Abstract
Air is a complex amalgamation of gases, water vapor, and dust particles. With development in civilized human society and later on boom in industrialization, there is drastic change in the air quality levels. Levels of different gaseous pollutants, heavy metals, particulate matter, volatile organic compounds, and other pollutants are constantly rising up in the air majorly due to combustion of solid fuels and fossil fuels. All these pollutants greatly diverge in their chemical composition, reaction time and mechanism of action. Depending on the exposure time and concentration, these pollutants can exert various toxicological impacts on human health such as respiratory, neurological, and cardiovascular disorder and other life-threatening diseases like cancer. Air pollution has also been connected with premature child birth, morbidity, mortality and reduced life expectancy. In this chapter, the sources of air pollution their effects on different organs and systems in human body as well as their mechanism of action will be discussed.
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References
Abhyankar LN, Jones MR, Guallar E, Navas-Acien A (2012) Arsenic exposure and hypertension: a systematic review. Environ Health Perspect 120:494–500
Addiss DG, Shaffer N, Fowler BS, Tauxe RV (1990) The epidemiology of appendicitis and appendectomy in the United States incidental appendectomies are commonly performed at the time of other abdominal or pelvic surgery to prevent future appendicitis (16). Because the epidemiology of incidental ap. Am J Epidemiol 132:910–925
Aksu A (2015) Sources of metal pollution in the urban atmosphere (A case study: Tuzla, Istabul). J Environ Health Sci Eng 13:79. https://doi.org/10.1186/s40201-015-0224-9
Alissa EM, Ferns GA (2011) Heavy metal poisoning and cardiovascular disease. J Toxicol. https://doi.org/10.1155/2011/870125
Amodio-Cocchieri R (1996) LEAD in human blood from children living in CAMPANIA, ITALY. J Toxicol Environ Health 47(4):311–320
An Z, Jin Y, Li J, Li W, Wu W (2018) Impact of particulate air pollution on cardiovascular health. Curr Allergy Asthma Rep 18(3):15
Ananthakrishnan AN, Mcginley EL, Binion DG (2011) Ambient air pollution correlates with hospitalizations for inflammatory bowel disease: an ecologic analysis. Inflamm Bowel Dis 17:1138–1145. https://doi.org/10.1002/ibd.21455
Apostoli P, Kiss P, Porru S et al (1998) Male reproductive toxicity of lead in animals and humans. Occup Environ Med 55:364–374
Araujo JA (2011) Particulate air pollution, systemic oxidative stress, inflammation, and atherosclerosis. Atmos Health 4:79–93. https://doi.org/10.1007/s11869-010-0101-8
Aris RM, Christian D, Hearne PQ et al (1993) Ozone-induced airway inflammation in human subjects as determined by airway lavage and biopsy. Am J Respir Crit Care Med 148:1363–1372
Asher I, Pearce N (2014) Global burden of asthma among children. Int J Tuberc Lung Dis 18:1269–1278
Asker S, Asker M, Yeltekin AC, Aslan M, Ozbay B, Demir H, Turan H (2018) Serum levels of trace minerals and heavy metals in severe COPD patients with and without pulmonary hypertension. Int J Chron Obstruct Pulmon Dis 13:1803–1808
Ballard C, Gauthier S, Corbett A et al (2011) Alzheimer’ s disease. Lancet 377:1019–1031. https://doi.org/10.1016/S0140-6736(10)61349-9
Baudouin C, Charveron M, Tarroux R et al (2002) Environmental pollutants and skin cancer. Cell Biol Toxicol 18:341–348
Beelen R, Hoek G, Van Den Brandt PA et al (2008) Long-term exposure to traffic-related air pollution and lung cancer risk. Epidemiology 19:702–710. https://doi.org/10.1097/EDE.0b013e318181b3ca
Belanger K, Gent JF, Triche EW et al (2006) Association of indoor nitrogen dioxide exposure with respiratory symptoms in children with asthma. Am J Respir Crit Care Med 173:297–303. https://doi.org/10.1164/rccm.200408-1123OC
Bevan R, Young C, Holmes P et al (2012) Occupational cancer in Britain Gastrointestinal cancers: liver, oesophagus, pancreas and stomach. Br J Cancer 107:S33–S40. https://doi.org/10.1038/bjc.2012.116
Beyer A, Mackay D, Matthies M, Wania F, Webster E (2000) Assessing long-range transport potential of persistent organic pollutants. Environ Sci Technol 4(4):699–703
Beyersmann D, Hartwig A (2008) Carcinogenic metal compounds: recent insight into molecular and cellular mechanisms. Arch Toxicol 82:493–512. https://doi.org/10.1007/s00204-008-0313-y
Block ML, Calderón-Garcidueñas L (2009) Air pollution: mechanisms of neuroinflammation and CNS disease. Trends Neurosci 32:506–516. https://doi.org/10.1016/j.tins.2009.05.009
Block ML, Elder A, Auten RL et al (2012) The outdoor air pollution and brain health workshop. Neurotoxicology 33:972–984. https://doi.org/10.1016/j.neuro.2012.08.014
Bobak M (2000) Outdoor air pollution, low birth weight, and prematurity. Environ Health Perspect 108:173–176
Bogden JD, Gertner SB, Kemp FW et al (1991) Dietary lead and calcium: effects on blood pressure and renal neoplasia in Wistar rats. Minerals Trace Elements 121:718–728
Brook RD (2007) Why physicians who treat hypertension should know more about air pollution. J Clin Hypertens 9:629–635
Broome RA, Fann N, Navin TJ et al (2015) The health benefits of reducing air pollution in Sydney, Australia. Environ Res 143:19–25. https://doi.org/10.1016/j.envres.2015.09.007
Calderón-Garcidueñas L, Solt AC, Carlos Henríquez-Roldán RJ, Bryan Nuse L, Herritt R-C et al (2008) Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid β −42 and α-synuclein in children and young. Toxicol Pathol 36:289–310. https://doi.org/10.1177/0192623307313011
Cao J, Yang C, Li J et al (2011) Association between long-term exposure to outdoor air pollution and mortality in China: a cohort study. J Hazard Mater 186:1594–1600. https://doi.org/10.1016/j.jhazmat.2010.12.036
Carré J, Gatimel N, Moreau J et al (2017) Does air pollution play a role in infertility?: a systematic review. Environ Health 16:82. https://doi.org/10.1186/s12940-017-0291-8
Cesaroni G, Stafoggia M, Galassi C et al (2014) Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE project. BMJ 348:f7412. https://doi.org/10.1136/bmj.f7412
Chen C, Modrek S (2018) Gendered impact of solid fuel use on acute respiratory infections in children in China. BMC Public Health 18(1):1170. https://doi.org/10.1186/s12889-018-6035-z
Chen T, Shofer S, Gokhale J, Kuschner WG (2007) Outdoor air pollution: overview and historical perspective. Med Sci 333:230–234. https://doi.org/10.1097/MAJ.0b013e31803b8c91
Chen G, Wan X, Yang G, Zou X (2014) Traffic-related air pollution and lung cancer: a meta-analysis. Thorac Cancer 6:307–318. https://doi.org/10.1111/1759-7714.12185
Chen JC, Wang X, Wellenius GA, Serre ML, Driscoll I, Casanova R, McArdle JJ, Manson JE, Chui HC, Espeland MA (2015) Ambient air pollution and neurotoxicity on brain structure: evidence from women’s health initiative memory study. Ann Neurol 78:466–476. https://doi.org/10.1002/ana.24460.Ambient
Choi H, Wook D, Kim W et al (2011) Asian dust storm particles induce a broad toxicological transcriptional program in human epidermal keratinocytes. Toxicol Lett 200:92–99. https://doi.org/10.1016/j.toxlet.2010.10.019
Clarkson TW, Magos L, Myers GJ (2003) The toxicology of mercury — current exposures and clinical manifestations. N Engl J Med 349:1731–1737
Colt JS, Friesen MC, Stewart PA et al (2014) A case-control study of occupational exposure to metal working fluids and bladder cancer risk among men. Occup Environ Med 71:667–674. https://doi.org/10.1136/oemed-2014-102362.221.A
Creţu DI, Sovrea A, Ignat RM, Filip A, Bidian C, Creţu AURICA (2010) Morpho-pathological and physiological changes of the brain and liver after ozone exposure. Rom J Morphol Embryol 51:701–706
Das S, Grewal A, Banerjee M (2011) A brief review: heavy metal and their analysis. Int J Pharm Sci Rev Res 11:13–18
Davignon J, Ganz P (2004) Role of endothelial dysfunction in atherosclerosis. Circulation 109:III27. https://doi.org/10.1161/01.CIR.0000131515.03336.f8
Dejmek J, Jelínek R, Solansky I, Benes I, Srám RJ (2000) Fecundability and parental exposure to ambient sulfur dioxide. Environ Health Perspect 108:647–654
Desai HG, Gupte PA (2005) Increasing incidence of Crohn’s disease in India: is it related to improved sanitation? Indian J Gastroenterol 24(1):23
Dhar A, Young MR, Colburn NH (2002) The role of AP-1, NF-κB and ROS/NOS in skin carcinogenesis: the JB6 model is predictive. Mol Cell Biochem 234:185–193
Dockery DW, Pope CA (1994) Acute respiratory effects of particulate air pollution. Annu Rev Public Health 15:107–132
Dockery DW, Pope CA, Xu X et al (1993) An association between air pollution and mortality in six US cities. N Engl J Med 329:1753–1175
Dunnick JK, Elwell MR, Radovsky AE et al (1995) Comparative carcinogenic effects of nickel subsulfide, nickel oxide, or nickel sulfate hexahydrate chronic exposures in the Lung1. Cancer Res 55:5251–5256
Duruibe JO, Ogwuegbu MOC, Egwurugwu JN (2007) Heavy metal pollution and human biotoxic effects. Int J Phys Sci 2:112–118
Dybdahl M, Risom L, Mùller P et al (2003) DNA adduct formation and oxidative stress in colon and liver of Big Blue Ò rats after dietary exposure to diesel particles. Carcinogenesis 24:1759–1766. https://doi.org/10.1093/carcin/bgg147
Fabbrocini G, Triassi M, Mauriello MC et al (2010) Epidemiology of skin cancer: role of some environmental factors. Cancers (Basel) 2:1980–1989. https://doi.org/10.3390/cancers2041980
Faiz AS, Rhoads GG, Demissie K et al (2012) Ambient air pollution and the risk of stillbirth. Am J Epidemiol 176:308–316. https://doi.org/10.1093/aje/kws029
Faustini A, Rapp R, Forastiere F (2014) Nitrogen dioxide and mortality: review and meta-analysis of long-term studies. Eur Respir J 44:744–753. https://doi.org/10.1183/09031936.00114713
Feng Z, Hu W, Rom WN et al (2003) Chromium (VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells Chromium (VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells. Carcinogenesis 24:771–778. https://doi.org/10.1093/carcin/bgg012
Firket BYJ, March RI (1936) Fog along the Meuse valley. Trans Faraday Soc 32:1192–1196
Fortoul TI, Rojas-Lemus M, Rodriguez-Lara V, Cano-Gutierrez G, Gonzalez-Villalva A, Ustarroz-Cano M, … Gonzalez-Rendon ES (2011) Air pollution and its effects in the respiratory system. The Impact of Air Pollution on Health, Economy, Environment and Agricultural Sources 41
Frampton MW, Boscia J, Roberts NJ et al (2002) Nitrogen dioxide exposure: effects on airway and blood cells. Am J Physiol Cell Mol Physiol 2982:L155–L165
Frutos V, González-Comadrá M, Solà I et al (2015) Impact of air pollution on fertility: a systematic review. Gynecol Endocrinol 31(1):7–13. https://doi.org/10.3109/09513590.2014.958992
Gallagher CM, Meliker JR (2010) Blood and urine cadmium, blood pressure, and hypertension: a systematic review and meta-analysis. Environ Health Perspect 118:1676–1684. https://doi.org/10.1289/ehp.1002077
García-pérez J, López-cima MF, Pérez-gómez B, Aragonés N (2010) Science of the total environment mortality due to tumours of the digestive system in towns lying in the vicinity of metal production and processing installations. Sci Total Environ 408:3102–3112. https://doi.org/10.1016/j.scitotenv.2010.03.051
Genc S, Zadeoglulari Z, Fuss SH, Genc K (2012) The adverse effects of air pollution on the nervous system. J Toxicol 2012:782462. https://doi.org/10.1155/2012/782462
Ghio AJ, Kim C, Devlin RB (2000) Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers. Am J Respir Crit Care Med 162:981–988
Ghozikali MG, Mosaferi M, Safari GH, Jaafari J (2015) Effect of exposure to O3, NO2, and SO2 on chronic obstructive pulmonary disease hospitalizations in Tabriz, Iran. Environ Sci Pollut Res 22:2817–2823. https://doi.org/10.1007/s11356-014-3512-5
Green RS, Malig B, Windham GC et al (2009) Residential exposure to traffic and spontaneous abortion. Environ Health Perspect 117:1939–1944. https://doi.org/10.1289/ehp.0900943
Guarnieri M, Balmes JR (2014) Outdoor air pollution and asthma. Lancet 383(9928):1581–1592
Guo Y, Tong S, Li S et al (2010) Gaseous air pollution and emergency hospital visits for hypertension in Beijing, China: a time-stratified case-crossover study. Environ Health 9:57
Guxens M, Sunyer J (2012) A review of epidemiological studies on neuropsychological effects of air pollution. Swiss Med Wkly 141(1):w13322
Halliwell B, Cross CE (1994) Oxygen-derived species: their relation to human disease and environmental stress. Environ Health Perspect 102:5–12
Harlan WR (1988) The relationship of blood lead levels to blood pressure in the U.S. population. Environ Health Perspect 78:9–13
Harlan WR, Landis JR, Schmouder RL et al (1985) Blood lead and blood pressure relationship in the adolescent and adult US population. JAMA 253:530–514
He QC, Tavakkol A, Wietecha K et al (2006) Effects of environmentally realistic levels of ozone on stratum corneum function. Int J Cosmet Sci 28:349–357
Hecht SS (1999) Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91:1194–1210
Heo J, Park HS, Hong Y et al (2017) Serum heavy metals and lung function in a chronic obstructive pulmonary disease cohort. Toxicol Environ Health Sci 9:30–35. https://doi.org/10.1007/s13530-017-0300-x
Hertz-Picciotto I (2000) The evidence that lead increases the risk for spontaneous abortion. Am J Ind Med 38(3):300–309
Hong Y, Lee J, Kim H et al (2002a) Effects of air pollutants on acute stroke mortality. Environ Health Perspect 110:187–191
Hong Y-C, Lee J-T, Kim H, Kwon H-J (2002b) Air Pollution. Stroke 33(9):2165–2169
Houston MC (2011) Role of mercury toxicity in hypertension, cardiovascular disease, and stroke. J Clin Hypertens 13:621–627. https://doi.org/10.1111/j.1751-7176.2011.00489.x
Ibald-mulli A, Stieber J, Koenig W, Peters A (2001) Effects of air pollution on blood pressure: a population-based approach. Am J Public Health 91:571–577
Iskandar A, Andersen ZJ, Bønnelykke K, Ellermann T, Andersen KK, Bisgaard H (2012) Coarse and fine particles but not ultrafine particles in urban air trigger hospital admission for asthma in children. Thorax 67(3):252–257
Jaishankar M, Tseten T, Anbalagan N et al (2014) Toxicity, mechanism and health effects of some heavy metals. Interdiscip Toxicol 7:60–72. https://doi.org/10.2478/intox-2014-0009
Jiang XQ, Mei XD, Feng D (2016) Air pollution and chronic airway diseases: what should people know and do? J Thorac Dis 8:E31–E40
Johns DO, Linn WS (2011) A review of controlled human SO2 exposure studies contributing to the US EPA integrated science assessment for sulfur oxides. Inhal Toxicol 23:33–43. https://doi.org/10.3109/08958378.2010.539290
Kampa M, Castanas E (2008) Human health effects of air pollution. Environ Pollut 151:362–367. https://doi.org/10.1016/j.envpol.2007.06.012
Kaplan GG, Dixon E, Panaccione R, Fong A, Chen L, Szyszkowicz M et al (2009) Effect of ambient air pollution on the incidence of appendicitis. CMAJ 181(9):591–597
Kaplan GG, Hubbard J, Korzenik J et al (2010) The inflammatory bowel diseases and ambient air pollution: a novel association. Am J Gastroenterol 105:2412–2419. https://doi.org/10.1038/ajg.2010.252
Kathuria P, Silverberg JI (2016) Association of pollution and climate with atopic eczema in US children. Pediatr Allergy Immunol 27:478–485. https://doi.org/10.1111/pai.12543
Kaul B, Sandhu RS, Depratt C et al (1999) Follow-up screening of lead-poisoned children near an auto battery recycling plant, Haina, Dominican Republic. Environ Health Perspect 107:917–920
Kawane H, Soejima R, Umeki S, Niki Y (1988) Metal fume fever and asthma. Chest 93:1116–1117. https://doi.org/10.1378/chest.93.5.1116b
Kayamba V, Heimburger DC, Morgan DR et al (2017) Exposure to biomass smoke as a risk factor for oesophageal and gastric cancer in low-income populations: a systematic review. Malawi Med J 29:212–217
Kelfkens G, De Gruijl FR, Van Der Leun JC (1991) Tumorigenesis by short-wave ultraviolet A: papillomas versus squamous cell carcinomas. Carcinogenesis 12:1377–1382
Khaniabadi YO, Daryanoosh M, Sicard P et al (2018) Chronic obstructive pulmonary diseases related to outdoor PM10, O3, SO2, and NO2 in a heavily polluted megacity of Iran. Environ Sci Pollut Res 25:17726–17734
Kim AL, Labasi ÃJM, Zhu Y et al (2005) Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice. J Invest Dermatol 124:1318–1325. https://doi.org/10.1111/j.0022-202X.2005.23747.x
Kim KH, Jahan SA, Kabir E, Brown RJ (2013) A review of airborne polycyclic aromatic hydrocarbons (PAHs) and their human health effects. Environ Int 60:71–80. https://doi.org/10.1016/j.envint.2013.07.019
Kim E, Kim S, Lee JH et al (2015) Indoor air pollution aggravates symptoms of atopic dermatitis in children. PLoS One 10:e0119501. https://doi.org/10.1371/journal.pone.0119501
Kirschvink N, Fi L, Wirth D et al (2005) Repeated cadmium nebulizations induce pulmonary MMP-2 and MMP-9 production and enphysema in rats. Toxicology 211(1–2):36–48. https://doi.org/10.1016/j.tox.2005.02.012
Kirschvink N, Martin N, Fievez L et al (2009) Airway inflammation in cadmium-exposed rats is associated with pulmonary oxidative stress and emphysema. Free Radic Res 40:241–250. https://doi.org/10.1080/10715760500494657
Kobal AB, Horvat M, Preze M et al (2004) The impact of long-term past exposure to elemental mercury on antioxidative capacity and lipid peroxidation in mercury miners. J Trace Elem Med Biol 17:261–274
Kohen R, Gati I (2000) Skin low molecular weight antioxidants and their role in aging and in oxidative stress. Toxicology 148:149–157
Kramer U, Sugiri D, Ranft U, Krutmann J et al (2009) Eczema, respiratory allergies, and traffic-related air pollution in birth cohorts from small-town areas. J Dermatol Sci 56:99–105. https://doi.org/10.1016/j.jdermsci.2009.07.014
Krishnan RM, Adar SD, Szpiro AA, Jorgensen NW, Hee V et al (2012) Vascular responses to long-and short-term exposure to fine particulate matter: MESA Air (Multi-Ethnic Study of Atherosclerosis and Air Pollution). J Am Coll Cardiol 60(21):2158–2166
Krutmann J, Liu W, Li L et al (2014) Pollution and skin: from epidemiological and mechanistic studies to clinical implications. J Dermatol Sci 76:163–168. https://doi.org/10.1016/j.jdermsci.2014.08.008
Kulle TJ, Sauder LR, Hebel JR, Miller WR, Green DJ, Shanty F (1986) Pulmonary effects of sulfur dioxide and respirable carbon aerosol. Environ Res 41:239–250
Kumarathasan P, Vincent R, Blais E et al (2018) Cardiovascular and inflammatory mechanisms in healthy humans exposed to air pollution in the vicinity of a steel mill. Part Fibre Toxicol 15(1):34
Künzli N, Jerrett M, Mack WJ et al (2005) Ambient air pollution and atherosclerosis in Los Angeles. Environ Health Perspect 113:201–206. https://doi.org/10.1289/ehp.7523
Künzli N, Jerrett M, Garcia-Esteban R et al (2010) Ambient air pollution and the progression of atherosclerosis in adults. PLoS One 5(2):e9096. https://doi.org/10.1371/journal.pone.0009096
Kurt OK, Zhang J, Pinkerton KE (2016) Pulmonary health effects of air pollution. Curr Opin Pulm Med 22(2):138
Landolph JR (1994) Molecular mechanisms of transformation of C3H/1OT1/2 Cl 8 mouse embryo cells and diploid human fibroblasts by carcinogenic metal compounds. Environ Health Perspect 102:119–125
Larsen FS (1993) Atopic dermatitis: a genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 28:719–723. https://doi.org/10.1016/0190-9622(93)70099-F
Lee B, Kim B, Lee K (2014) Air pollution exposure and cardiovascular disease. Toxicol Res 30:71–75
Leem AY, Kim SK, Chang J et al (2015) Relationship between blood levels of heavy metals and lung function based on the Korean National Health and nutrition examination survey IV–V. Int J Chron Obstruct Pulmon Dis 10:1559
Legro RS, Sauer MV, Mottla GL et al (2010) Effect of air quality on assisted human. Hum Reprod 25:1317–1324. https://doi.org/10.1093/humrep/deq021
Lelieveld J, Evans JS, Fnais M et al (2015) The contribution of outdoor air pollution sources to premature mortality on a global scale. Nature 525:367–371. https://doi.org/10.1038/nature15371
Leonardi-Bee J, Ellison T, Bath-Hextall F (2012) Smoking and the risk of nonmelanoma skin cancer: systematic review and meta-analysis. Arch Dermatol 148(8):939–946
Levesque S, Taetzsch T et al (2011) Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity. Environ Health Perspect 119:1149–1155. https://doi.org/10.1289/ehp.1002986
Li W, Pan M, Chung M et al (2006) Lead exposure is associated with decreased serum Paraoxonase 1 (PON1) activity and genotypes. Environ Health Perspect 114:1233–1236. https://doi.org/10.1289/ehp.9163
Liu S, Krewski D, Shi Y et al (2003) Association between gaseous ambient air pollutants and adverse pregnancy outcomes in Vancouver, Canada. Environ Health Perspect 111:1773–1778. https://doi.org/10.1289/ehp.6251
Liu SK, Cai S, Chen Y, Xiao B, Chen P, Xiang XD (2016) The effect of pollutional haze on pulmonary function. J Thoracic Dis 8(1):E41–E56
Logan RF (1998) Inflammatory bowel disease incidence: up, down or unchanged? Gut 42:309–311
Lopez IA, Acuna D, Beltran-parrazal L et al (2008) Oxidative stress and the deleterious consequences to the rat cochlea after prenatal chronic mild exposure to carbon monoxide in air. Neuroscience 151:854–867. https://doi.org/10.1016/j.neuroscience.2007.10.053
Lopez-abente G, Garcia-perez J, Boldo E, Ramis R (2012) Colorectal cancer mortality and industrial pollution in Spain. BMC Public Health 12:589. https://doi.org/10.1186/1471-2458-12-589
Lorenz MW, Polak JF, Kavousi M et al (2014) Carotid intima-media thickness progression to predict cardiovascular events in the general population (the PROG-IMT collaborative project): a meta-analysis of individual participant data. Lancet 379:2053–2062. https://doi.org/10.1016/S0140-6736(12)60441-3.Carotid
Lucchini RG, Martin CJ, Doney BC (2009) From manganisum to manganese-induced parkinsonism: a conceptual model based on the evolution of exposure. NeuroMolecular Med 11:311–321. https://doi.org/10.1007/s12017-009-8108-8
Mabahwi NAB, Ling O et al (2014) Human health and wellbeing: human health effect of air pollution. Proce Soc Behav Sci 153:221–229. https://doi.org/10.1016/j.sbspro.2014.10.056
Mahalingaiah S, Hart JE, Laden F et al (2016) Adult air pollution exposure and risk of infertility in the Nurses’ Health Study II. Hum Reprod 31(3):638–647
Maheswaran R, Haining RP, Brindley P et al (2005) Outdoor air pollution and stroke in sheffield, United Kingdom a small-area level geographical study. Stroke 36:239–243. https://doi.org/10.1161/01.STR.0000151363.71221.12
Mancebo SE, Wang SQ (2015) Recognizing the impact of ambient air pollution on skin health. J Eur Acad Dermatol Venereol 29:2326–2332. https://doi.org/10.1111/jdv.13250
Mannuccio P, Sergio M, Ida H, Massimo M (2015) Effects on health of air pollution: a narrative review. Intern Emerg Med 10:657–662. https://doi.org/10.1007/s11739-015-1276-7
Matés JM, Segura JA, Alonso FJ, Márquez J (2010) Free radical biology & medicine roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms. Free Radic Biol Med 49:1328–1341. https://doi.org/10.1016/j.freeradbiomed.2010.07.028
McCarthy JT, Pelle E, Dong K et al (2013) Letter to the editor effects of ozone in normal human epidermal keratinocytes. Exp Dermatol 22:360–361. https://doi.org/10.1111/exd.12125
Mendola P, Selevan SG, Gutter S, Rice D (2002) Environmental factors associated with a spectrum of neurodevelopmental deficits. Ment Retard Dev Disabil Res Rev 8:188–197. https://doi.org/10.1002/mrdd.10033
Menichin E (1992) Urban air pollution by polycyclic aromatic hydrocarbons: levels and sources of variability. Sci Total Envivron 116(1–2):109–135
Messner B, Knoflach M, Seubert A et al (2009) Cadmium is a novel and independent risk factor for early atherosclerosis mechanisms and in vivo relevance. Arterioscler Thromb Vasc Biol 29:1392–1398. https://doi.org/10.1161/ATVBAHA.109.190082
Michielsen CCPPC, Van Loveren AH, Vos JG (1999) The role of the immune system in hexachlorobenzene-lnduced toxicity. Environ Health Perspect 107:783–792
Migliore L, Coppedè F (2009) Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutat Res Toxicol Environ Mutagen 674:73–84. https://doi.org/10.1016/j.mrgentox.2008.09.013
Milioni ALV, Nagy BV et al (2017) NeuroToxicology Full length article Neurotoxic impact of mercury on the central nervous system evaluated by neuropsychological tests and on theautonomic nervous system evaluated by dynamic pupillometry. Neurotoxicology 59:263–269. https://doi.org/10.1016/j.neuro.2016.04.010
Mohorovic L, Petrovic O, Haller H, Micovic V (2010) Pregnancy loss and maternal methemoglobin levels: an indirect explanation of the association of environmental toxics and their adverse effects on the mother and the fetus. Int J Environ Res Public Health 7:4203–4212. https://doi.org/10.3390/ijerph7124203
Molina JR, Yang P, Cassivi SD et al (2008) Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 83(5):584–594
Mortimer K, Neugebauer R, Lurmann F et al (2008) Air pollution and pulmonary function in asthmatic children: effects of prenatal and lifetime exposures. Epidemiology 19:550–557
Mustafić H, Jabre P, Caussin C et al (2012) Main air pollutants and myocardial infarction: a systematic review and meta-analysis. JAMA 307:713–721
Næss Ø, Nafstad P, Aamodt G et al (2007) Relation between concentration of air pollution and cause-specific mortality: four-year exposures to nitrogen dioxide and particulate matter pollutants in 470 neighborhoods in Oslo, Norway. Am J Epidemiol 165:435–443. https://doi.org/10.1093/aje/kwk016
Nagel G, Stafoggia M, Pedersen M et al (2018) Air pollution and incidence of cancers of the stomach and the upper aerodigestive tract in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Int J Cancer 143:1632–1643. https://doi.org/10.1002/ijc.31564
Nawrot TS, Thijs L, Den Hond EM et al (2002) An epidemiological re-appraisal of the association between blood pressure and blood lead: a meta-analysis. J Hum Hypertens 16:123–131. https://doi.org/10.1038/sj/jhh/1001300
Neidell MJ (2004) Air pollution, health, and socio-economic status: the effect of outdoor air quality on childhood asthma. J Health Econ 23(6):1209–1212
Ni L, Chuang C, Zuo L (2015) Fine particulate matter in acute exacerbation of COPD. Front Physiol 6:294. https://doi.org/10.3389/fphys.2015.00294
Nieuwenhuijsen MJ, Basagaña X, Dadvand P et al (2014) Air pollution and human fertility rates. Environ Int 70:9–14. https://doi.org/10.1016/j.envint.2014.05.005
Nikolić MD, Nikić AS (2008) Effects of air pollution on red blood cells in children. Polish J Environ Stud 17:267–271
Novey S, Wells ID, Tech BS (1983) Asthma and IgE antibodies induced by chromium and nickel salts. J Allergy Clin Immunol 72:407–412
Nyberg F, Gustavsson P, Ja L et al (2000) Urban air pollution and lung cancer in stockholm. Epidemiology 11:487–495
Oberdörster G, Utell MJ (2002) Ultrafine particles in the urban air: to the respiratory tract- and beyond? Environ Health Perspect 110(8):A440–A441
Oberdörster G, Oberdörster E, Oberdörster J (2005) Review nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823–839. https://doi.org/10.1289/ehp.7339
Opstelten JL, Beelen RMJ, Leenders M, Hoek G (2016) Exposure to ambient air pollution and the risk of inflammatory bowel disease: a European nested case – control study. Dig Dis Sci 61:2963–2971. https://doi.org/10.1007/s10620-016-4249-4
Pedersen EB, Jørgensen ME, Pedersen MB et al (2005) Blood and 24-h ambulatory blood. Am J Hypertens 18:612–618. https://doi.org/10.1016/j.amjhyper.2004.11.022
Pekkanen J, Brunner EJ, Anderson HR et al (2000) Daily concentrations of air pollution and plasma fibrinogen in London. Occup Environ Med 57:818–822
Penning TM (1993) Dihydrodiol dehydrogenase and its role in polycyclic aromatic hydrocarbon metabolism. Chem Biol Interact 89:1–34
Pereyra-Muñoz N, Rugerio-Vargas C, Angoa-Pérez M et al (2006) Oxidative damage in substantia nigra and striatum of rats chronically exposed to ozone. J Chem Neuroanat 31:114–123. https://doi.org/10.1016/j.jchemneu.2005.09.006
Perez-Padilla R, Schilmann A, Riojas-Rodriguez H (2010) Respiratory health effects of indoor air pollution. Int J Tuberc Lung Dis 14:1079–1086
Perin PM, Maluf M, Czeresnia CE, Januário DANF, Saldiva PHN (2010a) Impact of short-term preconceptional exposure to particulate air pollution on treatment outcome in couples undergoing in vitro fertilization and embryo transfer (IVF/ET). J Assist Reprod Genet 27(7):371–382
Perin PM, Maluf M, Czeresnia CE et al (2010b) Effects of exposure to high levels of particulate air pollution during the follicular phase of the conception cycle on pregnancy outcome in couples undergoing in vitro fertilization and embryo transfer. Fertil Steril 93(1):301–303
Peters A, Döring A, Wichmann H, Koenig W (1997) Increased plasma viscosity during an air pollution episode: a link to mortality? Lancet 349(349):1582–1587
Pirkle JL, Schwartz J, Landis JR et al (1985) The relationship between blood lead levels and blood pressure and its cardiovascular risk implications. Am J Epidemiol 121:246–258
Ponka A, Virtanen M (1996) Low-level air pollution and hospital admissions for cardiac and cerebrovascular diseases in Helsinki. Am J Public Health 86:1273–1280
Pope CAP III, Burnett RT, Thun MJ et al (2002) Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA 287:1132–1141
Pope CA III, Bhatnagar A, McCracken JP et al (2016) Exposure to fine particulate air pollution is associated with endothelial injury and systemic inflammation. Circ Res 119(11):1204–1214
Power MC, Weisskopf MG, Alexeeff SE et al (2011) Traffic-related air pollution and cognitive function in a cohort of older men. Environ Health Perspect 119:682–687. https://doi.org/10.1289/ehp.1002767
Puri P, Hospital S, Kumar SN (2017) Effects of air pollution on the skin: a review. Indian J Dermatol Venereol Leprol 83:415. https://doi.org/10.4103/0378-6323.199579
Raaschou-Nielsen O, Bak H, Sørensen M et al (2010) Air pollution from traffic and risk for lung cancer in three Danish cohorts. Cancer Epidemiol Prev Biomarkers 19:1284–1292. https://doi.org/10.1158/1055-9965.EPI-10-0036
Rahman M, Tondel M, Ahmad SA (1999) Hypertension and arsenic exposure in Bangladesh. Hypertens Arsen Expo Bangladesh Hypertens 33:74–78. https://doi.org/10.1161/01.HYP.33.1.74
Revis NW, Zinsmeister AR, Bull R (1981) Atherosclerosis and hypertension induction by lead and cadmium ions: an effect prevented by calcium ion. Proc Natl Acad Sci 78:6494–6498
Rezazadeh H, Athar M (1997) Evidence that iron-overload promotes induced skin tumorigenesis in mice. Redox Rep 3:303–309. https://doi.org/10.1080/13510002.1997.11747127
Ritz B, Yu F, Chapa G, Fruin S (2000) Effect of air pollution on preterm birth among children born in Southern California between 1989 and 1993. Epidemiology 11:502–511
Rivas-Arancibia S, Guevara-Guzma R, Lo Y et al (2010) Oxidative stress caused by Ozone exposure induces loss of brain repair in the hippocampus of adult rats. Toxicol Sci 113:187–197. https://doi.org/10.1093/toxsci/kfp252
Rivas-Arancibiaa S, Dorado-Martíneza C, Colin-Barenquea L et al (2003) Effect of acute ozone exposure on locomotor behavior and striatal function. Pharmacol Biochem Behav 74:891–900. https://doi.org/10.1016/S0091-3057(03)00011-X
Rokadia HK, Agarwal S (2013) Serum heavy metals and obstructive lung disease results from the national health and nutrition examination survey. Chest 143:388–397. https://doi.org/10.1378/chest.12-0595
Rousseau MC, Parent ME, Nadon L et al (2007) Occupational exposure to lead compounds and risk of cancer among men: a population-based case-control study. Am J Epidemiol 166:1005–1014. https://doi.org/10.1093/aje/kwm183
Rückerl R, Schneider A, Breitner S et al (2011) Health effects of particulate air pollution: a review of epidemiological evidence. Inhal Toxicol 23(10):555–592
Ruzzin J (2012) Public health concern behind the exposure to persistent organic pollutants and the risk of metabolic diseases. BMC Public Health 12(1):298. https://doi.org/10.1186/1471-2458-12-298
Salnikow K, Zhitkovich A (2008) Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic and chromium. Chem Res Toxicol 21:28–44. https://doi.org/10.1021/tx700198a.Genetic
Salonen JT, Seppänen K, Nyyssönen K et al (1995) Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation 91
Salvi SS, Barnes PJ (2009) Chronic obstructive pulmonary disease in non-smokers. Lancet 374:733–743. https://doi.org/10.1016/S0140-6736(09)61303-9
Salvi S, Blomberg A, Rudell B et al (1999) Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am J Respir Crit Care Med 159(3):702–709
Samoli E, Nastos PT, Paliatsos AG et al (2011) Acute effects of air pollution on pediatric asthma exacerbation: evidence of association and effect modification. Environ Res 111(3):418–424
Santibanez M, Alguacil J, Garcı M et al (2012) Occupational exposures and risk of stomach cancer by histological type. Occup Environ Med 69:268–275. https://doi.org/10.1136/oemed-2011-100071
Santucci D, Sorace A, Francia N et al (2006) Prolonged prenatal exposure to low-level ozone affects aggressive behaviour as well as NGF and BDNF levels in the central nervous system of CD-1 mice. Behav Brain Res 166:124–130. https://doi.org/10.1016/j.bbr.2005.07.032
Saxena P (2015) Seasonal variation of isoprene emissions from tropical roadside plant species and their possible role in deteoriating air quality. Environ Skeptics Critics 4(2):67
Saxena P, Ghosh C (2012) A review of assessment of benzene, toluene, ethylbenzene and xylene (BTEX) concentration in urban atmosphere of Delhi. Int J Phys Sci 7(6):850–860
Saxena P, Ghosh C (2015) A sustainable approach towards minimizing atmospheric benzene by the use of plants. Int J Agric Crop Sci 8(3):495–502
Saxena P, Ghosh C (2019) Establishing correlation between abiotic stress and isoprene emission of selected plant species. In: Emerging issues in ecology and environmental science. Springer, Cham, pp 43–65
Saxena P, Sonwani S (2019a) Primary criteria air pollutants: environmental health effects. In: Criteria air pollutants and their impact on environmental health. Springer, Singapore, pp 49–82
Saxena P, Sonwani S (2019b) Secondary criteria air pollutants: environmental health effects. In: Criteria air pollutants and their impact on environmental health. Springer, Singapore, pp 83–126
Schäfer T, Ring J (1997) Epidemiology of allergic diseases. Allergy 52:14–22
Schäfer T, Nienhaus A, Vieluf D et al (2001) Epidemiology of acne in the general population: the risk of smoking. Br J Dermatol 145(1):100–104
Schultz MG, Schröder S, Lyapina O, Cooper OR, Galbally I, Petropavlovskikh I, … Seguel RJ (2017) Tropospheric Ozone assessment report: database and metrics data of global surface ozone observations. Elementa: Science of the Anthropocene 5
Schwela D (2000) Air pollution and health in urban areas. Rev Environ Health 15:13–42
Seaton A, Godden D, MacNee W, Donaldson K (1995) Particulate air pollution and acute health effects. Lancet 345:176–178
Seltzer J, Bigby BG, Stulbarg M et al (1986) O3-induced change in bronchial reactivity to methacholine and airway inflammation in humans. J Appl Physiol 60:1321–1326
Sethi S, Murphy TF (2001) Bacterial infection in chronic obstructive pulmonary disease in 2000: a state-of-the-art review. Clin Microbiol Rev 14:336–363. https://doi.org/10.1128/CMR.14.2.336
Shah ASV, Langrish JP, Nair H et al (2013) Global association of air pollution and heart failure: a systematic review and meta-analysis. Lancet 382:1039–1048. https://doi.org/10.1016/S0140-6736(13)60898-3
Shrivastava D, Nayak B, Kant S, Panda J (2017) A review on health impacts of air pollutants with a special mention to Eastern Parts of India, a growing hub for diseases. Int J Earth Atmos Sci 4:21–33
Shulman JM, De Jager PL, Feany MB (2011) Parkinson’s disease: genetics and pathogenesis. Annu Rev Pathol Mech Dis 6:193–224. https://doi.org/10.1146/annurev-pathol-011110-130242
Slama R, Bottagisi S, Solansky I, Lepeule J (2013) Short-term impact of atmospheric pollution on fecundability. Epidemiology 24:871–879. https://doi.org/10.1097/EDE.0b013e3182a702c5
Smith-Sivertsen T, Diaz E, Pope D et al (2009) Original contribution effect of reducing indoor air pollution on women’ s respiratory symptoms and lung function: the respire randomized trial, Guatemala. Am J Epidemiol 170:211–220. https://doi.org/10.1093/aje/kwp100
Solenkova NV, Newman JD, Berger JS et al (2014) Metal pollutants and cardiovascular disease: mechanisms and consequences of exposure. Am Heart J 168:812–822. https://doi.org/10.1016/j.ahj.2014.07.007
Sonwani S, Kulshreshtha U (2016) Particulate matter levels and it’s associated health risks in East Delhi. Proceedings of Indian aerosol science and technology association conference on aerosol and climate change: insight and challenges. IASTA Bull 22(1–2). ISSN 09714510
Sonwani S, Kulshrestha U (2018) Morphology, elemental composition and source identification of airborne particles in Delhi, India. J Indian Geophys Union 22(6):607–620
Sonwani S, Kulshrestha UC (2019) PM 10 carbonaceous aerosols and their real-time wet scavenging during monsoon and non-monsoon seasons at Delhi, India. J Atmos Chem 76:171–200
Sonwani S, Saxena P (2016) Identifying the sources of primary air pollutants and their impact on environmental health: a review. IJETR 6(2):111–130
Sonwani S, Amreen H, Khillare PS (2016) Polycyclic Aromatic Hydrocarbons (PAHs) in urban atmospheric particulate of NCR, Delhi, India. In 41st COSPAR Scientific Assembly (vol. 41)
Sood A (2012) Indoor fuel exposure and the lung in both developing and developed countries: an update. Clin Chest Med 33(4):649–665. https://doi.org/10.1016/j.ccm.2012.08.003
Sorace A, De Acetis L, Alleva E et al (2001) Prolonged exposure to low doses of ozone: short- and long-term changes in behavioral performance in mice. Environ Res 85:122–134. https://doi.org/10.1006/enrs.2000.4097
Squibb KS, Fowler BA (1981) Relationship between metal toxicity to subcellular systems and the carcinogenic response. Environ Health Perspect 40:181–188
Srám RJ, Binková B, Dejmek J, Bobak M (2005) Ambient air pollution and pregnancy outcomes: a review of the literature. Environ Health Perspect 113:375–382. https://doi.org/10.1289/ehp.6362
Steenland K, Boffetta P (2000) Lead and cancer in humans: where are we now? Am J Ind Med 38:295–299
Sunyer J (2008) The neurological effects of air pollution in children. Eur Respir Soc 32:535–537. https://doi.org/10.1183/09031936.00073708
Sunyer J, Spix C, Que P et al (1997) Urban air pollution and emergency admissions for asthma in four European cities: the APHEA Project. Thorax 52:760–765
Sze MA, Hogg JC, Sin DD (2014) Bacterial microbiome of lungs in COPD. Int J Chron Obstruct Pulmon Dis 9:229–238
Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ (2012) Heavy metal toxicity and the environment. In: Luch A (ed) Molecular, clinical and environmental toxicology. experientia supplementum, vol 101. Springer, Basel
Tellez-plaza M, Navas-acien A, Crainiceanu CM et al (2008) Cadmium exposure and hypertension in the 1999–2004 National Health and Nutrition Examination Survey (NHANES). Environ Health Perspect 116:51–56. https://doi.org/10.1289/ehp.10764
Thiele JJ, Podda M, Packer L (1997) Tropospheric Ozone: an emerging environmental stress to skin. Biol Chem 378:1299–1305
Thurlbeck WM, Foley FD (1963) Experimental pulmonary emphysema: the effect of intratracheal injection of cadmium chloride solution in the guinea pig. Am J Pathol 42(4):431–441
Torre LA, Bray F, Siegel RL, Ferlay J (2015) Global cancer statistics, 2012. CA Cancer J Clin 65:87–108. https://doi.org/10.3322/caac.21262
Torres AD, Rai AN, Hardiek ML (2000) Mercury intoxication and arterial hypertension: report of two patients and review of the literature. Pediatrics 105:e34–e34
Torres-Duque C, Maldonado D, Pérez-Padilla R, Ezzati M, Viegi G (2008) Biomass fuels and respiratory diseases: a review of the evidence. Proc Am Thorac Soc 5(5):577–590. https://doi.org/10.1513/pats.200707-100RP
Tsai SS, Goggins WB, Chiu HF, Yang CY (2003) Evidence for an association between air pollution and daily stroke admissions in Kaohsiung, Taiwan. Stroke 34(11):2612–2616
Tuder RM, Mcgrath S, Neptune E (2003) The pathobiological mechanisms of emphysema models: What do they have in common? Pulm Pharmacol Ther 16:67–78. https://doi.org/10.1016/S1094-5539(02)00099-8
Türk YA, Kavraz M (2011) Air pollutants and its effects on human healthy: the case of the city of Trabzon. In Advanced topics in environmental health and air pollution case studies. InTech
Urch B, Silverman F, Corey P et al (2005) Acute blood pressure responses in healthy adults during controlled air pollution exposures. Environ Health Perspect 113:1052–1055. https://doi.org/10.1289/ehp.7785
Valacchi G, Sticozzi C, Pecorelli A et al (2012) Cutaneous responses to environmental stressors. Ann N Y Acad Sci 1271:75–81. https://doi.org/10.1111/j.1749-6632.2012.06724.x
Vaziri ND, Liang K, Ding Y (1999) Increased nitric oxide inactivation by reactive oxygen species in lead-induced hypertension. Kidney Int 56:1492–1498. https://doi.org/10.1046/j.1523-1755.1999.00670.x
Vierkotter A, Schikowski T, Ranft U et al (2010) Airborne particle exposure and extrinsic skin aging. J Invest Dermatol 130:2719–2726. https://doi.org/10.1038/jid.2010.204
Villeneuve PJ, Chen L, Stieb D, Rowe BH (2006) Associations between outdoor air pollution and emergency department visits for stroke in Edmonton, Canada. Eur J Epidemiol 21:689–700. https://doi.org/10.1007/s10654-006-9050-9
Wang L, Pinkerton KE (2007) Air pollutant effects on fetal and early postnatal development. Birth Defects Res C Embryo Today 81(3):144–154
Wang S, Shi X (2001) Molecular mechanisms of metal toxicity and carcinogenesis. Mol Cell Biochem 222:3–9
Wang Y, Tian Z, Zhu H, Cheng Z, Kang M, Luo C, Zhang G (2012) Polycyclic aromatic hydrocarbons (PAHs) in soils and vegetation near an e-waste recycling site in South China: concentration, distribution, source, and risk assessment. Sci Total Environ 439:187–193. https://doi.org/10.1016/j.scitotenv.2012.08.018
Wang S, Nan J, Shi C, et al (2015) Atmospheric ammonia and its impacts on regional air quality over the megacity of Shanghai, China. Nat Publ Gr 1–13. https://doi.org/10.1038/srep15842
Wellenius GA, Schwartz J, Mittleman MA (2005a) Air pollution and hospital admissions for ischemic and hemorrhagic stroke among medicare beneficiaries. Stroke 36:2549–2553. https://doi.org/10.1161/01.STR.0000189687.78760.47
Wellenius GA, Bateson TF, Mittleman MA et al (2005b) Particulate air pollution and the rate of hospitalization for congestive heart failure among medicare beneficiaries in Pittsburgh, Pennsylvania. Am J Epidemiol 161(11):1030–1036
Weuve J, Puett RC, Schwartz J et al (2012) Exposure to particulate air pollution and cognitive decline in older women. Arch Intern Med 172:219–227
Williams GR (1983) Presidential address: a history of appendicitis: with anecdotes illustrating its importance. Ann Surg 197(5):495
Williams NM, Jackson D, Everson NW et al (1998) Is the incidence of acute appendicitis really falling? Ann R Coll Surg Engl 80(2):122
Wlaschek M, Tantcheva-Poór I, Naderi L (2001) Solar UV irradiation and dermal photoaging. J Photochem Photobiol B Biol 63(1–3):41–51
World Health Organization (WHO) (2000) Air quality guidelines for Europe 2nd edition
World Health Organization (WHO) (2005) Indoor air pollution from solid fuels and risk of low birth weight and stillbirth
World Health Organization (WHO) (2010) Persistent organic pollutants: impact on child health
World Health Organization (WHO) (2014). https://www.who.int/mediacentre/news/releases/2014/air-pollution/en/
Wu K, Chang C, Yen C, Lai C (2019) Associations between environmental heavy metal exposure and childhood asthma: a population-based study. J Microbiol Immunol Infect 52(2):352–362. https://doi.org/10.1016/j.jmii.2018.08.001
Xu F, Yan S, Wu M et al (2011) Ambient ozone pollution as a risk factor for skin disorders. Br J Dermatol 165(1):224–225
Zeng X, Xu X, Zheng X et al (2016) Heavy metals in PM 2.5 and in blood, and children’s respiratory symptoms and asthma from an e-waste recycling area. Environ Pollut 210:346–353. https://doi.org/10.1016/j.envpol.2016.01.025
Zhang JJ, Smith KR (2003) Indoor air pollution: a global health concern. Br Med Bull 68:209–225. https://doi.org/10.1093/bmb/ldg029
Zhang Y, Ji X, Ku T, Sang N (2015) Inflammatory response and endothelial dysfunction in the hearts of mice co-exposed. Environ Toxicol 31:1996–2005. https://doi.org/10.1002/tox
Zheng JJ, Zhu XS, Huangfu Z et al (2005) Crohn’s disease in mainland China: a systematic analysis of 50 years of research. Chinese J Dig Dis 6(4):175–181
Zhou N, Fu Z, Sun T (2008) Neuroscience letters effects of different concentrations of oxygen ozone on rat’s astrocytes in vitro. Neurosci Lett 441:178–182. https://doi.org/10.1016/j.neulet.2008.06.036
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Singh, N. (2020). Air Pollution Exposure Studies Related to Human Health. In: Saxena, P., Srivastava, A. (eds) Air Pollution and Environmental Health. Environmental Chemistry for a Sustainable World, vol 20. Springer, Singapore. https://doi.org/10.1007/978-981-15-3481-2_7
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