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In Vitro Assay Systems for the Assessment of Oestrogenicity

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Plastics in Dentistry and Estrogenicity

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Abstract

Exogenous compounds behaving similarly to the endogenous estrogens are called xenoestrogens, and their intake by humans or animals may interfere with the normal hormonal balance of the organism. Especially in dental practice, there are many products such as restorative materials, liners, adhesives, oral prosthetic devices, tissue substitutes and rebase materials, which may possess oestrogenic activity, most important among them being bisphenol-A (BPA). This chapter is focusing on the presentation of the in vitro assays used in the literature for the assessment of the oestrogenicity of various compounds with an emphasis on those used in dental practice.

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Authors and Affiliations

  1. Laboratory for Cell Proliferation and Ageing, Institute of Biosciences and Applications, NCSR “Demokritos”, 15310, Athens, Greece

    Harris Pratsinis & Dimitris Kletsas

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  1. Harris Pratsinis
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  2. Dimitris Kletsas
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Correspondence to Dimitris Kletsas .

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  1. Department of Orthodontics, University of Zurich Center of Dental Medicine, Zurich, Switzerland

    Theodore Eliades

  2. Dept. of Dental Materials, University of Athens School o Dentistry, Athens, Greece

    George Eliades

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Pratsinis, H., Kletsas, D. (2014). In Vitro Assay Systems for the Assessment of Oestrogenicity. In: Eliades, T., Eliades, G. (eds) Plastics in Dentistry and Estrogenicity. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29687-1_3

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  • DOI: https://doi.org/10.1007/978-3-642-29687-1_3

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