Skip to main content

Abstract

Lactose is the principal carbohydrate in the milk of most mammals, exceptions are the California sea lion and the hooded seal, which are the only significant sources. Milk contains only trace amounts of other sugars, including glucose (50 mg/l) and fructose and glucosamine, galactosamine and N-acetyl neuraminic acid as components of glycoproteins and glycolipids. The milk of all species that have been studied contain oligosaccharides which are major constituents of the milk of some species, including human. This chapter will concentrate on the chemistry and properties of lactose with a short section on oligosaccharides.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Affertsholt-Allen, T. (2007). Market developments and industry challenges for lactose and lactose derivatives. IDF lactose symposium, 14–16 May. Moscow, Russia.

    Google Scholar 

  • Andrews, G. (1989). Lactulose in heated milk. In P. F. Fox (Ed.), Heat-induced changes in milk, bulletin 238 (pp. 45–52). Brussels: International Dairy Federation.

    Google Scholar 

  • Becker, C. J., & Lowe, J. R. (2003). Fucose: Biosynthesis and biological function in mammals. Glycobiology, 13, 41R–53R.

    Article  CAS  Google Scholar 

  • Ganzle, M. G. (2011a). Lactose derivatives. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 202–208). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Ganzle, M. G. (2011b). Galactooligosaccharides. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 209–216). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Holt, C. (1985). The milk salts. Their secretion, concentrations and physical chemistry. In P. F. Fox (Ed.), Developments in dairy chemistry (Lactose and minor constituents, Vol. 3, pp. 143–181). London: Elsevier Applied Science.

    Chapter  Google Scholar 

  • Hynd, J. (1980). Drying of whey. Journal of the Society of Dairy Technology, 33, 52–54.

    Article  Google Scholar 

  • Ingram, C. J. E., & Swallow, D. M. (2009). Lactose intolerance. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3, pp. 203–229). New York: Springer.

    Chapter  Google Scholar 

  • Jenness, R., & Holt, C. (1987). Casein and lactose concentrations in milk of 31 species are negatively correlated. Experimentia, 43, 1015–1018.

    Article  CAS  Google Scholar 

  • Jenness, R., & Patton, S. (1959). Lactose. In Principles of dairy chemistry (pp. 73-100). New York: Wiley

    Google Scholar 

  • Jenness, R., & Sloan, R. E. (1970). The composition of milk of various species: A review. Dairy Science Abstracts, 32, 599–612.

    Google Scholar 

  • Kunz, C., & Rudloff, S. (2006). Health promoting aspects of milk oligosaccharides. A review. International Dairy Journal, 16, 1341–1346.

    Article  CAS  Google Scholar 

  • Ley, J. M., & Jenness, R. (1970). Lactose synthetase activity of α-lactalbumins from several species. Archives of Biochemistry and Biophysics, 138, 464–469.

    Article  CAS  Google Scholar 

  • Mahoney, R. R. (1997). Lactose: Enzymatic modification. In P. F. Fox (Ed.), Advanced dairy chemistry – 3 – lactose, water, salts and vitamins (2nd ed., pp. 77–125). London: Chapman & Hall.

    Google Scholar 

  • Martinez-Ferez, A., Rudloff, S., Gaudix, A., Henkel, C. A., Pohlentz, G., Boza, J. J., Gaudix, E. M., & Kunz, C. (2006). Goats’ milk as a natural source of lactose-derived oligosaccharides: Isolation by membrane technology. International Dairy Journal, 16, 173–181.

    Article  CAS  Google Scholar 

  • Mehra, R., & Kelly, P. (2006). Milk oligosaccharides: Structural and technological aspects. International Dairy Journal, 16, 1334–1340.

    Article  CAS  Google Scholar 

  • Newberg, D. S., & Newbauer, S. H. (1995). Carbohydrates in milk: Analysis, quantities and significance. In R. G. Jensen (Ed.), Handbook of milk composition (pp. 273–349). San Diego: Academic Press.

    Chapter  Google Scholar 

  • Nursten, H. (2011). Maillard reaction. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 217–235). Oxford: Academic Press.

    Chapter  Google Scholar 

  • O’Brien, J. (1997). Reaction chemistry of lactose: Non-enzymatic degradation pathways and their significance in dairy products. In P. F. Fox (Ed.), Advanced dairy chemistry (Lactose, water, salts and vitamins 2nd ed., Vol. 3, pp. 155–231). London: Chapman & Hall.

    Google Scholar 

  • O’Brien, J. (2009). Non-enzymatic degradation pathways of lactose and their significance in dairy products. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3, pp. 231–294). New York: Springer.

    Chapter  Google Scholar 

  • Oftedal, O. T. (2013). Origin and evolution of the major constituents in milk. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (4th edn, Vol. 1A, pp. 1–42). New York: Springer.

    Chapter  Google Scholar 

  • O’Mahony, J. A., & Touhy, J. J. (2013). Further applications of membrane filtration in dairy processing. In A. Tamime (Ed.), Membrane processing: Dairy and beverage applications (pp. 225–261). West Sussex: Blackwell.

    Google Scholar 

  • Osthoff, G., de Waal, H. O., Hugo, A., de Wit, M., & Botes, P. (2005). Milk composition of a free-ranging African elephant (Loxodonta Africana) cow in early lactation. Comparative Biochemistry and Physiology, 141, 223–229.

    Article  CAS  Google Scholar 

  • Paterson, A. H. J. (2009). Lactose: Production and applications. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 196–201). Oxford: Academic Press.

    Google Scholar 

  • Paterson, A. H. J. (2011). Production and uses of lactose. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3, pp. 105–120). New York: Springer.

    Google Scholar 

  • Playne, M. J., & Crittenden, R. G. (2009). Galactosaccharides and other products derived from lactose. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3, pp. 121–201). New York: Springer.

    Chapter  Google Scholar 

  • Schuck, P. (2011). Lactose crystallization. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 182–195). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Sharp, J. A., Menzies, K., Lefevre, C., & Nicholas, K. R. (2011). Milk of monotremes and marsupial. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 1, pp. 553–562). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Smart, J. B. (1993). Transferase reactions of β-galactosidases – new product opportunities. In Lactose hydrolysis, bulletin 239 (pp. 16–22). Brussels: International Dairy Federation.

    Google Scholar 

  • Swallow, D. M. (2011). Lactose intolerance. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 236–240). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Tamura., Y., Mizota, T., Shimamura, S., & Tomita, M. (1993). Lactulose and its application to food and pharmaceutical industries. In Lactose hydrolysis, bulletin 239 (pp. 43–53) Brussels: International Dairy Federation.

    Google Scholar 

  • Tumerman, L., Fram, H., & Cornely, K. W. (1954). The effect of lactose crystallization on protein stability in frozen concentrated milk. Journal of Dairy Science, 37, 830–839.

    Article  CAS  Google Scholar 

  • Urashima, T., Saito, T., Nakarmura, T., & Messer, M. (2001). Oligosaccharides of milk and colostrums in non-human mammals. Glycoconjugate Journal, 18, 357–371.

    Article  CAS  Google Scholar 

  • Urashima, T., Kitaoka, M., Asakuma, S., & Messer, M. (2009). Indigenous oligosaccharides in milk. In P. L. H. McSweeney & P. F. Fox (Eds.), Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3, pp. 295–349). New York: Springer.

    Chapter  Google Scholar 

  • Urashima, T., Asakuma, S., Kitaoka, M., & Messer, M. (2011). Indigenous oligosaccharides in milk. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.), Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 241–273). Oxford: Academic Press.

    Chapter  Google Scholar 

  • Walstra, P., & Jenness, R. (1984a). Dairy chemistry and physics. New York: Wiley.

    Google Scholar 

Suggested Reading

  • Fox, P. F. (Ed.). (1985). Developments in dairy chemistry – 3 – lactose and minor constituents. London: Elsevier Applied Science Publishers.

    Google Scholar 

  • Fox, P. F. (Ed.). (1997). Advanced dairy chemistry – 3 – lactose, water, salts and vitamins (2nd ed.). London: Chapman & Hall.

    Google Scholar 

  • Fuquay, J. W., Fox, P. F., & McSweeney, P. L. H. (Eds.). (2011). Encyclopedia of dairy sciences (2nd ed., Vol. 3, pp. 173–273). Oxford: Academic Press.

    Google Scholar 

  • Holsinger, V. H. (1988). Lactose. In N. P. Wong (Ed.), Fundamentals of dairy chemistry (pp. 279–342). New York: Van Nostrand Reinhold Co.

    Chapter  Google Scholar 

  • IDF. (1993). Proceedings of the IDF workshop on lactose hydrolysis, bulletin 289. Brussels: International Dairy Federation.

    Google Scholar 

  • Jenness, R., & Patton, S. (1959). Lactose. In Principles of dairy chemistry (pp. 73-100). New York: Wiley.

    Google Scholar 

  • Labuza, T. P., Reineccius, G. A., Monnier, V. M., O’Brien, J., & Baynes, J. W. (Eds.). (1994). Maillard reactions in chemistry, food and health. Cambridge: Royal Society of Chemistry.

    Google Scholar 

  • McSweeney, P. L. H., & Fox, P. F. (Eds.). (2009). Advanced dairy chemistry (Lactose, water, salts and minor constituents 3rd ed., Vol. 3). New York: Springer.

    Google Scholar 

  • Nickerson, T. A. (1965). Lactose. In B. H. Webb & A. H. Johnson (Eds.), Fundamentals of dairy chemistry (pp. 224–260). Westport, CT: AVI Publishing Co. Inc.

    Google Scholar 

  • Nickerson, T. A. (1974). Lactose. In B. H. Webb, A. H. Johnson, & J. A. Alford (Eds.), Fundamentals of dairy chemistry (pp. 273–324). Westport, CT: AVI Publishing Co. Inc.

    Google Scholar 

  • Walstra, P., & Jenness, R. (1984b). Dairy chemistry and physics. New York: Wiley.

    Google Scholar 

  • Walstra, P., Geurts, T. J., Noomen, A., Jellema, A., & van Boekel, M. A. J. S. (1999). Dairy technology: Principles of milk processing and processes. New York: Marcel Dekker, Inc.

    Google Scholar 

  • Walstra, P., Wouters, J. F., & Geurts, T. J. (2006). Dairy science and technology. Boca Raton, FL: CRC Press.

    Google Scholar 

  • Yang, S. T., & Silva, E. M. (1995). Novel products and new technologies for use of a familiar carbohydrate, milk lactose. Journal of Dairy Science, 78, 2541–2562.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Fox, P.F., Uniacke-Lowe, T., McSweeney, P.L.H., O’Mahony, J.A. (2015). Lactose. In: Dairy Chemistry and Biochemistry. Springer, Cham. https://doi.org/10.1007/978-3-319-14892-2_2

Download citation

Publish with us

Policies and ethics