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Synthesis of new types of pyrrolo/pyrido[1,2-a][1,3]diazepines based on seven-membered ring HKA via a one-pot three-component reaction

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Abstract

An efficient one-pot synthesis of new types of pyrrolo/pyrido[1,2-a][1,3]diazepines by using the seven-membered ring HKA, an activated methylene compound, and either arylglyoxal monohydrates or salicylaldehyde is described. This method has the advantages of mild reaction conditions and absence of catalyst and provides an entry point to pyrrolo/pyrido and diazepine ring structures.

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Acknowledgements

Financial support of this research from Imam Khomeini International University, Iran, is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, Imam Khomeini International University, Qazvin, Iran

    Mohammad Bayat & Monireh Rezaei

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  1. Mohammad Bayat
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  2. Monireh Rezaei
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Correspondence to Mohammad Bayat.

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Bayat, M., Rezaei, M. Synthesis of new types of pyrrolo/pyrido[1,2-a][1,3]diazepines based on seven-membered ring HKA via a one-pot three-component reaction. J IRAN CHEM SOC 15, 769–777 (2018). https://doi.org/10.1007/s13738-017-1275-x

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  • DOI: https://doi.org/10.1007/s13738-017-1275-x

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