Abstract
Enzymes play a crucial role in various industrial sectors. These biocatalysts not only ensure sustainability and safety but also enhance process efficiency through their unique specificity. Lipases possess versatility as biocatalysts and find utilization in diverse bioconversion reactions. Presently, microbial lipases are gaining significant focus owing to the rapid progress in enzyme technology and their widespread implementation in multiple industrial procedures. This updated review presents new knowledge about various origins of microbial lipases, such as fungi, bacteria, and yeast. It highlights both the traditional and modern purification methods, including precipitation and chromatographic separation, the immunopurification technique, the reversed micellar system, the aqueous two-phase system (ATPS), and aqueous two-phase flotation (ATPF), moreover, delves into the diverse applications of microbial lipases across several industries, such as food, vitamin esters, textile, detergent, biodiesel, and bioremediation. Furthermore, the present research unveils the obstacles encountered in employing lipase, the patterns observed in lipase engineering, and the application of CRISPR/Cas genome editing technology for altering the genes responsible for lipase production. Additionally, the immobilization of microorganisms’ lipases onto various carriers also contributes to enhancing the effectiveness and efficiencies of lipases in terms of their catalytic activities. This is achieved by boosting their resilience to heat and ionic conditions (such as inorganic solvents, high-level pH, and temperature). The process also facilitates the ease of recycling them and enables a more concentrated deposition of the enzyme onto the supporting material. Consequently, these characteristics have demonstrated their suitability for application as biocatalysts in diverse industries.
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References
Abdella B, Youssif AM, Sabry S, Ghozlan HA (2023) Production, purification and characterization of cold-adaptive lipase from the psychrotroph Pseudomonas sp. A6. Braz J Microbiol 54:1623–1633. https://doi.org/10.1007/s42770-023-01079-y
Abou Taleb M, Gomaa SK, Wahba MI, Zaki RA, El-Fiky AF, El-Refai HA, El-Sayed H (2022) Bioscouring of wool fibres using immobilized thermophilic lipase. Int J Biol Macromol 194:800–810. https://doi.org/10.1016/j.ijbiomac.2021.11.128
Adetunji AI, Olaniran AO (2021) Production strategies and biotechnological relevance of microbial lipases: a review. Braz J Microbiol 52:1257–1269. https://doi.org/10.1007/s42770-021-00503-5
Adio OQ, Kareem SO, Osho MB, Omemu AM (2021) Production of lipases in solid-state fermentation by Aspergillus niger F7-02 with agricultural residues. J Microbiol Biotechnol Food Sci 2021:509–512. https://doi.org/10.15414/jmbfs.2015.4.6.509-512
Aghaei H, Yasinian A, Taghizadeh A (2021) Covalent immobilization of lipase from Candida rugosa on epoxy-activated cloisite 30B as a new heterofunctional carrier and its application in the synthesis of banana flavor and production of biodiesel. Int J Biol Macromol 178:569–579. https://doi.org/10.1016/j.ijbiomac.2021.02.146
Agobo KU, Arazu VA, Uzo K, Igwe CN (2017) Microbial lipases: a prospect for biotechnological industrial catalysis for green products: a review. Ferment Technol 6:2–13. https://doi.org/10.4172/2167-7972.1000144
Ahmad R, Sardar M (2015) Enzyme immobilization: an overview on nanoparticles as immobilization matrix. Biochem Analyt Biochem 4:1–8. https://doi.org/10.4172/2161-1009.1000178
Alami NH, Nasihah L, Umar RLA, Kuswytasari ND, Zulaika E, Shovitri M (2017) Lipase production in lipolytic yeast from Wonorejo mangrove area. In: AIP Conference Proceedings, vol 1854. AIP Publishing LLC. https://doi.org/10.1063/1.4985392
Alawiah A, Sayied FS, Hamsharg OM (2023) Detection and molecular characterization of lipase-producing bacteria. Egyptian Pharm J 22:54–65
Alexandre JYNH, Cavalcante FTT, Freitas LM, Castro AP, Borges PT, de Sousa PG et al (2022) A Theoretical and Experimental study for enzymatic biodiesel production from Babassu oil (Orbignya sp.) using Eversa lipase. Catalysts 12:1322–1342. https://doi.org/10.3390/catal12111322
Alonazi M, Al-Diahan SK, Alzahrani ZRA, Bacha AB (2023) Combined immobilized lipases for effective biodiesel production from spent coffee grounds. Saudi J Biol Sci 30:103772–103790. https://doi.org/10.1016/j.sjbs.2023.103772
Ameri A, Shakibaie M, Faramarzi MA, Ameri A, Amirpour-Rostami S, Rahimi HR, Forootanfar H (2017) Thermoalkalophilic lipase from an extremely halophilic bacterial strain Bacillus atrophaeus FSHM2: Purification, biochemical characterization and application. Biocatal Biotransform 35:151–160. https://doi.org/10.1080/10242422.2017.1308494
Amini Z, Ong HC, Harrison MD, Kusumo F, Mazaheri H, Ilham Z (2017) Biodiesel production by lipase-catalyzed transesterification of Ocimum basilicum L. (sweet basil) seed oil. Energy Convers Manag 132:82–90. https://doi.org/10.1016/j.enconman.2016.11.017
Angajala G, Pavan P, Subashini R (2016) Lipases: an overview of its current challenges and prospects in the revolution of biocatalysis. Biocatal Agric Biotechnol 16:257–270. https://doi.org/10.1016/j.bcab.2016.07.001
Asmat S, Anwer AH, Husain Q (2019) Immobilization of lipase onto novel constructed polydopamine grafted multiwalled carbon nanotube impregnated with magnetic cobalt and its application in synthesis of fruit flavours. Int J Biol Macromol 140:484–495. https://doi.org/10.1016/j.ijbiomac.2019.08.086
Astrup A, Magkos F, Bier D, Brenna J, de Oliveira OM, Hill J, King J, Mente A, Ordovas J, Volek J et al (2020) Saturated fats and health: a reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review. J Am Coll Cardiol 76:844–857. https://doi.org/10.1016/j.jacc.2020.05.077
Athar M, Zaidi S, Hassan S (2020) Intensification and optimization of biodiesel production using microwave-assisted acid-organo catalyzed transesterification process. Sci Rep 10:21239–21257. https://doi.org/10.1038/s41598-020-77798-1
Bahari A, Akoh C (2018a) Synthesis of a cocoa butter equivalent by enzymatic interesterification of illipe butter and palm midfraction. J Am Oil Chem Soc 95:547–555. https://doi.org/10.1002/aocs.12083
Bahari A, Akoh C (2018b) Texture, rheology and fat bloom study of ‘chocolates’ made from cocoa butter equivalent synthesized from illipe butter and palm mid-fraction. LWT 97:349–354. https://doi.org/10.1016/j.lwt.2018.07.013
Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Durjava MF, Kouba M, López-Alonso M, López Puente S, Marcon F et al (2021) Assessment of a feed additive consisting of all-rac-alpha-tocopheryl acetate (vitamin E) for all animal species for the renewal of its authorisation (DSM). EFSA J 19:6529–6543. https://doi.org/10.2903/j.efsa.2021.6529
Basso A, Serban S (2019) Industrial application of immobilization enzymes. Mol Catal 479:110607–110627. https://doi.org/10.1016/j.mcat.2019.110607
Bayramoglu G, Celikbicak O, Kilic M, Arica MY (2022) Immobilization of Candida rugosa lipase on magnetic chitosan beads and application in flavor esters synthesis. Food Chem 366:130699. https://doi.org/10.1016/j.foodchem.2021.130699
Behera S, Das S, Balasubramanian S (2021) An atomistic view of solvent-free protein liquids: the case of Lipase A. Phys Chem Chem Phys 23:7302–7312. https://doi.org/10.1039/D0CP05964A
Bharathi D, Rajalakshmi G (2019) Microbial lipases: an overview of screening, production and purification. Biocatal Agric Biotechnol 22:101368. https://doi.org/10.1016/j.bcab.2019.101368
Bharathi D, Rajalakshmi G, Komathi S (2019) Optimization and production of lipase enzyme from bacterial strains isolated from petrol spilled soil. J King Saud Univ-Sci 31:898–901. https://doi.org/10.1016/j.jksus.2017.12.018
Bhosale H, Shaheen U, Kadam T (2016) Characterization of a hyperthermostable alkaline lipase from Bacillus sonorensis 4R. Enzyme Res 2016:4170684. https://doi.org/10.1155/2016/4170684
Bi P-y, Li DQ, Dong HR (2009) A novel technique for the separation and concentration of penicillin G from fermentation broth: aqueous two-phase flotation. Sep Purif Technol 69:205–209. https://doi.org/10.1016/j.seppur.2009.07.019
Bilal M, Hussain N, Américo-Pinheiro JHP, Almulaiky YQ, Iqbal HM (2021) Multi-enzyme co-immobilized nano-assemblies: bringing enzymes together for expanding bio-catalysis scope to meet biotechnological challenges. Int J Biol Macromol 186:735–749. https://doi.org/10.1016/j.ijbiomac.2021.07.064
Bilal M, IqbaL HMN (2019) State-of-the-art strategies and applied perspectives of enzyme biocatalysis in food sector—current status and future trends. Crit Rev Food Sci Nutr 60:2052–2066. https://doi.org/10.1080/10408398.2019.1627284
Binhayeeding N, Klomklao S, Prasertsan P, Sangkharak K (2020) Improvement of biodiesel production using waste cooking oil and applying single and mixed immobilised lipases on polyhydroxyalkanoate. Renew Energy 162:1819–1827. https://doi.org/10.1016/j.renene.2020.10.009
Blandón LM, Marín MA, Quintero M, Jutinico-Shubach LM, Montoya-Giraldo M, Santos-Acevedo M, Gómez-León J (2022) Diversity of cultivable bacteria from deep-sea sediments of the Colombian Caribbean and their potential in bioremediation. Antonie Van Leeuwenhoek 115:421–431. https://doi.org/10.1007/s10482-021-01706-4
Boutillier S, Fourmentin S, Laperche B (2020) Food additives and the future of health: an analysis of the ongoing controversy on titanium dioxide. Futures 122:102598. https://doi.org/10.1016/j.futures.2020.102598
Brigida AIS, Buarque FS, Nogueira VLR et al (2023) Partial purification of crude lipase extract from Yarrowia lipolytica: precipitation, aqueous two-phase system and immobilization methods. Cleaner Chem Eng 6:100105. https://doi.org/10.1016/j.clce.2023.100105
Burdge G, Calder P (2015) Introduction to fatty acids and lipids. World Rev Nutr Diet 112:1–16. https://doi.org/10.1159/000365423
Busso D, David A, Penailillo R, Echeverría G, Rigotti A, Kovalskys I, Gómez G, Cortés Sanabria LY, Yépez García MC, Pareja RG et al (2021) Intake of vitamin E and C in women of reproductive age: results from the Latin American study of nutrition and health. Nutrients 13:1954. https://doi.org/10.3390/nu13061954
Caritá A, Fonseca B, Shultz J, Michniak B, Chorilli M, Leonardi G (2020) Vitamin C: one compound, several uses. Advances for delivery, efficiency and stability. Nanomed Nanotechnol Biol Med 24:102117. https://doi.org/10.1016/j.nano.2019.102117
Carocho M, Barreiro M, Morales P, Ferreira I (2014) Adding molecules to food, pros and cons: a review on synthetic and natural food additives. Compr Rev Food Sci Food Saf 13:377–399. https://doi.org/10.1111/1541-4337.12065
Casas L, Gasteazoro F, Duquesne S, Bordes F, Marty A, Sandoval G (2018) Lipases: an overview. In: Sandoval G (ed) Lipases and phospholipases: methods and protocols. Springer New York, New York, NY, USA, pp 3–38. https://doi.org/10.1007/978-1-61779-600-5_1
Castilla A, Giordano SR, Irazoqui G (2022) Extremophilic lipases and esterases: characteristics and industrial applications. In: Microbial extremozymes. Elsevier, Amsterdam, The Netherlands, pp 207–222. https://doi.org/10.1016/B978-0-12-822945-3.00001-4
Chalupka J, Jacek D, Adam S et al (2023) The application of two-phase catalytic system in enantioselective separation of racemic (R, S 11-Phenylethanol). Ctalysts 13. https://doi.org/10.3390/catal13020292
Enespa, Chandra P, Singh D (2022) Sources, purification, immobilization and industrial applications of microbial lipases: an overview. Crit Rev Food Sci Nutr 18:6653–6686. https://doi.org/10.1080/10408398.2022.2038076
Chandra P, Singh R, Arora PK (2020) Microbial lipases and their industrial applications: a comprehensive review. Microb Cell Factories 19:169–216. https://doi.org/10.1186/s12934-020-01428-8
Chang SW, Lee GC, Shaw JF (2006) Efficient production of active recombinant Candida rugosa LIP3 lipase in Pichia pastoris and biochemical characterization of the purified enzyme. J Agric Food Chem 54:5831–5838. https://doi.org/10.1021/jf060835e
Chapman J, Ismail AE, Dinu CZ (2018) Industrial applications of enzymes: recent advances, techniques, and outlooks. Catalysts 8:238. https://doi.org/10.3390/catal8060238
Chen D, Li B, Li B, Zhang X, Wei L, Zheng W (2019) Synthesis of vitamin E succinate catalyzed by nano-SiO2 immobilized DMAP derivative in mixed solvent system. Green Process Synth 8:667–676. https://doi.org/10.1515/gps-2019-0037
Chen H, Yu F, Shi N, Du P, Liu S, Zhang X, Tan J (2021) Overexpression and mutation of a novel lipase from Serratia marcescens L1 in Escherichia coli. Process Biochem 111:233–240. https://doi.org/10.1016/j.procbio.2021.11.001
Coelho ALS, Orlandelli RC (2021) Immobilized microbial lipases in the food industry: a systematic literature review. Crit Rev Food Sci Nutr 61:1689–1703. https://doi.org/10.1080/10408398.2020.1764489
Corovie M, Milivojeric A, Simovic M, Banjanea K et al (2020) Enzymatically derived oil-based L-ascorbyl esters: synthesis, antioxidant, properties and controlled release from cosmetic formulation. Sustainable Chem Pharm 15:100231. https://doi.org/10.1016/j.scp.2020.100231
Costa MJ, Silva MR, Ferreira EE, Carvalho AK, Basso RC, Pereira EB et al (2020) Enzymatic biodiesel production by hydroesterification using waste cooking oil as feedstock. Chem Eng Process 157:108131. https://doi.org/10.1016/j.cep.2020.108131
Cumming H, Marshall SN (2021) Lipase-catalysed synthesis of mono- and di-acyl esters of glyceryl caffeate in propylene carbonate and their antioxidant properties in tuna oil. J Biotechnol 325:217–225. https://doi.org/10.1016/j.jbiotec.2020.10.021
Dai Y, Tyl C (2021) A review on mechanistic aspects of individual versus combined uses of enzymes as clean label-friendly dough conditioners in breads. J Food Sci 86:1583–1598. https://doi.org/10.1111/1750-3841.15713
Davani D, Negahdaripour M, Karimzadeh I, Seifan M, Mohkam M, Masoumi S, Berenjian A, Ghasemi Y (2019) Prebiotics: definition, types, sources, mechanisms, and clinical applications. Foods 8:92–116. https://doi.org/10.3390/foods8030092
de Alencar Figueira Angelotti J, Battaglia Hirata D, Rodrigues dos Santos M (2022) Lipases: sources of acquisition, ways of production, and recent applications. Catal Res 2:35–78. https://doi.org/10.21926/cr.2202013
de Araújo M, Franco Y, Messias M, Longato G, Pamphile J, Carvalho P (2017) Biocatalytic synthesis of flavonoid esters by lipases and their biological benefits. Planta Med 83:7–22. https://doi.org/10.1055/s-0042-118883
De la Fuente M, Sánchez C, Vallejo C, Díaz E, Arnalich F, Hernanz Á (2020) Vitamin C and vitamin C plus E improve the immune function in the elderly. Exp Gerontol 142:111118. https://doi.org/10.1016/j.exger.2020.111118
Deb C, Daniel J, Sirakova TD, Abomoelak B, Dubey VS, Kolattukudy PE (2006) A novel lipase belonging to the hormone-sensitive lipase family induced under starvation to utilize stored triacylglycerol in Mycobacterium tuberculosis. J Biol Chem 281:3866–3875. https://doi.org/10.1074/jbc.M505556200
Demera LL, Barahona PP, Barriga EJC (2019) Production, extraction and characterization of lipases from the antarctic yeast Guehomyces pullulans. Am J Biochem Biotechnol 15:75–82. https://doi.org/10.3844/ajbbsp.2019.75.82
Diamanti E, Papalou O, Kandaraki E, Kassi G (2017) Mechanisms in endocrinology: nutrition as a mediator of oxidative stress in metabolic and reproductive disorders in women. Eur J Endocrinol 176:R79–R99
Díaz Z, Menghi K, Guerrero M, Nocelli N, Fanani M (2020) l-Ascorbic acid alkyl esters action on stratum corneum model membranes: an insight into the mechanism for enhanced skin permeation. Colloids Surf B Biointerfaces 185:110621. https://doi.org/10.1016/j.colsurfb.2019.110621
dos Santos LN, Perna RF, Vieira AC, de Almeida AF, Ferreira NR (2023) Trends in the use of lipases: a systematic review and bibliometric analysis. Foods 12:3058. https://doi.org/10.3390/foods12163058
Duman-Özdamar ZE, Binay B (2021) Production of industrial enzymes via Pichia pastoris as a cell factory in bioreactor: current status and future aspects. Protein J 40:367–376. https://doi.org/10.1007/s10930-021-09968-7
Durazzo A, Lucarini M, Santini A (2020) Nutraceuticals in human Health. Foods 9:370. https://doi.org/10.3390/foods9030370
Dutta S, Ray L (2009) Production and characterization of an alkaline thermostable crude lipase from an isolated strain of Bacillus cereus C 7. Appl Biochem Biotechnol 159:142–154. https://doi.org/10.1007/s12010-009-8543-x
El-Fiky AF, Khalil EM, Mowafi S, Zaki RA, El-Sayed H (2022) A novel approach towards removal of lipid barrier from wool fibers’ surface using thermophilic lipase. J Nat Fibers 19:9471–9485. https://doi.org/10.1080/15440478.2021.1982835
El-Gendi H, Saleh AK, Badierah R, Redwan EM, El-Maradny YA, El-Fakharany EM (2022) A comprehensive insight into fungal enzymes: structure, classification, and their role in mankind’s challenges. J Fungi 8:23. https://doi.org/10.3390/jof8010023
Elyasifar B, Sajadi F, Nazemiyeh H, Mehdizadeh Mogham E (2023) Study of hydrolytic enzymes activity and stability of the isolated yeast close to Zygoascus hellenicus. Curr Biotechnol 12:118–128. https://doi.org/10.2174/2211550112666230503142402
Ezema BO, Omeje KO, Bill RM, Goddard ADO, Eze SO, Fernandez-Castane A (2022) Bioinformatic characterization of a triacylglycerol lipase produced by Aspergillus flavus isolated from the decaying seed of Cucumeropsis mannii. J Biomol Struct Dyn 2022:1–15. https://doi.org/10.1080/07391102.2022.2035821
Fan Y, Su F, Li K, Ke C, Yan Y (2017) Carbon nanotube filled with magnetic iron oxide and modified with polyamidoamine dendrimers for immobilizing lipase toward application in biodiesel production. Sci Rep 7:45643. https://doi.org/10.1038/srep45643
Farooq S, Abdullah ZH, Weiss J (2021) A comprehensive review on polarity, partitioning, and interactions of phenolic antioxidants at oil-water interface of food emulsions. Compr Rev Food Sci Food Saf 20:4250–4277. https://doi.org/10.1111/1541-4337.12792
Fatima S, Faryad A, Ataa A, Joyia FA, Parvaiz A (2021) Microbial lipase production: a deep insight into the recent advances of lipase production and purification techniques. Biotechnol Appl Biochem 68:445–458. https://doi.org/10.1002/bab.2019
Fernandes MLM, Krieger N, Baron AM, Zamora PP, Ramos LP, Mitchell DA (2004) Hydrolysis and synthesis reactions catalysed by Thermomyces lanuginosa lipase in the AOT/Isooctane reversed micellar system. J Mol Catal B Enzym 30:43–49. https://doi.org/10.1016/j.molcatb.2004.03.004
Ferreira S, Osório N, Tecelão C (2022) 9-Bioprocess technologies for production of structured lipids as nutraceuticals. In: Rai AK, Singh SP, Pandey A, Larroche C, Soccol CR (eds) Current developments in biotechnology and bioengineering. Elsevier, Amsterdam, The Netherlands, pp 209–237
Filho DG, Silva AG, Guidini CZ (2019) Lipases: sources, immobilization methods, and industrial applications. Appl Microbiol Biotechnol 103:7399–7423. https://doi.org/10.1007/s00253-019-10027-6
Fitri RD, Illavi G (2022) Expression of recombinant lipase from Serratia marcescens LII61 in Escherichia coli. Jordan J Biol Sci 15:199–203. https://doi.org/10.54319/jjbs/150206
Gaikaiwari RP, Wagh SA, Kulkarni BD (2012) Efficient lipase purification using reverse micellar extraction. Bioresour Technol 108:224–230. https://doi.org/10.1016/j.biortech.2011.11.126
Gammone M, Riccioni G, Parrinello G, D’Orazio N (2018) Omega-3 polyunsaturated fatty acids: benefits and endpoints in sport. Nutrients 11:46. https://doi.org/10.3390/nu11010046
García-Silvera EE, Martínez-Morales F, Bertrand B, Morales-Guzmán D, Rosas-Galván NS, León-Rodríguez R et al (2018) Production and application of a thermostable lipase from Serratia marcescens in detergent formulation and biodiesel production. Biotechnol Appl Biochem 65:156–172. https://doi.org/10.1002/bab.1565
Geoffry K, Achur RN (2018) Screening and production of lipase from fungal organisms. Biocatal Agric Biotechnol 14:241–253. https://doi.org/10.1016/j.bcab.2018.03.009
Gill B, Indyk H (2020) Separation of RRR-α-tocopherol by chiral chromatography. J AOAC Int 103:1288–1292. https://doi.org/10.1093/jaoacint/qsaa055
Giménez T, Mula D, Gea S, Martínez M, Martí N, Valero M, Saura D (2019) Lipase catalyzed deacidification of tocopherol-rich distillates obtained from natural vitamin E sources. Process Biochem 77:70–76. https://doi.org/10.1016/j.procbio.2018.11.008
Giraldo L, Gómez-Granados F, Moreno-Piraján JC (2023) Biodiesel production using palm oil with a MOF-lipase B biocatalyst from Candida antarctica: a kinetic and thermodynamic study. Int J Mol Sci 24:10741. https://doi.org/10.3390/ijms241310741
Glantz M, Rosenlow M, Lindmark-Mansson H et al (2020) Impact of protease and lipase activities on quality of Swedish raw milk. Int Dairy J 107:104724. https://doi.org/10.1016/j.idairyj.2020.104724
Godoy CA, Klett J, Di Geronimo B, Hermoso JA, Guisán JM, Carrasco-López C (2019) Disulfide engineered lipase to enhance the catalytic activity: a structure-based approach on btl2. Int J Mol Sci 20:5245. https://doi.org/10.3390/ijms20215245
Godoy CA, Pardo-Tamayo JS, Barbosa O (2022) Microbial lipases and their potential in the production of pharmaceutical building blocks. Int J Mol Sci 23:9933. https://doi.org/10.3390/ijms23179933
Gómez A, Escobedo Z, Welti J (2020) Phenolic compounds in Mesoamerican fruits-characterization, health potential and processing with innovative technologies. Int J Mol Sci 21:8357. https://doi.org/10.3390/ijms21218357
Goswami D (2022) Lipase catalysis in mixed micelles. ChemBioEng Rev 9:409–418. https://doi.org/10.1002/cben.202100045
Gricajeva A, Kazlauskas S, Kalediene L, Bendikiene V (2018) Analysis of Aspergillus sp. lipase immobilization for the application in organic synthesis. Int J Biol Macromol 108:1165–1175. https://doi.org/10.1016/j.ijbiomac.2017.11.010
Guan A, Hou Y, Yang R, Qin J (2024) Enzyme engineering for functional lipids synthesis: recent advances and perspective. Bioresour Bioprocess 11:1–23. https://doi.org/10.1186/s40643-023-00723-7
Guimaraes JR et al (2023) A review of lipase immobilization on hydrophobic supports incorporeity systematic mapping principles. React Chem Eng 8:2689. https://doi.org/10.1039/D3RE00420A
Guo Y, Cai Z, Xie Y, Ma A, Zhang H, Rao P, Wang Q (2020) Synthesis, physicochemical properties, and health aspects of structured lipids: a review. Compr Rev Food Sci Food Saf 19:759–800. https://doi.org/10.1111/1541-4337.12537
Hamayun M, Hussain A, Khan SA, Kim HY, Khan AL, Waqas M, Irshad M, Iqbal A, Rehman G, Jan S (2017) Gibberellins producing endophytic fungus Porostereum spadiceum AGH786 rescues growth of salt affected soybean. Front Microbiol 8:686. https://doi.org/10.3389/fmicb.2017.00686
Hammerling U (2016) Retinol as electron carrier in redox signaling, a new frontier in vitamin A research. Hepatobiliary Surg Nutr 5:15–28. https://doi.org/10.3978/j.issn.2304-3881.2016.01.02
Hao Y, Lin Y, Liang S (2018) Efficient expression of Candida ragusa lipase1 in Pichia pastoris and its application for synthesis of vitamin E acetate. Mod Food Sci Technol 34:126–132
Hasan F, Shah AA, Hameed A (2006) Industrial applications of microbial lipases. Enzym Microb Technol 39:235–251. https://doi.org/10.1016/j.enzmictec.2005.10.016
Hasibuan HA, Sitanggang AB, Andarwulan N, Hariyadi P (2021) Enzymatic synthesis of human milk fat substitute—a review on technological approaches. Food Technol Biotechnol 59:475–495. https://doi.org/10.17113/ftb.59.04.21.7205
Hecht ES, Mehta S, Wecksler AT, Aguilar B, Swanson N, Phung W, Dubey Kelsoe A, Benner WH, Tesar D, Kelley RF (2022) Insights into ultra-low affinity lipase-antibody noncovalent complex binding mechanisms. mAbs 14:2135183. https://doi.org/10.1080/19420862.2022.2135183
Helal SE, Abdelhady HM, Abou-Taleb KA, Hassan MG, Amer MM (2021) Lipase from Rhizopus oryzae R1: in-depth characterization, immobilization, and evaluation in biodiesel production. J Genet Eng Biotechnol 19:1–13. https://doi.org/10.1186/s43141-020-00094-y
Holtheuer J, Tavernini L, Bernal C, Romer O et al (2023) Enzymatic synthesis of ascorbyl palmitate in a rotating bed reactor. Molecules 28:644. https://doi.org/10.3390/molecules28020644
Hu L, Wang J, Yang ZH (2023) Countercurrent chromatography separation of vitamin E isomers in a co-current mode. Separation Sci 2300285. https://doi.org/10.1002/jssc.202300285
Huang SM, Li HJ, Liu YC, Kuo CH, Shieh CJ (2017) An efficient approach for lipase-catalyzed synthesis of retinyl laurate nutraceutical by combining ultrasound assistance and artificial neural network optimization. Molecules 22:1972. https://doi.org/10.3390/molecules22111972
Hussain M, Khan I, Jiang B, Zheng L (2023) Lipases: sources, immobilization techniques and application. Int J Environ Agric Biotechnol 8:12–19. https://doi.org/10.22161/ijeab.86.12
Hussain S, Rehman A, Luckett D, Blanchard C, Obied H, Strappe P (2019) Phenolic compounds with antioxidant properties from canola meal extracts inhibit adipogenesis. Int J Mol Sci 21:1. https://doi.org/10.3390/ijms21010001
Hwang HT, Qi F, Yuan C, Zhao X, Ramkrishna D, Liu D et al (2014) Lipase-catalyzed process for biodiesel production: protein engineering and lipase production. Biotechnol Bioeng 111:639–653. https://doi.org/10.1002/bit.25162
Ikram M, Ali N, Jan G, Jan FG, Rahman IU, Iqbal A, Hamayun M (2018) IAA producing fungal endophyte Penicillium roqueforti Thom., enhances stress tolerance and nutrients uptake in wheat plants grown on heavy metal contaminated soils. PLoS ONE 13:e0208150. https://doi.org/10.1371/journal.pone.0208150
Iliemene UDE, Liman ML, Olonishawa PT (2023) Application of lipases and phospholipases in bioremediation of oil-contaminated environment/habitants. In: Phospholipase in physiology and pathology. Academic Press, pp 405–422. https://doi.org/10.1016/B978-0-443-15313-6.00011-9
Illanes A, Cauerhff A, Wilson L, Castro GR (2012) Recent trends in biocatalysis engineering. Bioresour Technol 115:48–57. https://doi.org/10.1016/j.biortech.2011.12.050
Iram D, Riaz R, Iqbal RK (2019) Usage of potential micro-organisms for degradation of plastics. Open J Environ Biol 4:7–15. https://doi.org/10.17352/ojeb.000010
Ismail AR, Kashtoh H, Baek KH (2021) Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: biotechnological approaches and applications. Int J Biol Macromol 187:127–142. https://doi.org/10.1016/j.ijbiomac.2021.07.101
Iuliano M, Sarno M, De Pasquale S, Ponticorvo E (2020) Candida rugosa lipase for the biodiesel production from renewable sources. Renew Energy 162:124–133. https://doi.org/10.1016/j.renene.2020.08.019
Jakob L, Singer J, Nirschl M (2021) Importance of gas input in aqueous two-phase flotation. Chem Eng Sci 233:116391. https://doi.org/10.1016/j.ces.2020.116391
Javed S, Azeem F, Hussain S, Rasul I, Siddique MH, Riaz M et al (2018) Bacterial lipases: a review on purification and characterization. Prog Biophys Mol Biol 132:23–34. https://doi.org/10.1016/j.pbiomolbio.2017.07.014
Jiang X, Zou X, Chao Z, Xu X (2022) Preparation of human milk fat substitutes: a review. Life 12:187–193. https://doi.org/10.3390/life12020187
Jose C, Toledo MV, Nicolas P, Lasalle V, Ferreira ML, Briand LE (2018) Influence of the nature of the support on the catalytic performance of CALB: experimental and theoretical evidence. Catal Sci Technol 8:3513–3526 https://doi.org/10.1039/C7CY02466E
Joshi R, Sharma R, Kuila A (2019) Lipase production from Fusarium incarnatum KU377454 and its immobilization using Fe3O4 NPs for application in waste cooking oil degradation. Bioresour Technol Rep 5:134–140. https://doi.org/10.1016/j.biteb.2019.01.005
Kalantzi S, Kekos D, Mamma D (2019) Bioscouring of cotton fabrics by multienzyme combinations: application of Box–Behnken design and desirability function. Cellulose 26:2771–2790 https://link.springer.com/article/10.1007/s10570-019-02272-9
Kasana RC, Pandey CB (2018) Exiguobacterium: an overview of a versatile genus with potential in industry and agriculture. Crit Rev Biotechnol 38:141–156. https://doi.org/10.1080/07388551.2017.1312273
Kebabci O, Cihangir N (2022) A novel yeast isolated from olive mill waste Candida tropicalis; Optimization of medium composition for lipase production. J Fungus 13:8–14.
Khalaf AT, Wei Y, Alneamah SJA, Al-Shawi SG, Kadir SYA, Zainol J, Liu X (2021) What is new in the preventive and therapeutic role of dairy products as nutraceuticals and functional foods? BioMed Res Int 2021:8823222. https://doi.org/10.1155/2021/8823222
Khalid N, Kobayashi I, Neves M, Uemura K, Nakajima M (2018) Microchannel emulsification: a promising technique towards encapsulation of functional compounds. Crit Rev Food Sci Nutr 58:2364–2385. https://doi.org/10.1080/10408398.2017.1323724
Khan J, Deb PK, Priya S, Medina KD, Devi R, Walode SG, Rudrapal M (2021) Dietary flavonoids: cardioprotective potential with antioxidant effects and their pharmacokinetic, toxicological and therapeutic concerns. Molecules 26:4021. https://doi.org/10.3390/molecules26134021
Khanniri E, Bagheripoor N, Sohrabvandi S, Mortazavian M, Khosravi K, Mohammad R (2016) Application of liposomes in some dairy products. Crit Rev Food Sci Nutr 56:484–493. https://doi.org/10.1080/10408398.2013.779571
Kharat M, Skrzynski M, Decker E, McClements D (2020) Enhancement of chemical stability of curcumin-enriched oil-in-water emulsions: impact of antioxidant type and concentration. Food Chem 320:126653. https://doi.org/10.1016/j.foodchem.2020.126653
Kim BH, Akoh CC (2015) Recent research trends on the enzymatic synthesis of structured lipids. J Food Sci 80:C1713–C1724. https://doi.org/10.1111/1750-3841.12953
Kim BH, Hwang J, Akoh CC (2023) Liquid microbial lipase-recent application and expanded use through immobilization. Curr Opin Food Sci 50:100987. https://doi.org/10.1016/j.cofs.2023.100987
Klaunig J (2018) Oxidative stress and cancer. Curr Pharm Des 24:4771–4778. https://doi.org/10.2174/1381612825666190215121712
Knob A, Izidoro SC, Lacerda LT, Rodrigues A, de Lima VA (2020) A novel lipolytic yeast Meyerozyma guilliermondii: efficient and low-cost production of acid and promising feed lipase using cheese whey. Biocatal Agric Biotechnol 24:101565. https://doi.org/10.1016/j.bcab.2020.101565
Kuang G, Wang Z, Luo X, Geng Z, Cui J, Bilal M, Wang Z, Jia S (2023) Immobilization of lipase on hydrophobic MOF synthesized simultaneously with oleic acid and application in hydrolysis of natural oils for improving unsaturated fatty acid production. Int J Biol Macromol 242:124807. https://doi.org/10.1016/j.ijbiomac.2023.124807
Kuepethkaew S, Sangkharak K, Benjakul S, Klomklao S (2017) Laundry detergent-stable lipase from Pacific white shrimp (Litopenaeus vannamei) hepatopancreas: effect of extraction media and biochemical characterization. Int J food Prop 20:769–781. https://doi.org/10.1080/10942912.2016.1180534
Kumar A, Sharma P, Kanwar SS (2012) Lipase catalyzed esters syntheses in organic media: a review. Int J Inst Pharm Life Sci 2:91–119
Kumar A, Verma V, Dubey VK, Strivastava A et al (2023) Industrial application of fungal lipases: a review. Front Microbiol 14:1142536. https://doi.org/10.3389/fmicb.2023.1142536
Kumar JA, Kumar MS (2019) A study on improving dyeability of polyester fabric using lipase enzyme. Autex Res J 20:243–249. https://doi.org/10.2478/aut-2019-0030
Kumari A, Mihooliya KN, Sahoo DK, Bhattacharyya MS et al (2023) Description of lipase producing novel yeast species Debaryomyces apis f.a., sp. nov. and a modifed pH indicator dye-based method for the screening of lipase producing microorganisms. Sci Rep 13:11819. https://doi.org/10.1038/s41598-023-38241-3
Lakshmi LB, Audipudi AV (2021) Biochemical Characterization of Extracellular Lipase from an Improved Strain of Penicillium Citrinum KU613360. Ann Rom Soc Cell Biol 25:7758–7770 https://www.annalsofrscb.ro/index.php/journal/article/view/6965
Lankage UM, Holt SA, Bridge S, Cornell B, Cranfield CG (2023) Triglyceride-tethered membrane lipase sensor. Appl Material Interfaces 15:52237–52243
Leal L, Beltrán J, Marc B, Bello J, den Hartog L, Hendriks W, Martín J (2020) Supplementation of lamb diets with vitamin E and rosemary extracts on meat quality parameters. J Sci Food Agric 100:2922–2931. https://doi.org/10.1002/jsfa.10319
Lee G, Han S (2018) The role of vitamin E in immunity. Nutrients 10:1614. https://doi.org/10.3390/nu10111614
Lee JD, Cai Q, Shu XO, Nechuta SJ (2017) The role of biomarkers of oxidative stress in breast cancer risk and prognosis: a systematic review of the epidemiologic literature. J Women’s Health 26:467–482. https://doi.org/10.1089/jwh.2016.5973
Lesny JE, Mohan AP, Vijaya JA (2022) Bioremediation of petroleum-polluted soil using biosurfactant producing bacteria, Pseudomonas sp. J Sci Res 66:1
Li GL, Fang XR, Su F, Chen Y, Xu L, Yan YJ (2018) Enhancing the thermostability of Rhizomucor miehei lipase with a limited screening library by rational-design point mutations and disulfide bonds. Appl Environ Microbiol 84:e02129–e02117. https://doi.org/10.1128/aem.02129-17
Li HM, Xu TT, Peng QX, Chen YS, Zhou H, Lu YY, Yan RA (2021) Enzymatic acylation of rutin with benzoic acid ester and lipophilic, antiradical, and antiproliferative properties of the acylated derivatives. J Food Sci 86:1714–1725. https://doi.org/10.1111/1750-3841.15703
Li X, Zhao Y, Lai X, Nong J, Zhao G, Xiao X (2020) One-pot biocatalytic synthesis and antioxidant activities of highly lipophilic naringin derivatives by using bi-functional whole-cells. Food Res Int 136:109291. https://doi.org/10.1016/j.foodres.2020.109291
Lien G, Bram P, Karolien D, Jan D (2014) Lipases and their functionality in the production of wheat-based food systems. Compr Rev Food Sci Food Saf 13:978–989. https://doi.org/10.1111/1541-4337.12085
Lien RG, Bram P, Hanne GM, Jan AD (2015) A lipase based approach to understand the role of wheat endogenous lipids in bread crumb firmness evolution during storage. LWT-Food Sci Technol 64:874–880. https://doi.org/10.1016/j.lwt.2015.06.055
Lima LGR, Gonçalves MMM, Couri S, Melo VF, Sant’Ana GCF, Costa ACAD (2019) Lipase production by Aspergillus niger C by submerged fermentation. Braz Arch Biol Technol:62. https://doi.org/10.1590/1678-4324-2019180113
Lira RKDS, Zardini RT, de Carvalho MCC, Wojcieszak R, Leite SGF, Itabaiana I (2021) Agroindustrial wastes as a support for the immobilization of lipase from Thermomyces lanuginosus: synthesis of hexyl laurate. Biomolecules 11:445. https://doi.org/10.3390/biom11030445
Liu W, Li M, Yan Y (2017) Heterologous expression and characterization of a new lipase from Pseudomonas fluorescens Pf0–1 and used for biodiesel production. Sci Rep 7:15711. https://doi.org/10.1038/s41598-017-16036-7
Llerena-Suster CR, Briand LE, Morcelle SR (2014) Analytical characterization and purification of a commercial extract of enzyme: a case study. Colloids Surf B Biointerface 1:11–20. https://doi.org/10.1016/j.colsurfb.2014.05.029
Ma X, Kexin Z, Yonggang W, Ebadi AG, Toughani M (2021) Optimization of low-temperature lipase production conditions and study on enzymatic properties of Aspergillus Niger. Iran J Chem Eng 40:1364–1374. https://doi.org/10.30492/ijcce.2021.529010.4694
Maharana AK, Singh SM (2018) A cold and organic solvent tolerant lipase produced by Antarctic strain Rhodotorula sp. Y-23. J Basic Microbiol 58:331–342
Mahfoudhi A, Benmabrouk S, Fendri A, Sayari A (2022) Fungal lipases as biocatalysts: a promising platform in several industrial biotechnology applications. Biotechnol Bioeng 119:3370–3392. https://doi.org/10.1002/bit.28245
Manoel EA, dos Santos JCS, Freire DMG, Rueda N, Fernandez-Lafuente R (2015) Immobilization of lipases on hydrophobic supports involves the open form of the enzyme. Enzym Microb Technol 71:53–57. https://doi.org/10.1016/j.enzmictec.2015.02.001
Marquez-Villa JM, Mateos-Diaz JC, Rodriguez JA et al (2023) Lipase B from Candida antarctica in highly salin AOT-water- isooctane reverse micelle system for enhanced esterification and reaction. Catalysts 13:492. https://doi.org/10.3390/catal13030492
Martinelli A, Giannini L, Branduardi P (2021) Enzymatic modification of cellulose to unlock its exploitation in advanced materials. ChemBioChem 22:974–981. https://doi.org/10.1002/cbic.202000643
Mateos PS, Casella M, Briand LE, Matkovic SR (2023) Transesterification of waste cooking oil with a commercial liquid biocatalyst: key information and new insights. American Oil Chem Soc 100:278–301. https://doi.org/10.1002/aocs.12683
McKelvey SM, Murphy RA (2017) Biotechnological use of fungal enzymes. Fungi Biol Appl pp:201–225 https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119374312.ch8
Mehta A, Bodh U, Gupta R (2017) Fungal lipases: a review. J Biotech Res 8:58
Melis S, Delcour J (2020) Impact of wheat endogenous lipids on the quality of fresh bread: key terms, concepts, and underlying mechanisms. Compr Rev Food Sci Food Saf 19:3715–3754. https://doi.org/10.1111/1541-4337.12616
Mène-Saffrané L, Pellaud S (2017) Current strategies for vitamin E biofortification of crops. Curr Opin Biotechnol 44:189–197. https://doi.org/10.1016/j.copbio.2017.01.007
Min B, Salt L, Wilde P, Kosik O, Hassall K, Przewieslik A, Burridge A, Poole M, Snape J, Wingen L et al (2020) Genetic variation in wheat grain quality is associated with differences in the galactolipid content of flour and the gas bubble properties of dough liquor. Food Chem 6:100093. https://doi.org/10.1016/j.fochx.2020.100093
Moon Y-S, Ali S (2022) Isolation and identification of multi-trait plant growth–promoting rhizobacteria from coastal sand dune plant species of Pohang beach. Folia Microbiol 67:523–533. https://doi.org/10.1007/s12223-022-00959-4
Mota D, Rajan D, Heinzl G, Osório N, Gominho J, Krause L, Soares C, Nampoothiri M, Sukumaran R, Ferreira S (2020) Production of low-calorie structured lipids from spent coffee grounds or olive pomace crude oils catalyzed by immobilized lipase in magnetic nanoparticles. Bioresour Technol 307:123223. https://doi.org/10.1016/j.biortech.2020.123223
Muralidhar RV, Chirumamilla RR, Ramachandran VN, Marchant R, Nigam P (2001) Racemic resolution of RS-baclofen using lipase from Candida cylindracea. Meded Fak Land Bouwkun Digeen Toegep Biol Wet 66:227–232
Nagarajan S, Nagarajan R, Kumar J, Salemme A, Togna A, Saso L, Bruno F (2020) Antioxidant activity of synthetic polymers of phenolic compounds. Polymers 12:1646. https://doi.org/10.3390/polym12081646
Narayanan N, Chou CP (2009) Alleviation of proteolytic sensitivity to enhance recombinant lipase production in Escherichia coli. Appl Environ Microbiol 75:5424–5427. https://doi.org/10.1128/AEM.00740-09
Neta NS, Teixeira JA, Rodrigues LR (2015) Sugar ester surfactants: enzymatic synthesis and applications in food industry. Crit Rev Food Sci Nutr 55:595–610. https://doi.org/10.1080/10408398.2012.667461
Niyonzima FN, More SS (2015) Microbial detergent compatible lipases. J Sci Ind Res 74:105–113
Njus D, Kelley P, Tu Y, Schlegel H (2020) Ascorbic acid: the chemistry underlying its antioxidant properties. Free Radic Biol Med 159:37–43. https://doi.org/10.1016/j.freeradbiomed.2020.07.013
Ortiz C, Ferreira ML, Barbosa O, dos Santos JC et al (2019) Novozym 435: the perfect lipase immobilized biocatalysts. Catal Sci Technol 175:1–127. https://doi.org/10.1039/C9CY00415G
Oteng A, Kersten S (2020) Mechanisms of action of trans fatty acids. Adv Nutr 11:697–708. https://doi.org/10.1093/advances/nmz125
Ou J, Yuan X, Liu Y, Zhang P, Xu W, Tang K (2021) Lipase from pseudomonas cepacia immobilized into ZIF-8 as bio-catalyst for enantioselective hydrolysis and transesterification. Process Biochem 102:132–140. https://doi.org/10.1016/j.procbio.2020.12.017
Pandey N, Dhakar K, Jain R, Pandey A (2016) Temperature dependent lipase production from cold and pH tolerant species of Penicillium. Mycosphere 7:1533–1545. https://doi.org/10.5943/mycosphere/si/3b/5
Pang Y, Zhang Y, Chen M, Lu W, Chen M, Yan Y, Lin M, Zhang W, Zhou Z (2021) Pseudomonas nanhaiensis sp. nov., a lipase-producing bacterium isolated from deep-sea sediment of the South China Sea. Antonie Van Leeuwenhoek 114:1791. https://doi.org/10.1007/s10482-021-01639-y
Pasha MK, Dai L, Liu D, Du W, Guo M (2021) Biodiesel production with enzymatic technology: progress and perspectives. Biofuel Bioprod Biorefin 15:1526–1548. https://doi.org/10.1002/bbb.2236
Patel GB, Shah KR (2020) Isolation, screening and identification of Lipase producing fungi from cotton seed soapstock. Indian J Sci Technol 13:3762–3771. https://doi.org/10.17485/IJST/v13i36.1099
Patel N, Rai D, Shahane S, Mishra U (2019) Lipases: sources, production, purification, and applications. Recent Pat Biotechnol 13:45–56. https://doi.org/10.2174/1872208312666181029093333
Pathak VM (2017) Review on the current status of polymer degradation: a microbial approach. Bioresour Bioprocess 4:1–31. https://doi.org/10.1186/s40643-017-0145-9
Peng B, Chen F, Liu X, Hu J-N, Zheng L-F, Li J, Deng Z-Y (2020) Trace water activity could improve the formation of 1, 3-oleic-2-medium chain-rich triacylglycerols by promoting acyl migration in the lipase RM IM catalyzed interesterification. Food Chem 313:126130. https://doi.org/10.1016/j.foodchem.2019.126130
Pérez MM, Gonçalves ECS, Vici AC, Salgado JCS, de Moraes PMDLT (2019) In: Yadav AN, Mishra S, Singh S, Gupta A (eds) Fungal lipases: versatile tools for white biotechnology, in recent advancement in white biotechnology through fungi: volume 1: diversity and enzymes perspectives, pp 361–404. https://doi.org/10.1007/978-3-030-10480-1_11
Phukon LC, Chourasia R, Kumari M, Godan TK, Sahoo D, Parameswaran B, Rai AK (2020) Production and characterisation of lipase for application in detergent industry from a novel Pseudomonas helmanticensis HS6. Bioresour Technol 309:123352. https://doi.org/10.1016/j.biortech.2020.123352
Pohanka M (2019) Biosensors and bioassays based on lipases, principles and applications, a review. Molecules 24:616. https://doi.org/10.3390/molecules24030616
Qiu J, Han R, Wang C (2021) Microbial halophilic lipases: a review. J Basic Microbiol 61:594–602. https://doi.org/10.1002/jobm.202100107
Rahimi H, Soro S, Rughetti A, Palocci C, Biffoni M, Barachini S, Taurino F, Cernia E, Frati L, Nuti M (2004) Monoclonal antibodies against Candida rugosa lipase. J Mol Catal B Enzym 28:71–74
Rahman IA, Rahman RN, Salleh AB, Basri M (2013) Formulation and evaluation of an automatic dishwashing detergent containing T1 lipase. J Surfactants Deterg 16:427–434. https://doi.org/10.1007/s11743-012-1398-0
Rahman MBA, Azaman RN, Omar EM, Latif MAM, Abdulmalek E (2019) Candida rugosa lipase immobilized on diethylaminoethyl-cellulose (deae) for esterification of butyl oleate. Malays J Anal Sci 23:376–382. https://doi.org/10.17576/mjas-2019-2303-01
Ramarathinam S, Latha K, Rajalakshmi N (2002) Use of a fungal lipase for enhancement of aroma in black tea. Food Sci Technol Res 8:328–332. https://doi.org/10.3136/fstr.8.328
Rashmi H, Negi P (2020) Phenolic acids from vegetables: a review on processing stability and health benefits. Food Res Int 136:109298. https://doi.org/10.1016/j.foodres.2020.109298
Reyes-Reyes AL, Barranco FV, Sandoval G (2022) Recent advances in lipases and their application in the food and nutraceutical industry. Catalysts 12:960. https://doi.org/10.3390/catal12090960
Richter JL, Zawadzki SF, Alves dos Santos L, Alnoch RC, Moure VR, Mitchell DA, Krieger N (2023) Immobilization of the metagenomic lipase, LipG9, on porous pellets of poly-hydroxybutyrate produced by the double emulsion solvent evaporation technique. Biotechnol Appl Biochem 70:1279–1290. https://doi.org/10.1002/bab.2438
Rios NS, Pinheiro BB, Pinheiro MP, Bezerra RM, dos Santos JCS, Gonçalves LRB (2018) Biotechnological potential of lipases from Pseudomonas: sources, properties and applications. Process Biochem 75:99–120. https://doi.org/10.1016/j.procbio.2018.09.003
Rocha KS, Queiroz MS, Gomes BS, Dallago R, de Souza RO, Guimarães DO et al (2020) Lipases of endophytic fungi Stemphylium lycopersici and Sordaria sp.: application in the synthesis of solketal derived monoacylglycerols. Enzyme Microb Technol 142:109664. https://doi.org/10.1016/j.enzmictec.2020.109664
Rodríguez-Salarichs J, Garcia de Lacoba M, Prieto A, Martínez MJ, Barriuso J (2021) Versatile lipases from the Candida rugosa-like family: a mechanistic insight using computational approaches. J Chem Inf Model 61:913–920 10.1021%2Facs.jcim.0c01151
Rozi MFAM, RNZRA R, ATC L, MSM A (2022) Ancestral sequence reconstruction of ancient lipase from family I. 3 bacterial lipolytic enzymes. Mol Phylogenet Evol 168:107381. https://doi.org/10.1016/j.ympev.2021.107381
Sachdeva V, Roy A, Bharadvaja N (2020) Current prospects of nutraceuticals: a review. Curr Pharm Biotechnol 21:884–896. https://doi.org/10.2174/1389201021666200130113441
Safdar A, Ismail F, Imran M (2023) Characterization of detergent-compatible lipase from Candida albicans and Acremonium sclerotigenum under solid-state fermentation. ACS Omega 8:32740–32751. https://doi.org/10.1021/acsomega.3c03644
Saha SK, Lee SB, Won J, Choi HY, Kim K, Yang GM, Dayem AA, Cho SG (2017) Correlation between oxidative stress, nutrition, and cancer initiation. Int J Mol Sci 18:1544. https://doi.org/10.3390/ijms18071544
Sahoo RK, Kumari KS, Sahoo S, Das A, Gaur M, Dey S, Mohanty S, Subudhi E (2021) Bio-statistical optimization of lipase production by thermophilic Pseudomonas formosensis and its application on oral biofilm degradation. Biocatal Agric Biotechnol 33:101969. https://doi.org/10.1016/j.bcab.2021.101969
Salgado CA, dos Santos CI, Vanetti MCD (2020) Microbial lipases: propitious, biocatalysts for the food industries. Food Biosci 45:101509
Sandoval G, Casas-Godoy L, Bonet-Ragel K, Rodrigues J, Ferreira-Dias S, Valero F (2017) Enzyme-catalyzed production of biodiesel as alternative to chemical-catalyzed processes: advantages and constraints. Curr Biochem Eng 4:109–141. https://doi.org/10.2174/2212711904666170615123640
Sandoval G, Quintana P, Baldessari A, Ballesteros A, Plou F (2015) Lipase-catalyzed preparation of mono- and diesters of ferulic acid. Biocatal Biotransformation 33:89–97. https://doi.org/10.3109/10242422.2015.1060228
Sankaran R, Show PL, Chang JS (2016) Biodiesel production using immobilized lipase: feasibility and challenges. Biofuel Bioprod Biorefin 10:896–916. https://doi.org/10.1002/bbb.1719
Saraswat R, Verma V, Sistla S, Bhushan I (2017) Evaluation of alkali and thermotolerant lipase from an indigenous isolated Bacillus strain for detergent formulation. Electron J Biotechnol 30:33–38. https://doi.org/10.1016/j.ejbt.2017.08.007
Sarmah N, Revathi D, Sheelu G, Yamuna Rani K, Sridhar S, Mehtab V, Sumana C (2018) Recent advances on sources and industrial applications of lipases. Biotechnol Prog 34:5–28. https://doi.org/10.1002/btpr.2581
Saxena RK, Sheoran A, Giri B, Davidson WS (2003) Purification strategies for microbial lipases. J Microbiol Methods 52:1–18. https://doi.org/10.1016/s0167-7012(02)00161-6
Selvam K, Vishnupriya B, Maanvizhi M (2013) Enzymatic synthesis of fragrance ester by lipase from marine Actinomycetes for textile industry. Int J Eng Adv Technol 3:91–96
Shabbir AROOSH, Mukhtar H (2018) Optimization process for enhanced extracellular lipases production from a new isolate of Aspergillus terreus ah-F2. Pak J Bot 50:1571–1578
Shalini P, Deepanraj B, Vijayalakshmi S, Ranjitha J (2021) Synthesis and characterisation of lipase immobilised magnetic nanoparticles and its role as a catalyst in biodiesel production. Mater Today Proc 80:2725–2730. https://doi.org/10.1016/j.matpr.2021.07.027
Shao S, Shi Y, Wu Y, Bian L, Zhu Y, Huang X, Pan Y, Zeng L, Zhang R (2018) Lipase-catalyzed synthesis of sucrose monolaurate and its antibacterial property and mode of action against four pathogenic bacteria. Molecules 23:1118. https://doi.org/10.3390/molecules23051118
Sharma S, Bose JC (2023) Lipase-producing bacteria as probiotics and recent advancement. Popul Therap Clin Pharmacol 30:453–470
Sharma S, Kanwar SS (2014) Organic solvent tolerant lipases and applications. Sci World J 2014:625258. https://doi.org/10.1155/2014/625258
Sharma SH, Kanwar K, Kanwar SHS (2016) Ascorbyl palmitate synthesis in an organic solvent system using a celite-immoblized commercial lipase. 3Biotech 6:183. https://doi.org/10.1007/s13205-016-0486-7
Shehata M, Ünlü A, Iglesias-Fernández J, Osuna S, Sezerman OU, Timucin E (2023) Brave new surfactant world revisited by thermoalkalophilic lipases: computational insights into the role of SDS as a substrate analog. Phys Chem Phys 25:2234–2247. https://doi.org/10.1039/D2CP05093E
Shi Y, Bian L, Zhu Y, Zhang R, Shao S, Wu Y, Chen Y, Dang Y, Ding Y, Sun H (2019) Multifunctional alkyl ferulate esters as potential food additives: antibacterial activity and mode of action against Listeria monocytogenes and its application on American sturgeon caviar preservation. Food Control 96:390–402. https://doi.org/10.1016/j.foodcont.2018.09.030
Shi Y, Wu Y, Lu X, Ren Y, Wang Q, Zhu C, Yu D, Wang H (2017) Lipase-catalyzed esterification of ferulic acid with lauryl alcohol in ionic liquids and antibacterial properties in vitro against three food-related bacteria. Food Chem 220:249–256. https://doi.org/10.1016/j.foodchem.2016.09.187
Shojaei M, Golmakani M, Eskandari M, Toh M, Liu S (2021) Natural flavor biosynthesis by lipase in fermented milk using in situ produced ethanol. J Food Sci Technol 58:1858–1868
Show PL, Tan CP, Anuar MS, Ariff A, Yusof YA, Chen SK, Ling TC (2011) Direct recovery of lipase derived from Burkholderia cepacia in recycling aqueous two-phase flotation. Sep Purif Technol 80:577–584
Sies H, Jones D (2020) Reactive oxygen species (ROS) as pleiotropic physiological signaling agents. Nat Reviews Mol Cell Biol 21:363–383. https://doi.org/10.1038/s41580-020-0230-3
Singh AK, Mukhopadhyay M (2012) Overview of fungal lipase: a review. Appl Biochem Biotechnol 166:486–520. https://doi.org/10.1007/s12010-011-9444-3
Singh N, Verma A, Kaur I, Chattopadhyay S (2022) A comprehensive review on the potential use of immobilized lipase as biosensor-present scenario and prospect. Res J Biotechnol 17:145–150. https://doi.org/10.25303/1704rjbt145150
Soares V, Marini M, de Paula L, Gabry P, Amaral A, Malafaia C, Leal I (2021) Umbelliferone esters with antibacterial activity produced by lipase-mediated biocatalytic pathway. Biotechnol Lett 43:469–477. https://doi.org/10.1007/s10529-020-03014-9
Sokač Cvetnić T, Šalić A, Benković M, Jurina T, Valinger D, Gajdoš Kljusurić J, Zelić B, Jurinjak Tušek A (2023) A Systematic review of enzymatic kinetics in microreactors. Catalysts 13:708. https://doi.org/10.3390/catal13040708
Soni S (2022) Trends in lipase engineering for enhanced biocatalysis. Biotechnol Appl Biochem 69:265–272. https://doi.org/10.1002/bab.2105
Souza RL, Lima RA, Coutinho JAP, Soares CMF, Lima ÁS (2015) Novel aqueous two-phase systems based on tetrahydrofuran and potassium phosphate buffer for purification of lipase. Process Biochem 50:1459–1467
Subroto E, Nurhasanah S, Munarso SJ (2021) Lipase immobilization by adsorption technique on the hydrophobically modified matrix. Int J Eng Trends Technol 69:49–55. https://doi.org/10.14445/22315381/IJETT-V69I1P208
Sun L, Xin F, Alper H (2021) Bio-synthesis of food additives and colorants-a growing trend in future food. Biotechnol Adv 47:107694. https://doi.org/10.1016/j.biotechadv.2020.107694
Swat M, Rybicka I, Gliszczynska A (2019) Characterization of fulvic acid beverages by mineral profile and antioxidant capacity. Foods 8:605. https://doi.org/10.3390/foods8120605
Tan B, Norhaizan M, Liew W (2018) Nutrients and oxidative stress: friend or foe? Oxidative Med Cell Longev 2018:9719584. https://doi.org/10.1155/2018/9719584
Tan CH, Show PL, Ooi CW, Ng EP, Lan JCW, Ling TC (2015) Novel lipase purification methods—a review of the latest developments. Biotechnol J 10:31–44. https://doi.org/10.1002/biot.201400301
Tanini D, Lupori B, Malevolti G, Ambrosi M, Nostro P, Capperucci A (2019) Direct biocatalysed synthesis of first sulfur-, selenium and tellurium-containing l-ascorbyl hybrid derivatives with radical trapping and GPx-like properties. Chem Commun 55:5705–5708. https://doi.org/10.1039/C9CC02427A
Tecelão C, Perrier V, Dubreucq E, Ferreira S (2019) Production of human milk fat substitutes by interesterification of tripalmitin with ethyl oleate catalyzed by Candida parapsilosis lipase/acyltransferase. J Am Oil Chem Soc 96:777–787. https://doi.org/10.1002/aocs.12250
Temkov M, Muresan V (2021) Tailoring the structure of lipids, oleogels and fat replacers by different approaches for solving the trans-fat issue—a review. Foods 10:1376. https://doi.org/10.3390/foods10061376
Thabet HS, Seddik I, Mohamed WA et al (2023) Isolation, screening and molecular identification of lipase-producing bacteria from different bacterial sources. Assiut Vet Med J 69:134–144. https://doi.org/10.21608/avmj.2023.213953.1147
Thangaraj B, Solomon PR (2019) Immobilization of lipases—a review. Part I: enzyme immobilization. ChemBioEng Rev 6:157–166. https://doi.org/10.1002/cben.201900016
Thirunavukarasu K, Purushothaman S, Sridevi J, Aarthy M, Gowthaman MK, Nakajima-Kambe T et al (2016) Degradation of poly (butylene succinate) and poly (butylene succinate-co-butylene adipate) by a lipase from yeast Cryptococcus sp. grown on agro-industrial residues. Int Biodeterior Biodegrad 110:99–107. https://doi.org/10.1016/j.ibiod.2016.03.005
Tian M, Yang L, Lv P, Wang Z, Fu J, Miao C, Li Z, Li L, Liu T, Du W (2022) Improvement of methanol tolerance and catalytic activity of Rhizomucor miehei lipase for one-step synthesis of biodiesel by semi-rational design. Bioresour Technol 348:126769. https://doi.org/10.1016/j.biortech.2022.126769
Tišma M, Tadic T, BudŽaki S, Ostojčić M, Šalić A, Zelić B et al (2019) Lipase ´ production by solid-state cultivation of Thermomyces lanuginosus on by-products from cold-pressing oil production. Processes 7:465. https://doi.org/10.3390/pr7070465
Toldrá-Reig F, Mora L, Toldrá F (2020) Developments in the use of lipase transesterification for biodiesel production from animal fat waste. Appl Sci 10:5085. https://doi.org/10.3390/app10155085
Toledo MV, Briand LE (2017) Relevance and bio-catalytic strategies for the kinetic resolution of ketoprofen towards dexketoprofen. Crit Rev Biotechnol 38:778–800. https://doi.org/10.1080/07388551.2017.1399249
Toledo MV, Briand LE, Ferreiro ML (2022) A simple molecular model to study the substrate diffusion into the active site of a lipase-catalyzed esterification of ibuprofen and ketoprofen with glycerol. Topics Catal 65:944–956. https://doi.org/10.1007/s11244-022-01636-z
Toledo MV, Jose C, Collins SE, Ferreira ML, Briand LE (2015) Towards a green enantiomeric esterification of R/S-ketoprofen: a theoretical and experimental investigation. J Mol Catal B Enz 118:52–61. https://doi.org/10.1016/j.molcatb.2015.05.003
Toledo MV, Suster CR, Ferreira ML, Collins SE, Briand LE (2017) Molecular recognition of an acyl-enzyme intermediate on the lipase B from Candida antarctica. Catal Sci Technol 7:1953–1964. https://doi.org/10.1039/C7CY00245A
Toledo MV, Suster L, Rafael CR et al (2019) Influence of water on enzymatic esterification of racemic ketoprofen with ethanol in a solvent-free system. Topics Catal 62:968–976 https://link.springer.com/article/10.1007/s11244-019-01184-z
Tomasz P, Maciej B (2021) The study on the use of flavonoid- prhosphatidylcholilne coating in extending the oxidative stability of flaxseed oil during storage. Food Packag Sheld Life 28:5. https://doi.org/10.1016/j.fpsl.2021.100643
Torres P, Plou F, Ballesteros A (2012) Modificación de antioxidantes fenólicos mediante procesos enzimáticos. In: Plou FJ, Sandoval G (eds) Obtención Enzimática de Compuestos Bioactivos a Partir de Recursos Naturales Iberoamericanos. CSIC, Madrid, Spain, pp 151–163
Torres P, Reyes-Duarte D et al (2008) Acetylation of vitamin E by Candida antarctica lipase B immobilized on different carrier. Process Biochem 43:145–153. https://doi.org/10.1016/j.procbio.2007.11.008
Trifkovi´c K, Benkovi´c M (2019) Chapter 1-Introduction to nutraceuticals and pharmaceuticals. In: Galanakis CM (ed) In Nutraceuticals and natural product pharmaceuticals. Academic Press, Cambridge, MA, USA, pp 1–31
Tufiño C, Bernal C, Ottone C, Romero O, Illanes A, Wilson L (2019) Synthesis with immobilized lipases and downstream processing of ascorbyl palmitate. Molecules 24:3227. https://doi.org/10.3390/molecules24183227
Vanleeuw E, Winderickx S, Thevissen K, Lagrain B, Dusselier M, Cammue BPA, Sels BF (2019) Substrate-specificity of Candida Rugosa lipase and its industrial application. ACS Sustainable Chem Eng 7:15828–15844. https://doi.org/10.1021/acssuschemeng.9b03257
Wang HT, Ding J, Xiong C, Zhu D, Li G, Jia XY, Zhu YG, Xue XM (2019a) Exposure to microplastics lowers arsenic accumulation and alters gut bacterial communities of earthworm Metaphire californica. Environ Pollut 251:110–116. https://doi.org/10.1016/j.envpol.2019.04.054
Wang R, Wang S, Xu Y, Yu X (2020) Enhancing the thermostability of Rhizopus chinensis lipase by rational design and MD simulations. Int J Biol Macromol 160:1189–1200. https://doi.org/10.1016/j.ijbiomac.2020.05.243
Wang W, Li J, Zhang H, Wang X, Fan J, Zhang X (2019b) Phenolic compounds and bioactivity evaluation of aqueous and methanol extracts of Allium mongolicum regel. Food Sci Nutr 7:779–787. https://doi.org/10.1002/fsn3.926
Wang Y, Ma R, Li S, Gong M, Yao B, Bai Y et al (2018) An alkaline and surfactant-tolerant lipase from Trichoderma lentiforme ACCC30425 with high application potential in the detergent industry. AMB Express 8:1–11. https://doi.org/10.1186/s13568-018-0618-z
Wei CH, Fu XF, Wang ZH, Yu X (2014) Efficient synthesis of vitamin E intermediate by lipase-catalyzed regioselective transesterification. J Mol Catal B 106:23–38. https://doi.org/10.1016/j.molcatb.2014.05.003
Wei W, Jin Q, Wang X (2019) Human milk fat substitutes: past achievements and current trends. Prog Lipid Res 74:69–86. https://doi.org/10.1016/j.plipres.2019.02.001
Welz P, Swanepoel G, Weels S, Le Roes-Hill M (2021) Wastewater from the edible oil industry as a potential source of lipase-and surfactant-producing actinobacteria. Microorganisms 9:1987. https://doi.org/10.3390/microorganisms9091987
Wenfei T, Gengjun C, Michael T, Yonghui L (2021) Changes in phenolic profiles and antioxidant activities during the whole wheat bread-making process. Food Chem 345:128851. https://doi.org/10.1016/j.foodchem.2020.128851
Wu D, Nie X, Shen D, Li H, Zhao L, Zhang Q, Lin D, Qin W (2020) Phenolic compounds, antioxidant activities, and inhibitory effects on digestive enzymes of different cultivars of okra (Abelmoschus esculentus). Molecules 25:1276. https://doi.org/10.3390/molecules25061276
Xia J, Zou B, Zhou R, Onyinye AI (2020) Lipase nanogel catalyzed synthesis of vitamin E succinate in non-aqueous phase. J Sci Food Agric 101:3186–3192. https://doi.org/10.1002/jsfa.10947
Xu L, Yang T, Wang J, Huang F, Zheng M (2021b) Immobilized lipase based on hollow mesoporous silicon spheres for efficient enzymatic synthesis of resveratrol ester derivatives. J Agric Food Chem 69:9067–9075. https://doi.org/10.1021/acs.jafc.0c07501
Xu L, Yu J, Wang A, Zuo CH, Li H, Chen X et al (2018) Efficient synthesis of vitamin A palmitate in nonaqueous medium using self-assmbled lipase TLL@apatite hybrid nanoflowers by mimetic biomineralization. Green Chem Lett 11:476–483. https://doi.org/10.1080/17518253.2018.1536227
Xu Z, Cen YK, Zou SP, Xue YP, Zheng YG (2020) Recent advances in the improvement of enzyme thermostability by structure modification. Crit Rev Biotechnol 40:83–98. https://doi.org/10.1080/07388551.2019.1682963
Yadav M, Kavadia M, Vadgama R, Odaneth A, Lali A (2018) Production of 6-O-l-ascorbyl palmitate by immobilized Candida antarctica Lipase B. Appl Biochem Biotechnol 184:1168–1186. https://doi.org/10.1007/s12010-017-2610-5
Yan J, Yan Y, Madzak C, Han B (2017) Harnessing biodiesel-producing microbes: from genetic engineering of lipase to metabolic engineering of fatty acid biosynthetic pathway. Crit Rev Biotechnol 37:26–36. https://doi.org/10.3109/07388551.2015.1104531
Yang C, Luo P, Zeng Z, Wang H, Malafa M, Suh N (2020) Vitamin E and cancer prevention: studies with different forms of tocopherols and tocotrienols. Mol Carcinog 59:365–389. https://doi.org/10.1002/mc.23160
Yang W, Kortesniemi M, Yang B, Zheng J (2021) Enzymatic acylation of anthocyanins isolated from alpine bearberry (Arctostaphylos alpina) and lipophilic properties, thermostability, and antioxidant capacity of the derivatives. J Agric Food Chem 66:2909–2916. https://doi.org/10.1021/acs.jafc.7b05924
Yao C, Yuan A, Zhang H, Li B, Liu J, Xi F, Dong X (2019) Facile surface modification of textiles with photocatalytic carbon nitride nanosheets and the excellent performance for self-cleaning and degradation of gaseous formaldehyde. J. Colloid Interface Sci 533:144–153. https://doi.org/10.1016/j.jcis.2018.08.058
Yao CH, Lin W, Yue K, Ling XP (2017) Biocatalytic synthesis of vitamin A palmitate using immobilized lipase produced by recombinant Pichia pastoris. Eng Life Sci 17:1–20. https://doi.org/10.1002/elsc.201600178
Yasar G, Gulhan UG, Guduk E, Aktas F (2020) Screening, partial purification and characterization of the hyper-thermophilic lipase produced by a new isolate of Bacillus subtilis LP2. Biocatal Biotransform 38:367–375
Yasin MT, Ali Y, Ahmad K, Ghani A, Amanat K, Basheir MM, Faheem M, Hussain S, Ahmad B, Hussain A (2021) Alkaline lipase production by novel meso-tolerant psychrophilic Exiguobacterium sp. strain (AMBL-20) isolated from glacier of northeastern Pakistan. Arch Microbiol 203:1309–1320. https://doi.org/10.1007/s00203-020-02133-1
Yaver DS, Lamsa M, Munds R, Brown SH, Otani S, Franssen L et al (2000) Using DNA-tagged mutagenesis to improve heterologous protein production in Aspergillus oryzae. Fungal Genet Biol 29:28–37. https://doi.org/10.1006/fgbi.1999.1179
Yin CH, Liu T, Tan T (2006) Synthesis of vitamin A esters by immobilized Candida sp. lipase in organic media. Chem Eng 14:81–86. https://doi.org/10.1016/S1004-9541(06)60041-4
Yu XW, Wang R, Zhang M, Xu Y, Xiao R (2012) Enhanced thermostability of a Rhizopus chinensis lipase by in vivo recombination in Pichia pastoris. Microb Cell Factories 11:1–11
Yu Z, Yu H, Xu J, Wang Z, Wang Z, Kang T, Chen K, Pu Z, Wu J, Yang L (2022) Enhancing thermostability of lipase from Pseudomonas alcaligenes for producing l-menthol by the CREATE strategy. Catal Sci Technol 12:2531–2541. https://doi.org/10.1039/D2CY00082B
Zeb A (2020) Concept, mechanism, and applications of phenolic antioxidants in foods. J Food Biochem 44:e13394. https://doi.org/10.1111/jfbc.13394
Zehani N, Kherrat R, Jaffrezic-Renault N (2014) Immobilization of Candida Rugosa lipase on aluminosilicate incorporated in a polymeric membrane for the elaboration of an impedimetric biosensor. Sens Transducers 27:371
Zhang HY, Wang X, Ching CB, Wu JC (2005) Experimental optimization of enzymic kinetic resolution of racemic flurbiprofen. Biotechnol Appl Biochem 42:67–71. https://doi.org/10.1042/ba20040163
Zhang Q, Cheng Z, Wang Y, Fu L (2021) Dietary protein-phenolic interactions: characterization, biochemical-physiological consequences, and potential food applications. Crit Rev Food Sci Nutr 61:3589–3615. https://doi.org/10.1080/10408398.2020.1803199
Zhang S, Riccardi C, Kamen D, Reilly J, Mattila J, Bak H, Xiao H, Li N (2022a) Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases. Pharm Res 39:75–87. https://doi.org/10.1007/s11095-021-03160-3
Zhang T, Zhang Y, Deng CH, Zhang H, Gu T et al (2022b) Green and efficient synthesis of highly liposoluble and antioxidant L-ascorbyl esters by immobilized lipases. Clean Production 379:134772. https://doi.org/10.1016/j.jclepro.2022.134772
Zhang Z, Zhang S, Lee WJ, Lai OM, Tan CP, Wang Y (2020) Production of structured triacylglycerol via enzymatic interesterification of medium-chain triacylglycerol and soybean oil using a pilot-scale solvent-free packed bed reactor. J Am Oil Chem Soc 97:271–280. https://doi.org/10.1080/14756366.2020.1861607
Zhao J, Ma M, Zeng Z, Yu P, Gong D, Deng S (2021) Production, purification and biochemical characterisation of a novel lipase from a newly identified lipolytic bacterium Staphylococcus caprae NCU S6. J Enzym Inhib Med Chem 36:249–257. https://doi.org/10.1080/14756366.2020.1861607
Zhao W, Wang J, Deng R, Wang X (2008) Scale-up fermentation of recombinant Candida rugosa lipase expressed in Pichia pastoris using the GAP promoter. J Ind Microbiol 35:189–195. https://doi.org/10.1007/s10295-007-0283-8
Zhou P, Shao R, Wang H, Miao J, Wang X (2020) Dietary vitamin A, C, and E intake and subsequent fracture risk at various sites: a meta-analysis of prospective cohort studies. Medicine 99:e20841
Zhou Q, Jiao L, Qiao Y, Wang Y, Xu L, Yan J et al (2019) Overexpression of GRAS Rhizomucor miehei lipase in Yarrowia lipolytica via optimizing promoter, gene dosage and fermentation parameters. J Biotechnol 306:16–23. https://doi.org/10.1016/j.jbiotec.2019.09.004
Zieniuk B, Białecka E, Wierzchowska K, Fabiszewska A (2021b) Recent advances in the enzymatic synthesis of lipophilic antioxidant and antimicrobial compounds. World J Microbiol Biotechnol 38:11
Zieniuk B, Groborz K, Wołoszynowska M, Ratusz K, Białecka E, Fabiszewska A (2021) Enzymatic synthesis of lipophilic esters of phenolic compounds, evaluation of their antioxidant activity and effect on the oxidative stability of selected oils. Biomolecules 11:314. https://doi.org/10.3390/biom11020314
Zieniuk B, Wołoszynowska M, Białecka E, Fabiszewska A (2021a) Application of freeze-dried Yarrowia lipolytica biomass in the synthesis of lipophilic antioxidants. Biotechnol. Lett 43:601–612. https://doi.org/10.1007/s10529-020-03033-6
Zou Z, Dai L, Liu D, Du W (2021) Research progress in enzymatic synthesis of vitamin E ester derivatives. Catalysts 11:739. https://doi.org/10.3390/catal11060739
Zulkeflee SA, Rohman FS, Sata SA, Aziz N (2022) Temperature and water activity control in a lipase catalyzed esterification process using nonlinear model predictive control. Can J Chem Eng 100:3669–3690. https://doi.org/10.1002/cjce.24358
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The authors would like to thank the members of the Enzyme and Microbial Technology Research Center (EMTech) for the constructive comments and help in the completion of this manuscript.
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This project was supported by the Prototype Research Grant Scheme (PRGS) from the Ministry of Higher Education (MoHE) Malaysia PRGS/1/2021/STG02/UPM/02/2 which was awarded to the last author (SNO).
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Eskandari, A., Leow, T.C., Rahman, M.B.A. et al. Recent insight into the advances and prospects of microbial lipases and their potential applications in industry. Int Microbiol (2024). https://doi.org/10.1007/s10123-024-00498-7
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DOI: https://doi.org/10.1007/s10123-024-00498-7