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Ultrathin PdCu alloy nanosheet–assembled 3D nanoflowers with high peroxidase-like activity toward colorimetric glucose detection

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Abstract

Enzyme-mimetic properties of nanomaterials can be efficiently tuned by controlling their size, composition, and structure. Here, ultrathin PdCu alloy nanosheet–assembled three-dimensional (3D) nanoflowers (Pd1Cux NAFs) with tunable surface composition are obtained via a generalized strategy. In presence of H2O2, the as-synthesized Pd1Cux NAFs can catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to the oxidized form of TMB (oxTMB) with a characteristic absorption peak at 652 nm. Interestingly, Pd1Cux NAFs show obviously composition-dependent peroxidase-like catalytic activities because of the synergistic interaction of nanoalloy. Additionally, different from 2D Pd nanosheets, the distinctive 3D superstructures are featured with rich approachable sites and proper layer spacing, which are in favor of fast mass transport and electron transfers during the catalytic process. Among the studied Pd1Cux NAFs, the Pd1Cu1.7 NAFs show the highest enzyme-like activities and can be successfully applied for the colorimetric detection of glucose with a low detection limit of 2.93 ± 0.53 μM. This work provides an efficient avenue to fabricate PdCu NAF nanozymes in biosensing toward glucose detection.

Graphical abstract

Two-dimensional (2D) PdCu ultrathin nanosheet–assembled 3D nanoflowers (Pd1Cux NAFs) with tunable surface composition exhibit substantially enhanced intrinsic peroxidase-like catalytic activities. The Pd1Cu1.7 NAFs are successfully used as peroxidase mimic catalyst for the colorimetric detection of glucose with low detection limit of 2.93 μM.

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Funding

This work was supported by the National Natural Science Foundation of China (21904048, 21902062 and 21902061), the Young Taishan Scholars Program (tsqn201812080), and the Natural Science Foundation of Shandong Province (ZR2019YQ10 and ZR2020QB033).

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Authors and Affiliations

  1. School of Materials Science and Engineering, University of Jinan, Jinan, 250022, China

    Wendong Liu, Junnan Guo, Chuanxia Chen, Pengjuan Ni, Yuanyuan Jiang, Chenghui Zhang, Bo Wang & Yizhong Lu

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  1. Wendong Liu
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  2. Junnan Guo
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  3. Chuanxia Chen
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  4. Pengjuan Ni
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  5. Yuanyuan Jiang
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Correspondence to Yuanyuan Jiang, Chenghui Zhang or Yizhong Lu.

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Liu, W., Guo, J., Chen, C. et al. Ultrathin PdCu alloy nanosheet–assembled 3D nanoflowers with high peroxidase-like activity toward colorimetric glucose detection. Microchim Acta 188, 114 (2021). https://doi.org/10.1007/s00604-021-04776-3

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