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Moya-moya Disease

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Textbook of Pediatric Neurosurgery

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Abstract

Moyamoya disease is progressive occlusion of bilateral distal carotid arteries with the formation of collateral circulations. There is critical balance between perfusion delay and stress. Although the cause of Moyamoya disease has been still under investigation, there are debates about the most effective treatment method especially between indirect and direct revascularization. Ischemic attacks and hemorrhage are two major problems of this complicated disease. Revascularization is one of the methods of choice to prevent further ischemic insults but still debating its efficacy on hemorrhagic attack. Repeated ischemic and hemorrhagic insults will accumulate damages in the brain and deteriorate the neurological and functional status of Moyamoya patients. Due to its progressive nature, early diagnosis and timely management for repeated attack, whether it could be ischemic or hemorrhagic, are tremendously important. The critical treatment for the cause of Moyamoya disease hopes to come soon.

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Authors and Affiliations

  1. Department of Pediatric Neurosurgery, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, South Korea

    Kyu Won Shim, Eun Kyung Park & Dong Seok Kim

  2. Department of Neurosurgery, CHA Medical Center, CHA University, Bundang, South Korea

    Joong Uhn Choi

  3. Department of Neurosurgery, Severance Children’s Hospital, Yonsei University College of Medicine, 50 Yonseiro, Seodaemungu, Seoul, South Korea

    Dong Seok Kim

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  1. Kyu Won Shim
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  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, California, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, Ontario, Canada

    James T. Rutka

Section Editor information

  1. Director of Pediatric Neurosurgery, International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

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© 2017 Springer International Publishing AG

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Shim, K.W., Park, E.K., Choi, J.U., Kim, D.S. (2017). Moya-moya Disease. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_54-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_54-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-31512-6

  • Online ISBN: 978-3-319-31512-6

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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