Abstract
A novel electrochemical sensor based on nickel-doped cobalt ferrite nanoparticles (Ni0.1Co0.9Fe2O4)-modified glassy carbon electrode (NCF/GCE) was presented for the sensitive detection of paracetamol. Experimental conditions such as pH, applied potentials and concentration were investigated using cyclic voltammetric and chronoamperometric techniques. The modified electrode exhibited excellent catalytic response towards the oxidation of paracetamol with good reproducibility. The overpotential for oxidation of paracetamol is decreased, and the current response enhanced significantly on the modified electrode in comparison with that of bare electrode. Linear calibration curve is obtained over the range 2 μM to 8,000 μM having a detection limit of 11 nM. The modified electrode facilitated the simultaneous detection of paracetamol, ascorbic acid, and dopamine with good reproducibility.
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Acknowledgement
The authors would like to thank the financial support from the University Grants Commission, New Delhi and Sophisticated Test and Instrumentation center Cochin, Indian Institute of Technology Madars and Bombay for providing their instrumental facilities.
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Vidyadharan, A.K., Jayan, D. & Mary Nancy, T.E. Ni0.1Co0.9Fe2O4-based electrochemical sensor for the detection of paracetamol. J Solid State Electrochem 18, 2513–2519 (2014). https://doi.org/10.1007/s10008-014-2476-1
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DOI: https://doi.org/10.1007/s10008-014-2476-1