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Are Natural Products an Alternative Therapy for Dermatophytosis?

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Dermatophytes and Dermatophytoses

Abstract

Dermatophytosis is an important health concern with an increasing negative impact due to unsuccessful therapeutic approaches. Natural products have emerged as promising alternative/complementary agents, due to long traditional uses and increasing scientific recognition. Current knowledge on the antidermatophytic activity of natural products, mainly plant extracts with an up-to-date status on their activity, mechanism of action, developed pharmaceutical formulations, and effectiveness in animal models of infection and patients with dermatophytosis is presented. Although the information available on this matter points out an undeniable potential of these compounds, their usage by the pharmaceutical industry and medical community remains a challenge.

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Authors and Affiliations

  1. Faculty of Medicine, University of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Health Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal

    Mónica Zuzarte

  2. University of Coimbra, Center for Innovative Biomedicine and Biotechnology (CIBB), Health Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal

    Mónica Zuzarte

  3. Clinical Academic Centre of Coimbra (CACC), Coimbra, Portugal

    Mónica Zuzarte

  4. CIIMAR, Interdisciplinary Centre of Marine and Environmental Research of the University of Porto, Terminal de Cruzeiros do Porto de Leixões, Matosinhos, Portugal

    Graciliana Lopes & Eugénia Pinto

  5. Department of Biology, FCUP, Faculty of Sciences, University of Porto, Rua do Campo Alegre, Porto, Portugal

    Graciliana Lopes

  6. Microbiology Service, Biological Sciences Department, Faculty of Pharmacy, University of Porto, Porto, Portugal

    Eugénia Pinto

  7. Chemical Engineering Department of FCTUC, Chemical Process Engineering and Forest Products Research Centre (CIEPQPF), Rua Sílvio Lima, Coimbra, Portugal

    Lígia Salgueiro

  8. Faculty of Pharmacy, University of Coimbra, Health Sciences Campus, Azinhaga de Santa Comba, Coimbra, Portugal

    Lígia Salgueiro

Authors
  1. Mónica Zuzarte
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  2. Graciliana Lopes
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  3. Eugénia Pinto
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  4. Lígia Salgueiro
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Corresponding author

Correspondence to Eugénia Pinto .

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Editors and Affiliations

  1. Univ Angers, Université de Bretagne Occidentale, CHU, SFR ICAT, Groupe d’Etude des Interactions Hôte-Pathogène (GEIHP, EA 3142), Angers, France

    Jean-Philippe Bouchara

  2. Laboratory for Medical Microbiology, Rötha, Sachsen, Germany

    Pietro Nenoff

  3. Mediprobe Research Inc., London, ON, Canada

    Aditya K. Gupta

  4. New York State Department of Health Wadsworth Center, Mycology Laboratory, Albany, NY, USA

    Vishnu Chaturvedi

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Zuzarte, M., Lopes, G., Pinto, E., Salgueiro, L. (2021). Are Natural Products an Alternative Therapy for Dermatophytosis?. In: Bouchara, JP., Nenoff, P., Gupta, A.K., Chaturvedi, V. (eds) Dermatophytes and Dermatophytoses. Springer, Cham. https://doi.org/10.1007/978-3-030-67421-2_22

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