Abstract
Evidence is growing that N-linked glycans play pivotal roles in protein folding and intra- or intercellular trafficking of proteins. In addition, it is known that significant amounts of free oligosaccharides (fOSs) are generated in the lumen of the endoplasmic reticulum (ER) during protein N-glycosylation. fOSs are also formed in the cytosol by enzymatic deglycosylation of misfolded glycoproteins. In this chapter, an overview of the current understanding of the generation of high mannose-type fOSs bearing high mannose-type glycans in mammals and yeast is provided.
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Suzuki, T. (2015). Free Oligosaccharides (High Mannose-Type Free Glycans Found in Mammals and Yeast). In: Taniguchi, N., Endo, T., Hart, G., Seeberger, P., Wong, CH. (eds) Glycoscience: Biology and Medicine. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54841-6_155
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DOI: https://doi.org/10.1007/978-4-431-54841-6_155
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Publisher Name: Springer, Tokyo
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Online ISBN: 978-4-431-54841-6
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