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Tetrahydroazepines with an annulated five-membered heteroaromatic ring

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Chemistry of Heterocyclic Compounds Aims and scope

The review summarizes and analyzes the literature data on the synthetic design of promising biologically active hydrogenated furo-, thieno-, pyrrolo-, and azoloazepine systems. The information is systematized according to the principle of prevalence and significance of the employed synthetic methods: annulation of an azepine ring to a five-membered heteroaromatic ring, annulation of a five-membered heteroaromatic ring to an azepine ring, ring expansion reactions of hetaro-annulated cyclohexanones and piperidines. The bibliography of the review contains 94 sources published in 2000–2022.

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  1. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Akademika Kukhara St., Kyiv, 02094, Ukraine

    Ivanna Yu. Danyliuk & Mykhailo V. Vovk

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Correspondence to Ivanna Yu. Danyliuk.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2022, 58(11), 567–581

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Danyliuk, I.Y., Vovk, M.V. Tetrahydroazepines with an annulated five-membered heteroaromatic ring. Chem Heterocycl Comp 58, 567–581 (2022). https://doi.org/10.1007/s10593-022-03131-5

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