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Memory Disruption Following Traumatic Brain Injury

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The Neurobiological Basis of Memory

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Abstract

Traumatic brain injury (TBI) is a major public health concern worldwide, and is the leading cause of disability and death in children and young adults. One of the most common consequences of TBI is cognitive impairment, including deficits in memory and executive function. Although some recovery of function is typical after injury, many individuals are left with lifelong memory problems. Therefore, it is important to understand how the brain’s memory systems are affected by various types of TBI. Such knowledge will improve our ability to understand what memory functions are most vulnerable to injury and then to use this information to develop more effective treatments and rehabilitation strategies to improve cognitive outcome. This chapter reviews studies of memory loss following TBI, with a focus on studies in animal models of brain injury and how results from these studies have shaped our understanding of the mechanisms and consequences of TBI on the brain’s memory systems. The chapter also considers how understanding the organization of multiple memory systems is shaping current research in the field, and describes recent studies based on the Kesner attribute model that provide new insights into how TBI affects memory and cognition.

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Authors and Affiliations

  1. Department of Neurological Surgery, University of California Davis, 1515 Newton Ct., 95619, Davis, CA, USA

    Robert F. Berman PhD, Bruce G. Lyeth PhD & Gene G. Gurkoff PhD

  2. Department of Neurological Surgery, U.C Davis School of Medicine, 95817, Sacramento, CA, USA

    Kiarash Shahlaie MD, PhD

Authors
  1. Robert F. Berman PhD
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  2. Bruce G. Lyeth PhD
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  3. Kiarash Shahlaie MD, PhD
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  4. Gene G. Gurkoff PhD
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Corresponding author

Correspondence to Robert F. Berman PhD .

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Editors and Affiliations

  1. Department of Psychology, Radford University, Radford, Virginia, USA

    Pamela A. Jackson

  2. Department of Cognitive Science, University of California-San Diego, La Jolla, California, USA

    Andrea A. Chiba

  3. Department of Neurological Surgery and Center for Neuroscience, University of California-Davis, Davis, California, USA

    Robert F. Berman

  4. Department of Psychology, University of Illinois at Chicago, Chicago, Illinois, USA

    Michael E. Ragozzino

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Berman, R., Lyeth, B., Shahlaie, K., Gurkoff, G. (2016). Memory Disruption Following Traumatic Brain Injury. In: Jackson, P., Chiba, A., Berman, R., Ragozzino, M. (eds) The Neurobiological Basis of Memory. Springer, Cham. https://doi.org/10.1007/978-3-319-15759-7_13

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