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The Role of Blood and Plasma Viscosity in Restoring Oxygen Delivery Capacity

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Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics

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Abstract

It is a generalized perception that blood products are needed when oxygen (O2) delivery capacity is jeopardized by the decrease of blood’s intrinsic O2 carrying capacity due to the decrease of hematocrit (Hct) or blood hemoglobin.

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Acknowledgments

Study supported in part by USPHS Bioengineering Research Partnership grant R24-HL 064395 (MI), and grants R01-HL 062354 (MI), R01-HL 076182 (PC) and USAMRAA award W81XWH1120012 (AGT).

Author information

Authors and Affiliations

  1. Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA

    Amy G. Tsai, Beatriz Y. Salazar Vázquez, Pedro Cabrales & Marcos Intaglietta

  2. Department of Anesthesia and Intensive Care Medicine, Innsbruck Medical University, Innsbruck, Austria

    Judith Martini

  3. Department of Experimental Medicine, Faculty of Medicine, Universidad Nacional Autónoma de México, Hospital General de México, México D.F, Mexico

    Beatriz Y. Salazar Vázquez

  4. Facultad de Medicina y Nutrición, Universidad Juárez del Estado de Durango, Durango, Mexico

    Beatriz Y. Salazar Vázquez

  5. Department of Hematology and Medicine, Albert Einstein College of Medicine, Bronx, NY, USA

    Seetharama A. Acharya

Authors
  1. Amy G. Tsai
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  2. Judith Martini
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  3. Beatriz Y. Salazar Vázquez
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  4. Pedro Cabrales
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  5. Seetharama A. Acharya
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  6. Marcos Intaglietta
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Corresponding author

Correspondence to Marcos Intaglietta .

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Editors and Affiliations

  1. Brown University, Barrington, Rhode Island, USA

    Hae Won Kim

  2. Brown University, Barrington, Rhode Island, USA

    A. Gerson Greenburg

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Tsai, A.G., Martini, J., Salazar Vázquez, B.Y., Cabrales, P., Acharya, S.A., Intaglietta, M. (2013). The Role of Blood and Plasma Viscosity in Restoring Oxygen Delivery Capacity. In: Kim, H., Greenburg, A. (eds) Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40717-8_4

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