Abstract
Glutathione, a non-protein thiol molecule is present in abundance in the human body. It plays a major role in maintaining the intracellular redox states, metabolism and detoxification. A novel idea is introduced where zinc oxide nanoparticles are used for the fluorescence sensing of Glutathione. Zinc oxide nanoparticles prepared by the co-precipitation method has been annealed at 400 °C, 700 °C and 900 °C. XRD studies confirmed the evolution of phase and hexagonal wurtzite structure. FESEM images confirm the high degree of crystallinity. Optical absorption measurements exhibit a red shift in absorption for unannealed, 400 °C and 700 °C and a decrease in absorption wavelength for particle annealed at 900 °C. In addition, the bandgap energy decreases with an increase in annealing temperature indicating the increase in particle size. Photoluminescence studies in room temperature at an excitation of 330 nm show emission in the UV and visible regions. Quenching of fluorescence emission intensity due to electron transfer is noticed while increasing the concentration of Glutathione in nanomolar(nM) range. Quenching of PL intensity due to adsorption-induced electron transfer is explained through band bending effect. These results indicate that zinc oxide nanoparticles can be implemented for optoelectronics, solar photocatalysts and glutathione sensing applications.
Similar content being viewed by others
References
S. Das, S. Mukhopadhyay, S. Chatterjee, P.S. Devi, G. Suresh Kumar, ACS Omega 3, 7494 (2018)
X. Zhang, Z. Guo, X. Zhang, L. Gong, X. Dong, Y. Fu, Q. Wang, Z. Gu, Sci. Rep. 9, 1 (2019)
F.W. Pratiwi, C.W. Kuo, B.C. Chen, P. Chen, Nanomedicine 14, 1759 (2019)
W. Chen, C.A. Glackin, M.A. Horwitz, J.I. Zink, Acc. Chem. Res. 52, 1531 (2019)
X. Ma, S. He, B. Qiu, F. Luo, L. Guo, Z. Lin, ACS Sens. 4, 782 (2019)
M. Pastucha, Z. Farka, K. Lacina, Z. Mikušová, P. Skládal, Microchim. Acta 186, 312 (2019)
D. Liu, B. Li, G. Li, L. Wang, X. Yang, Mater. Lett. 196, 37 (2017)
E. Muchuweni, T.S. Sathiaraj, H. Nyakotyo, Heliyon 3, e00285 (2017)
N. Gogurla, S.C. Kundu, S.K. Ray, Nanotechnology 28, 145202 (2017)
A. Raja, S. Ashokkumar, R. Pavithra Marthandam, J. Jayachandiran, C.P. Khatiwada, K. Kaviyarasu, R. Ganapathi Raman, M. Swaminathan, J. Photochem. Photobiol. B Biol. 181, 53 (2018)
W. Li, Y.J. Guo, Q.B. Tang, X.T. Zu, J.Y. Ma, L. Wang, K. Tao, H. Torun, Y.Q. Fu, Surf. Coat. Technol. 363, 419 (2019)
X. Zeng, W. Liu, L. Zhang, Z. Wang, S. Li, F. Zhang, T. Wang, Y. Liao, Proceedings of 2019 5th International Conference on Electric Power Equipment—Switching Technology Front. Switch. Technol. a Futur. Sustain. Power Syst. ICEPE-ST 2019 339 (2019).
B. Sun, X. Li, R. Zhao, H. Ji, J. Qiu, N. Zhang, D. He, C. Wang, J. Mater. Sci. 54, 2754 (2019)
K. Kaviyarasu, G.T. Mola, S.O. Oseni, K. Kanimozhi, C.M. Magdalane, J. Kennedy, M. Maaza, J. Mater. Sci. Mater. Electron. 30, 147 (2019)
G.D. Patil, A.H. Patil, S.A. Jadhav, C.R. Patil, P.S. Patil, Mater. Lett. 255, 126562 (2019)
A. Bhogale, N. Patel, J. Mariam, P.M. Dongre, A. Miotello, D.C. Kothari, A.I.P. Conf, Proc. 1512, 130 (2013)
J.I. Hahm, J. Nanosci. Nanotechnol. 14, 475 (2014)
K. Aoyama, T. Nakaki, Molecules 20, 8742 (2015)
Q. Jin, Y. Li, J. Huo, X. Zhao, Sens. Actuators B Chem. 227, 108 (2016)
P. Ni, D. Jiang, C. Chen, Y. Jiang, Y. Lu, Z. Zhao, Analyst 143, 4442 (2018)
L.Y. Niu, M.Y. Jia, P.Z. Chen, Y.Z. Chen, Y. Zhang, L.Z. Wu, C.F. Duan, C.H. Tung, Y.F. Guan, L. Feng, Q.Z. Yang, RSC Adv. 5, 13042 (2015)
L. Li, Q. Wang, Z. Chen, Microchim. Acta 186, 0 (2019).
X. Sun, P. Heinrich, R.S. Berger, P.J. Oefner, K. Dettmer, Anal. Chim. Acta 1080, 127 (2019)
M. Hanko, Ľ. Švorc, A. Planková, P. Mikuš, Anal. Chim. Acta 1062, 1 (2019)
A.A. Ensafi, T. Khayamian, F. Hasanpour, J. Pharm. Biomed. Anal. 48, 140 (2008)
Z. Abolghasemi-Fakhri, M. Amjadi, J.L. Manzoori, Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 216, 85 (2019)
Z. Amouzegar, A. Afkhami, T. Madrakian, Microchim. Acta 186, (2019).
P. Hou, J. Sun, H. Wang, L. Liu, L. Zou, S. Chen, Sens. Actuators B Chem. 304, 127244 (2020)
W. Dong, R. Wang, X. Gong, C. Dong, Anal. Bioanal. Chem. 411, 6687 (2019)
P. Nedeljko, M. Turel, A. Lobnik, J. Sensors 2018, (2018).
H.B. Wang, Y. Chen, Y. Li, Y.M. Liu, RSC Adv. 6, 79526 (2016)
J. Ungula, B.F. Dejene, H.C. Swart, Results Phys. 7, 2022 (2017)
D. Raoufi, J. Lumin. 134, 213 (2013)
S.S. Kumar, P. Venkateswarlu, V.R. Rao, G.N. Rao, Int Nano Lett 3, 301 (2014)
T. Dippong, O. Cadar, E.A. Levei, I.G. Deac, G. Borodi, Ceram. Int. 44, 10478 (2018)
T. Dippong, E.A. Levei, O. Cadar, F. Goga, D. Toloman, G. Borodi, J. Therm. Anal. Calorim. 136, 1587 (2019)
T. Dippong, E.A. Levei, O. Cadar, I.G. Deac, L. Diamandescu, L. Barbu-Tudoran, J. Alloys Compd. 786, 330 (2019)
A. Khorsand Zak, W.H. Abd. Majid, M.E. Abrishami, R. Yousefi, Solid State Sci. 13, 251 (2011)
V. Mote, Y. Purushotham, B. Dole, J. Theor. Appl. Phys. 6, 2 (2012)
P. Triloki, R. Rai Garg, B.K. Singh, Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip. 736, 128 (2014)
N. Chaithanatkun, K. Onlaor, B. Tunhoo, Key Eng. Mater. 728, 215 (2017)
D. Verma, A.K. Kole, P. Kumbhakar, J. Alloys Compd. 625, 122 (2015)
T. Dippong, D. Toloman, E.A. Levei, O. Cadar, A. Mesaros, Thermochim. Acta 666, 103 (2018)
M. Ghosh, A.K. Raychaudhuri, Nanotechnology 19, 445704 (2008)
N. Goswami, D.K. Sharma, Phys. E Low-Dimension. Syst. Nanostruct. 42, 1675 (2010)
L. Irimpan, V.P.N. Nampoori, P. Radhakrishnan, A. Deepthy, B. Krishnan, J. Appl. Phys. 102, 063524 (2007)
V. Kumar, H.C. Swart, O.M. Ntwaeaborwa, R.E. Kroon, J.J. Terblans, S.K.K. Shaat, A. Yousif, M.M. Duvenhage, Mater. Lett. 101, 57 (2013)
R. Joseph, Z. Lakowic, Principles of Fluorescence Spectroscopy, 3rd edn. (Springer, US, 2006)
Z. Zhang, J.T. Yates, J. Phys. Chem. Lett. 1, 2185 (2010)
Z. Zhang, J.T. Yates, Chem. Rev. 112, 5520 (2012)
Y. Qiu, J. Huang, L. Jia, Int. J. Anal. Chem. 2018, 1979684 (2018)
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Kannan, J., Balasubramanian, K. Thermally influenced, optical and fluorescence properties of Zinc Oxide nanoparticles for glutathione sensing. Appl. Phys. A 126, 602 (2020). https://doi.org/10.1007/s00339-020-03780-3
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s00339-020-03780-3