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Nutraceuticals and Cardiovascular Disease

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Nutraceuticals and Cardiovascular Disease

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Cardiovascular disease (CVD) remains the primary cause of mortality worldwide, taking an estimated 17.9 million lives each year. Among several cardiometabolic risk factors, dyslipidemia, and especially high low-density lipoprotein cholesterol (LDL-C) levels, are associated with the development and progression of atherosclerosis and its clinical sequelae. Recent studies have shown promising results for nutraceutical compounds on various CVD risk factors and complications. In addition to looking at individual nutrients or foods, dietary pattern have also emerged as a complementary approach to examine the relationship between the overall diet and the risk for CVD. The Mediterranean Diet (MedDiet) seems to provide the best dietary tools to improve cardiovascular health, although further large-scale randomized clinical trials are necessary to confirm this. In this chapter, we will discuss currently available data about the effects of nutraceuticals and some foods on different cardiometabolic risk factors and overall CVD risk. In addition, a brief discussion is provided on the role of MedDiet, including the international guidelines which support its use in prevention and/or treatment of subjects at CVD risk.

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Authors and Affiliations

  1. PROMISE Department, School of Medicine, University of Palermo, Palermo, Italy

    Roberta Chianetta, Alexandros Sachinidis, Dragana Nikolic, Luca Marco Luzzu & Manfredi Rizzo

  2. 2nd Propaedeutics Department of Internal Medicine, Hippocration Hospital, Medical School of Aristotle University Thessaloniki, Thessaloniki, Greece

    Alexandros Sachinidis

  3. Department of Diabetes, Nutrition and Metabolic Diseases, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

    Anca Pantea Stoian

  4. Department of Preventive Cardiology, CGH Medical Center, Sterling, IL, USA

    Peter P. Toth

  5. Cicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Peter P. Toth

  6. Italian Nutraceutical Society (SINut), Bologna, Italy

    Manfredi Rizzo

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  1. Roberta Chianetta
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  1. S. Orsola-Malpighi University Hospital, University of Bologna, BOLOGNA, Bologna, Italy

    Arrigo F.G. Cicero

  2. School of Medicine, University of Palermo, Palermo, Palermo, Italy

    Manfredi Rizzo

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Chianetta, R. et al. (2021). Nutraceuticals and Cardiovascular Disease. In: Cicero, A.F., Rizzo, M. (eds) Nutraceuticals and Cardiovascular Disease. Contemporary Cardiology. Humana, Cham. https://doi.org/10.1007/978-3-030-62632-7_5

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