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Invasive Pulmonary Aspergillosis in Critically Ill Patients

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Annual Update in Intensive Care and Emergency Medicine 2013

Part of the book series: Annual Update in Intensive Care and Emergency Medicine ((AUICEM))

Abstract

Aspergillus is a ubiquitous fungus that can cause a wide spectrum of diseases including allergy, superficial infection related to (surgical) trauma, and invasive disease [1]. More than 180 species of Aspergillus have been described but A. fumigatus is most likely to cause disease as it is responsible for about 90 % of cases of invasive aspergillosis. The mechanism of infection is represented by aerosolized conidia by which these organisms spread in the environment and cause pulmonary infection after inhalation. Growth into angio-invasive filamentous forms results in local pulmonary inflammation, invasion, and eventually hematogenous spread to distal organs [1].

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Authors and Affiliations

  1. Dept. of Internal Medicine, Ghent University, Ghent, Belgium

    S. Blot

  2. Attikon University Hospital, Dept. of Critical Care Medicine, University of Athens Medical School, Athens, Greece

    D. Koulenti & G. Dimopoulos

Authors
  1. S. Blot
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  2. D. Koulenti
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  3. G. Dimopoulos
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Correspondence to S. Blot .

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Editors and Affiliations

  1. Erasme Hospital, Université libre de Bruxelles, Brussels, Belgium

    Jean-Louis Vincent Prof.

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Blot, S., Koulenti, D., Dimopoulos, G. (2013). Invasive Pulmonary Aspergillosis in Critically Ill Patients. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2013. Annual Update in Intensive Care and Emergency Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35109-9_5

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  • DOI: https://doi.org/10.1007/978-3-642-35109-9_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35108-2

  • Online ISBN: 978-3-642-35109-9

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