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Chemical modification, characterization and bioactivity of a released exopolysaccharide (r-EPS1) from Lactobacillus plantarum 70810

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Abstract

In the present study, a released exopolysaccharide (r-EPS1) from L. plantarum 70810 was modified by acetylation, phosphorylation and carboxymethylation. Scanning electron micrograph (SEM) and thermogravimetric analysis (TGA) showed the r-EPS1 derivatives had different surface morphology and thermal behavior. Compared with r-EPS1, the derivatives exhibited stronger antioxidant and antitumor activities. The study provided experimental evidences that chemical modification could be an effective way to improve the bioactivity of exopolysaccharide from L. plantarum 70810. It is noted that these derivatives could be explored as novel potential antioxidant and antitumor agents.

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Acknowledgments

This work was co-financed by Specialized Research Fund for the Doctoral Program of Higher Education of China (No. 20130097110022), National Natural Science Foundation of China (No. 31371807; 31201422), Graduate Student Scientific Research Innovation Project of Jiangsu Normal University (No. CXZZ13_0285), and was also supported by the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD).

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  1. College of Food Science and Technology, Nanjing Agricultural University, 1 Weigang Road, Nanjing, Jiangsu, People’s Republic of China

    Kun Wang, Wei Li, Xin Rui, Teng Li, Xiaohong Chen, Mei Jiang & Mingsheng Dong

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  1. Kun Wang
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  2. Wei Li
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  3. Xin Rui
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Correspondence to Mingsheng Dong.

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Wang, K., Li, W., Rui, X. et al. Chemical modification, characterization and bioactivity of a released exopolysaccharide (r-EPS1) from Lactobacillus plantarum 70810. Glycoconj J 32, 17–27 (2015). https://doi.org/10.1007/s10719-014-9567-1

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