 weeks perceived more pain both immediately and 1 day postoperatively (P = 0.002, P = 0.022) and a longer operative duration (P < 0.001). Gender, age, and education level might also influence the pain score.

Conclusions

Female patients, patients with a younger age, and patients with higher education level are likely to report more pain. Patients who require bilateral cataract surgery should not undergo the second surgery before an interval of 2 weeks.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Data sharing statement

The total data of the study could be got on the ResMan platform (www.medresman.org) for 5 years (from 2018 to 2023).

References

  1. Pascolini D, Mariotti SP (2012) Global estimates of visual impairment: 2010. Br J Ophthalmol 96:614–618

    Article  Google Scholar 

  2. Ursea R, Feng MT, Zhou M, Lien V, Loeb R (2011) Pain perception in sequential cataract surgery: comparison of first and second procedures. J Cataract Refract Surg 37:1009–1014

    Article  Google Scholar 

  3. Adatia FA, Munro M, Jivraj I, Ajani A, Braga-Mele R (2015) Documenting the subjective patient experience of first versus second cataract surgery. J Cataract Refract Surg 41:116–121

    Article  Google Scholar 

  4. Akkaya S, Özkurt YB, Aksoy S, Kökçen HK (2017) Differences in pain experience and cooperation between consecutive surgeries in patients undergoing phacoemulsification. Int Ophthalmol 37:545–552

    Article  Google Scholar 

  5. Sharma N, Ooi J, Figueira E et al (2007) Patient perceptions of second eye clear corneal cataract surgery using assisted topical anaesthesia. Eye 22:547–550

    Article  Google Scholar 

  6. Bardocci A, Ciucci F, Lofoco G, Perdicaro S, Lischetti A (2011) Pain during second eye cataract surgery under topical anesthesia: an intraindividual study. Graefe’s Arch Clin Exp Ophthalmol 249:1511–1514

    Article  CAS  Google Scholar 

  7. Hari-Kovacs A, Lovas P, Facsko A, Crate ID (2012) Is second eye phacoemulsification really more painful? Wien Klin Wochenschr 124:516–519

    Article  Google Scholar 

  8. Aslankurt M, Aslan L, Başkan AM et al (2014) Pain and cooperation in patients having dominant-side or nondominant-side phacoemulsification. J Cataract Refract Surg 40:199–202

    Article  Google Scholar 

  9. Yu J, Ye T, Huang Q et al (2016) Comparison between subjective sensations during first and second phacoemulsification eye surgeries in patients with bilateral cataract. J Ophthalmol 2016:1–6

    Google Scholar 

  10. Johnston RL, Whitefield LA, Giralt J et al (1998) Topical versus peribulbar anesthesia, without sedation, for clear corneal phacoemulsification. J Cataract Refract Surg 24:407

    Article  CAS  Google Scholar 

  11. Omulecki W, Laudanska-Olszewska I, Synder A (2009) Factors affecting patient cooperation and level of pain perception during phacoemulsification in topical and intracameral anesthesia. Eur J Ophthalmol 19:977–983

    Article  Google Scholar 

  12. Edwards RR, Goble L, Kwan A et al (2006) Catastrophizing, pain, and social adjustment in scleroderma: relationships with educational level. Clin J Pain 22:639–646

    Article  Google Scholar 

  13. Lofoco G, Ciucci F, Bardocci A et al (2008) Efficacy of topical plus intracameral anesthesia for cataract surgery in high myopia: randomized controlled trial. J Cataract Refract Surg 34:1664–1668

    Article  Google Scholar 

  14. Wilbrandt HR, Wilbrandt TH (1994) Pathogenesis and management of the lens-iris diaphragm retropulsion syndrome during phacoemulsification. J Cataract Refr Surg 20:48

    Article  CAS  Google Scholar 

  15. Eke T, Thompson JR (2007) Serious complications of local anaesthesia for cataract surgery: a 1 year national survey in the United Kingdom. Br J Ophthalmol 91:470–475

    Article  Google Scholar 

  16. Khezri MB, Merate H (2013) The effects of melatonin on anxiety and pain scores of patients, intraocular pressure, and operating conditions during cataract surgery under topical anesthesia. Indian J Ophthalmol 61:319–324

    Article  Google Scholar 

  17. Jacobi PC, Dietlein TS, Jacobi FK (2000) A comparative study of topical vs retrobulbar anesthesia in complicated cataract surgery. Arch Ophthalmol 118:1037–1043

    Article  CAS  Google Scholar 

  18. Zhao L, Zhu H, Zhao P, Wu Q, Hu Y (2012) Topical anesthesia versus regional anesthesia for cataract surgery: a meta-analysis of randomized controlled trials. Ophthalmology 119:659–667

    Article  Google Scholar 

  19. Jiang L, Zhang K, He W et al (2015) Perceived pain during cataract surgery with topical anesthesia: a comparison between first-eye and second-eye surgery. J Ophthalmol 2015:383456

    PubMed  PubMed Central  Google Scholar 

  20. Zhu X, Wolff D, Zhang K et al (2015) Molecular inflammation in the contralateral eye after cataract surgery in the first eye. Investig Ophthalmol Vis Sci 56:5566

    Article  Google Scholar 

  21. Zhang Y, Du Y, Jiang Y, Zhu X, Lu Y (2018) Effects of pranoprofen on aqueous humor monocyte chemoattractant protein-1 level and pain relief during second-eye cataract surgery. Front Pharmacol 9:783

    Article  Google Scholar 

  22. Belmonte C, Acosta MC, Schmelz M, Gallar J (1999) Measurement of corneal sensitivity to mechanical and chemical stimulation with a CO2 esthesiometer. Investig Ophthalmol Vis Sci 40:513

    CAS  Google Scholar 

  23. Müller LJ, Marfurt CF, Kruse F, Tervo TMT (2003) Corneal nerves: structure, contents and function. Exp Eye Res 76:521–542

    Article  Google Scholar 

  24. Leonardi A (2002) The central role of conjunctival mast cells in the pathogenesis of ocular allergy. Curr Allergy Asthma Rep 2:325–331

    Article  Google Scholar 

  25. Oetjen LK, Mack MR, Feng J et al (2017) Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch. Cell 171:217–228

    Article  CAS  Google Scholar 

  26. Huang CC, Yang W, Guo C et al (2018) Anatomical and functional dichotomy of ocular itch and pain. Nat Med 24:1268–1276

    Article  CAS  Google Scholar 

  27. Sugita S, Taguchi C, Takase H et al (2000) Soluble Fas ligand and soluble Fas in ocular fluid of patients with uveitis. Br J Ophthalmol 84:1130–1134

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We would like to thank all the patients enrolled in the trial and the nurses’ patience for those patients more painful.

Funding

The study was funded by the National Natural Science Foundation of China (No. 81870647).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Rongdi Yuan or Jian Ye.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the ethics committee of the Third Affiliated Hospital of Army Medical University and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (PDF 61 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, P., Zhang, S., Geng, Z. et al. Factors affecting pain in patients undergoing bilateral cataract surgery. Int Ophthalmol 40, 297–303 (2020). https://doi.org/10.1007/s10792-019-01178-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-019-01178-6

Keywords

Navigation