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A novel electrochemical sensor based on magneto LDH/Fe3O4 nanoparticles @ glassy carbon electrode for voltammetric determination of tramadol in real samples

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Abstract

The electrochemical behavior of tramadol (TRA) on magneto layer double hydroxide (LDH)/Fe3O4@glassy carbon electrode (LDH/Fe3O4@GCE) was evaluated. Some theoretical thermodynamic and kinetic parameters were also determined using chronoamperometric and voltammetric methods. The ability of the modified electrode to determine trace amounts of TRA was studied using differential pulse voltammetry (DPV) as a sensitive electrochemical method. For characterizing and investigating the performance of LDH/Fe3O4@GCE, various methods including scanning electron microscopy (SEM), X-ray diffraction (XRD), cyclic voltammetry (CV), and DPV were used. The effect of pH, scan rate, and time on the voltammetric response of TRA were investigated. Under the optimized conditions, the anodic peak current was linear for the concentration of TRA in the range 1.0–200.0 μmol L−1 with the detection limit of 3.0 × 10−1 μmol L−1. This method was also successfully used to detect the concentration of TRA in human serum and urine samples.

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Acknowledgments

The authors acknowledge Bu-Ali Sina University and Urmia University Research Council and Center of Excellence in Development of Environmentally Friendly Methods for Chemical Synthesis (CEDEFMCS) for providing support to this work.

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Authors and Affiliations

  1. Faculty of Chemistry, Bu-Ali Sina University, Hamadan, 65178638695, Iran

    Tayyebeh Madrakian, Sakineh Alizadeh & Abbas Afkhami

  2. Department of Chemistry, Faculty of Science, Urmia University, Urmia, 5715175976, Iran

    Morteza Bahram

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  1. Tayyebeh Madrakian
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  2. Sakineh Alizadeh
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  3. Morteza Bahram
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  4. Abbas Afkhami
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Correspondence to Tayyebeh Madrakian.

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Madrakian, T., Alizadeh, S., Bahram, M. et al. A novel electrochemical sensor based on magneto LDH/Fe3O4 nanoparticles @ glassy carbon electrode for voltammetric determination of tramadol in real samples. Ionics 23, 1005–1015 (2017). https://doi.org/10.1007/s11581-016-1871-2

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  • DOI: https://doi.org/10.1007/s11581-016-1871-2

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