Abstract
During lumbosacral spinal fusion procedures, the overarching goal is to mitigate the risk of new or worsened neurologic deficits secondary to iatrogenic nerve root or lumbosacral plexus injury. One objective is to avoid direct mechanical irritation or insult to neural elements using spontaneous and triggered electromyography (EMG) to detect proximity of surgical instruments and implants. While an 8-mA threshold for pedicle screw testing remains the most prudent alert criterion, it should be adjusted based on patient factors such as bone porosity. A second objective is to alert the surgeon to possible evolving dysfunction. EMG and somatosensory-evoked potentials (SSEPs) have historically shown relatively weak sensitivity in diagnosing spinal nerve root dysfunction during surgery, while motor-evoked potentials (MEPs) have demonstrated excellent accuracy when appropriate alert criteria and optimized anesthetic regimens are utilized. IONM professionals should be aware of the strengths and limitations of each test modality, and, based on diagnosis, procedure, and patient factors, advocate for a multimodality approach to maximize diagnostic accuracy and potential therapeutic impact of IONM.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Epstein NE. Many intraoperative monitoring modalities have been developed to limit injury during extreme lateral interbody fusion (XLIF/MIS XLIF): does that mean XLIF/MIS XLIF are unsafe? Surg Neurol Int. 2019;10:233.
Lieberman JA, Lyon R, Jasiukaitis P, Berven SH, Burch S, Feiner J. The reliability of motor evoked potentials to predict dorsiflexion injuries during lumbosacral deformity surgery: importance of multiple myotomal monitoring. Spine J. 2019;19(3):377–85.
de Kunder SL, van Kuijk SMJ, Rijkers K, Caelers IJMH, van Hemert WLW, de Bie RA, et al. Transforaminal lumbar interbody fusion (TLIF) versus posterior lumbar interbody fusion (PLIF) in lumbar spondylolisthesis: a systematic review and meta-analysis. Spine J. 2017;17(11):1712–21.
Wilent WB, Tesdahl EA, Harrop JS, Welch WC, Cannestra AF, Poelstra KA, et al. Utility of motor evoked potentials to diagnose and reduce lower extremity motor nerve root injuries during 4,386 extradural posterior lumbosacral spine procedures. Spine J. 2019;20(2):191–8.
Isley MR, Zhang X-F, Balzer JR, Leppanen RE. Current trends in pedicle screw stimulation techniques: lumbosacral, thoracic, and cervical levels. Neurodiagn J. 2012;52(2):100–75.
Leppanen RE. Intraoperative monitoring of segmental spinal nerve root function with free-run and electrically-triggered electromyography and spinal cord function with reflexes and F-responses. A position statement by the American Society of Neurophysiological Monitoring. J Clin Monit Comput. 2005;19(6):437–61.
MacDonald DB, Dong C, Quatrale R, Sala F, Skinner S, Soto F, et al. Recommendations of the International Society of Intraoperative Neurophysiology for intraoperative somatosensory evoked potentials. Clin Neurophysiol. 2019;130(1):161–79.
Macdonald DB, Skinner S, Shils J, Yingling C. Intraoperative motor evoked potential monitoring—a position statement by the American Society of Neurophysiological Monitoring. Clin Neurophysiol. 2013;124(12):2291–316.
Monitoring the nervous system for anesthesiologists and other health care professionals. 2nd ed. Springer; 2011.
Schirmer CM, Shils JL, Arle JE, Cosgrove GR, Dempsey PK, Tarlov E, et al. Heuristic map of myotomal innervation in humans using direct intraoperative nerve root stimulation. J Neurosurg Spine. 2011;15(1):64–70.
Riley MR, Doan AT, Vogel RW, Aguirre AO, Pieri KS, Scheid EH. Use of motor evoked potentials during lateral lumbar interbody fusion reduces postoperative deficits. Spine J. 2018;18(10):1763–78.
Block J, Silverstein JW, Ball HT, Mermelstein LE, DeWal HS, Madhok R, et al. Motor evoked potentials for femoral nerve protection in transpsoas lateral access surgery of the spine. Neurodiagn J. 2015;55(1):36–45.
Alluri RK, Vaishnav AS, Sivaganesan A, Ricci L, Sheha E, Qureshi SA. Multimodality intraoperative neuromonitoring in lateral lumbar interbody fusion: a review of alerts in 628 patients. Global Spine J. 2021;21925682211000320.
Chaudhary K, Speights K, McGuire K, White AP. Trans-cranial motor evoked potential detection of femoral nerve injury in trans-psoas lateral lumbar interbody fusion. J Clin Monit Comput. 2015;29(5):549–54.
Silverstein JW, Block J, Smith ML, Bomback DA, Sanderson S, Paul J, et al. Femoral nerve neuromonitoring for lateral lumbar interbody fusion surgery. Spine J. 2021;22(2):296–304.
Yaylali I, Ju H, Yoo J, Ching A, Hart R. Intraoperative neurophysiological monitoring in anterior lumbar interbody fusion surgery. J Clin Neurophysiol. 2014;31(4):352–5.
Kaliya-Perumal A-K, Charng J-R, Niu C-C, Tsai T-T, Lai P-L, Chen L-H, et al. Intraoperative electromyographic monitoring to optimize safe lumbar pedicle screw placement—a retrospective analysis. BMC Musculoskelet Disord. 2017;18(1):229.
Troni W, Benech CA, Perez R, Tealdi S, Berardino M, Benech F. Focal hole versus screw stimulation to prevent false negative results in detecting pedicle breaches during spinal instrumentation. Clin Neurophysiol. 2019;130(4):573–81.
Raynor BL, Lenke LG, Bridwell KH, Taylor BA, Padberg AM. Correlation between low triggered electromyographic thresholds and lumbar pedicle screw malposition: analysis of 4857 screws. Spine (Phila Pa 1976). 2007;32(24):2673–8.
Donohue ML, Swaminathan V, Gilbert JL, Fox CW, Smale J, Moquin RR, et al. Intraoperative neuromonitoring: can the results of direct stimulation of titanium-alloy pedicle screws in the thoracic spine be trusted? J Clin Neurophysiol. 2012;29(6):502–8.
Melachuri SR, Melachuri MK, Mina A, Anetakis K, Crammond DJ, Balzer JR, et al. Optimal “low” pedicle screw stimulation threshold to predict new postoperative lower-extremity neurologic deficits during lumbar spinal fusions. World Neurosurg. 2021;151:e250–6.
Holland NR, Lukaczyk TA, Riley LH 3rd, Kostuik JP. Higher electrical stimulus intensities are required to activate chronically compressed nerve roots. Implications for intraoperative electromyographic pedicle screw testing. Spine (Phila Pa 1976). 1998;23(2):224–7.
Minahan RE, Riley LH 3rd, Lukaczyk T, Cohen DB, Kostuik JP. The effect of neuromuscular blockade on pedicle screw stimulation thresholds. Spine (Phila Pa 1976). 2000;25(19):2526–30.
Romstöck J, Strauss C, Fahlbusch R. Continuous electromyography monitoring of motor cranial nerves during cerebellopontine angle surgery. J Neurosurg. 2000;93(4):586–93.
Melachuri SR, Kaur J, Melachuri MK, Ninaci D, Crammond DJ, Balzer JR, et al. The diagnostic accuracy of somatosensory evoked potentials in evaluating neurological deficits during 1057 lumbar interbody fusions. J Clin Neurosci. 2019;61:78–83.
Hamilton DK, Smith JS, Sansur CA, Glassman SD, Ames CP, Berven SH, et al. Rates of new neurological deficit associated with spine surgery based on 108,419 procedures: a report of the scoliosis research society morbidity and mortality committee. Spine (Phila Pa 1976). 2011;36(15):1218–28.
Silverstein J, Mermelstein L, DeWal H, Basra S. Saphenous nerve somatosensory evoked potentials: a novel technique to monitor the femoral nerve during transpsoas lumbar lateral interbody fusion. Spine (Phila Pa 1976). 2014;39(15):1254–60.
Wilent WB, Tesdahl EA, Trott JT, Tassone S, Harrop JS, Klineberg EO, et al. Impact of inhalational anesthetic agents on the baseline monitorability of motor evoked potentials (MEPs) during spine surgery: a review of 22,755 cervical and lumbar procedures. Spine J. 2021;21(11):1839–46.
Gonzalez AA, Cheongsiatmoy J, Shilian P, Parikh P. Comparison of transcranial motor evoked potential amplitude responses between intramuscular and subcutaneous needles in proximal thigh muscle. J Clin Neurophysiol. 2018;35(5):431–5.
Tamkus A, Rice KS, Hoffman G. Transcranial motor evoked potential alarm criteria to predict foot drop injury during lumbosacral surgery. Spine (Phila Pa 1976). 2018;43(4):E227–33.
Sutter MA, Eggspuehler A, Grob D, Porchet F, Jeszenszky D, Dvorak J. Multimodal intraoperative monitoring (MIOM) during 409 lumbosacral surgical procedures in 409 patients. Eur Spine J. 2007;16(Suppl 2):S221–8.
Bhalodia VM, Schwartz DM, Sestokas AK, Bloomgarden G, Arkins T, Tomak P, et al. Efficacy of intraoperative monitoring of transcranial electrical stimulation-induced motor evoked potentials and spontaneous electromyography activity to identify acute-versus delayed-onset C-5 nerve root palsy during cervical spine surgery: clinical article. J Neurosurg Spine. 2013;19(4):395–402.
Wilent WB, Rhee JM, Harrop JS, Epplin-Zapf T, Bose M, Tesdahl EA, et al. Therapeutic impact of traction release after C5 nerve root motor evoked potential (MEP) alerts in cervical spine surgery. Clin Spine Surg. 2020;33(10):E442–7.
Wilent WB, Trott JM, Sestokas AK. Roadmap for motor evoked potential (MEP) monitoring for patients undergoing lumbar and lumbosacral spinal fusion procedures. Neurodiagn J. 2021;61(1):27–36.
Sloan TB, Toleikis JR, Toleikis SC, Koht A. Intraoperative neurophysiological monitoring during spine surgery with total intravenous anesthesia or balanced anesthesia with 3% desflurane. J Clin Monit Comput. 2015;29(1):77–85.
Mobbs RJ, Phan K, Malham G, Seex K, Rao PJ. Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF. J Spine Surg. 2015;1(1):2–18.
Wood KB, Devine J, Fischer D, Dettori JR, Janssen M. Vascular injury in elective anterior lumbosacral surgery. Spine (Phila Pa 1976). 2010;35(9 Suppl):S66–75.
Nair MN, Ramakrishna R, Slimp J, Kinney G, Chesnut RM. Left iliac artery injury during anterior lumbar spine surgery diagnosed by intraoperative neurophysiological monitoring. Eur Spine J. 2010;19(Suppl 2):S203–5.
Isley MR, Zhang X-F, Smith RC, Cohen MJ. Intraoperative neuromonitoring detects thrombotic occlusion of the left common iliac arterial bifurcation after anterior lumbar interbody fusion: case report. J Spinal Disord Tech. 2007;20(1):104–8.
Woods K, Fonseca A, Miller LE. Two-year outcomes from a single surgeon’s learning curve experience of oblique lateral interbody fusion without intraoperative neuromonitoring. Cureus. 2017;9(12):e1980.
Lee T-K, Kim J-Y, Han M-S, Lee J-K, Moon BJ. Neurologic deficit due to vertebral body osteophytes after oblique lumbar interbody fusion: a case report. Medicine (Baltimore). 2021;100(50):e28095.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Wilent, W.B., Trott, J., Epplin-Zapf, T., Sestokas, A.K. (2023). IONM During Lumbosacral Spinal Fusion Procedures. In: Seubert, C.N., Balzer, J.R. (eds) Koht, Sloan, Toleikis's Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals. Springer, Cham. https://doi.org/10.1007/978-3-031-09719-5_33
Download citation
DOI: https://doi.org/10.1007/978-3-031-09719-5_33
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-09718-8
Online ISBN: 978-3-031-09719-5
eBook Packages: MedicineMedicine (R0)