Abstract
This chapter highlights the advantages, limitations and pitfalls of functional imaging with Fluorodeoxy-Glucose Positron Emission Computed Tomography (FDG PET CT) and compares its diagnostic performance with structural imaging modalities Computer Tomography (CT) and Magnetic Resonance Imaging (MRI) in the management of patients with pancreatic cancer.
Structural imaging in the diagnosis of pancreatic malignancy and tumour recurrence is a radiological challenge, in particularly treatment induced changes are difficult to interpret and can mask local recurrence. FDG PET CT can overcome some of the problems encountered in structural imaging and provides added value in the diagnosis and management of pancreatic cancer. The indications for FDG PET CT include tumour staging, evaluating tumour recurrence, monitoring response to therapy and targeted biopsy planning in patients with clinically suspected pancreatic cancer and equivocal structural imaging features or non-diagnostic fine-needle aspiration findings. FDG-PET can be cost beneficial and prevent unnecessary surgical procedures by detecting distant metastases not identified on CT or MRI.
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Wieshmann, H., Desai, K.N.P. (2021). PET in Pancreatic Cancer. In: Søreide, K., Stättner, S. (eds) Textbook of Pancreatic Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-53786-9_36
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