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A concise stereoselective total synthesis of diplodialide C

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Abstract

An asymmetric total synthesis of diplodialide C has been achieved starting from commercially available homoallylic alcohol. Regioselective opening of the chiral epoxide, cross-metathesis reaction, and Yamaguchi macrolactonization were used as the key steps in this synthesis.

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Acknowledgments

We are grateful to CSIR-IICT, Hyderabad for providing analytical facilities.

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Authors and Affiliations

  1. Department of Chemistry, Krishna University, Machilipatnam, 521 001, Andhra Pradesh, India

    Bommareddy Pratapareddy & Mandava Venkata Basaveswara Rao

  2. Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur, 522510, Andhra Pradesh, India

    Reddymasu Sreenivasulu, Islavathu Hatti & Rudraraju Ramesh Raju

Authors
  1. Bommareddy Pratapareddy
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  2. Reddymasu Sreenivasulu
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  3. Islavathu Hatti
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  4. Mandava Venkata Basaveswara Rao
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  5. Rudraraju Ramesh Raju
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Corresponding authors

Correspondence to Mandava Venkata Basaveswara Rao or Rudraraju Ramesh Raju.

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Pratapareddy, B., Sreenivasulu, R., Hatti, I. et al. A concise stereoselective total synthesis of diplodialide C. Monatsh Chem 146, 1921–1926 (2015). https://doi.org/10.1007/s00706-015-1464-1

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  • DOI: https://doi.org/10.1007/s00706-015-1464-1

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