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Automatic sequential injection analysis electronic tongue with integrated reference electrode for the determination of ascorbic acid, uric acid and paracetamol

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Abstract.

A new approach towards a voltammetric electronic tongue has been developed. Automation of the system was achieved by the use of a sequential injection analysis (SIA) system. Design and construction of a small detection device containing 3 working electrodes was carried out. Platinum, gold and epoxy-graphite discs were used for this purpose. An Ag/AgCl reference electrode was integrated into the measuring cell in order to minimise electrical noise. Three oxidisable compounds of clinical interest i.e., ascorbic acid, uric acid and paracetamol, could be quantified by the system. Employing the voltammograms as departure information, artificial neural networks (ANN) have been used as chemometric tool for the modelling of the system.

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References

  • Y Vlasov A V Legin (1998) ArticleTitleNon-selective chemical sensors in analytical chemistry: from “electronic nose” to “electronic tongue” Fresenius J Anal Chem 361 255 Occurrence Handle10.1007/s002160050875 Occurrence Handle1:CAS:528:DyaK1cXjvFCntLs%3D

    Article  CAS  Google Scholar 

  • Y Vlasov A V Legin A M Rudnistkaya A D’Amico C Di Natale (2000) ArticleTitle“Electronic tongue” – new analytical tool for liquid analysis on the basis of non-specific sensors and methods of pattern recognition Sens Actuators B 65 235 Occurrence Handle10.1016/S0925-4005(99)00323-8

    Article  Google Scholar 

  • K Toko (1998) ArticleTitleA taste sensor Meas Sci Technol 9 1919 Occurrence Handle10.1088/0957-0233/9/12/001 Occurrence Handle1:CAS:528:DyaK1cXnvF2isrs%3D

    Article  CAS  Google Scholar 

  • P Ivarsson M Johansson N-E Höjer C Krantz-Rülcker F Winquist I Lundström (2005) ArticleTitleSupervision of rinses in a washing machine by a voltammetric electronic tongue Sens Actuators B 108 851 Occurrence Handle10.1016/j.snb.2004.12.088

    Article  Google Scholar 

  • C Krantz-Rülcker M Stenberg F Winquist I Lundström (2001) ArticleTitleElectronic tongues for environmental monitoring based on sensor arrays and pattern recognition: a review Anal Chim Acta 426 217 Occurrence Handle10.1016/S0003-2670(00)00873-4

    Article  Google Scholar 

  • H Men S Zou Y Li Y Wang X Ye P Wang (2005) ArticleTitleA novel electronic tongue combined MLAPS with stripping voltammetry for environmental detection Sens Actuators B 110 350 Occurrence Handle10.1016/j.snb.2005.02.032

    Article  Google Scholar 

  • C Di Natale A Macagnano F Davide A D’Amico A Legin Y Vlasov A Rudnitskaya B Selezenev (1997) ArticleTitleMulticomponent analysis on polluted waters by means of an electronic tongue Sens Actuators B 44 423 Occurrence Handle10.1016/S0925-4005(97)00169-X

    Article  Google Scholar 

  • R Martinez-Máñez J Soto E Garcia-Breijo L Gil J Ibáñez E Llobet (2005) ArticleTitleAn “electronic tongue” design for the qualitative analysis of natural waters Sens Actuators B 104 302 Occurrence Handle10.1016/j.snb.2004.05.022

    Article  Google Scholar 

  • A Legin A Rudnitskaya B Seleznev Y Vlasov (2005) ArticleTitleElectronic tongue for quality assessment of ethanol, vodka and eau-de-vie Anal Chim Acta 534 129 Occurrence Handle10.1016/j.aca.2004.11.027 Occurrence Handle1:CAS:528:DC%2BD2MXis1ChsLY%3D

    Article  CAS  Google Scholar 

  • F Winquist R Bjorklund C Krantz-Rülcker I Lundström K Östergren T Skoglund (2005) ArticleTitleAn electronic tongue in the dairy industry Sens Actuators B 111–112 299 Occurrence Handle10.1016/j.snb.2005.05.003

    Article  Google Scholar 

  • C Söderström H Borén F Winquist C Krantz-Rülcker (2003) ArticleTitleUse of an electronic tongue to analyze mold growth in liquid media Intern J Food Microbiol 83 253 Occurrence Handle10.1016/S0168-1605(02)00375-6

    Article  Google Scholar 

  • P Ivarsson S Holmin N-E Höjer C Krantz-Rülcker F Winquist (2001) ArticleTitleDiscrimination of tea by means of a voltammetric electronic tongue and different applied waveforms Sens Actuators B 76 449 Occurrence Handle10.1016/S0925-4005(01)00583-4

    Article  Google Scholar 

  • J Gallardo S Alegret R Muñoz M de-Román L Leija P R Hernández M del Valle (2003) ArticleTitleAn electronic tongue using potentiometric all-solid-state PVC-membrane sensors for the simultaneous quantification of ammonium and potassium ions in water Anal Bioanal Chem 377 248 Occurrence Handle10.1007/s00216-003-2042-7 Occurrence Handle1:CAS:528:DC%2BD3sXmvVKgsL0%3D

    Article  CAS  Google Scholar 

  • F Winquist E Rydberg S Holmin C Krantz-Rülcker I Lundström (2002) ArticleTitleFlow injection analysis applied to a voltammetric electronic tongue Anal Chim Acta 471 159 Occurrence Handle10.1016/S0003-2670(02)00923-6 Occurrence Handle1:CAS:528:DC%2BD38XotVyrurk%3D

    Article  CAS  Google Scholar 

  • A Gutés F Céspedes M del Valle D Louthander C Krantz-Rülcker F Winquist (2006) ArticleTitleA flow injection voltammetric electronic tongue applied to paper mill industrial waters Sens Actuators B 115 390 Occurrence Handle10.1016/j.snb.2005.09.024

    Article  Google Scholar 

  • A Gutés F Céspedes S Alegret M del Valle (2005) ArticleTitleSequential Injection system with higher dimensional electrochemical sensor signals. Part 1: voltammetric e-tongue for the determination of oxidisable compounds Talanta 66 1187 Occurrence Handle10.1016/j.talanta.2005.01.022

    Article  Google Scholar 

  • M Cortina A Gutés S Alegret M del Valle (2005) ArticleTitleSequential Injection system with higher dimensional electrochemical sensor signals. Part 2: potentiometric e-tongue for the determination of alkaline ions Talanta 66 1197 Occurrence Handle10.1016/j.talanta.2005.01.023 Occurrence Handle1:CAS:528:DC%2BD2MXltFGlu78%3D

    Article  CAS  Google Scholar 

  • X Llopis A Merkoçi M del Valle S Alegret (2005) ArticleTitleIntegration of a glucose biosensor based on an epoxy-graphite-TTFTCNQ-GOD biocomposite into a FIA system Sens Actuators B 107 742 Occurrence Handle10.1016/j.snb.2004.12.006

    Article  Google Scholar 

  • A Gutés A B Ibáñez M del Valle F Céspedes (2006) ArticleTitleAutomated SIA e-tongue employing a biosensor array for the simultaneous determination of glucose and ascorbic acid Electroanalysis 18 IssueID1 82 Occurrence Handle10.1002/elan.200503378

    Article  Google Scholar 

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Correspondence to Manuel del Valle.

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Gutés, A., Calvo, D., Céspedes, F. et al. Automatic sequential injection analysis electronic tongue with integrated reference electrode for the determination of ascorbic acid, uric acid and paracetamol. Microchim Acta 157, 1–6 (2007). https://doi.org/10.1007/s00604-006-0660-4

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  • DOI: https://doi.org/10.1007/s00604-006-0660-4

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