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Surgical Care

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Geriatric Medicine

Abstract

Older adults, those who are 65 years and older, are a growing segment of the population, expected to nearly double by 2050. Based on these projections, an increasing number of older adults will require wide-ranging surgical services. Indeed, half of persons 65 years and older will require surgery over their lifetime. Despite the substantial and increasing number of older adults undergoing surgical procedures, standard perioperative care lacks a person-centered approach that is needed for the management of a complex population.

Surgical care in older adults is unique due to the effects of aging physiology, multimorbidity, and baseline cognitive and functional impairments. Older adults are more likely to develop postoperative complications, including cardiovascular events, functional and cognitive decline, loss of independence, and mortality. However, there is growing evidence that improved outcomes can be obtained with organized evidence-based programs, such as orthogeriatric fracture services.

This chapter will provide a framework for surgeons, anesthesiologists, and medical professionals to deliver evidence-based, comprehensive, and person-centered care that integrates geriatric principles into surgical care for older adults. The chapter will utilize the Age-Friendly Health System 4Ms principles to frame pre- and postoperative care; provide guidance for anesthesia and intraoperative management in older adults; discuss the two most common elective surgical procedures in older adults, namely, total hip and total knee replacements; and describe the medical management of hip fracture.

As the number of surgeries performed worldwide approaches 250 million per year, providing high-quality surgical care is imperative to avoid significant morbidity and mortality in this population.

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References

  1. Werner, C. A. (2011). The Older Population:2010. 19.

    Google Scholar 

  2. Dall TM, Gallo PD, Chakrabarti R, West T, Semilla AP, Storm MV. An aging population and growing disease burden will require a large and specialized health care workforce by 2025. Health Aff (Project Hope). 2013;32(11):2013–20. https://doi.org/10.1377/hlthaff.2013.0714.

    Article  Google Scholar 

  3. Kim S, Han H-S, Jung H, Kim K, Hwang DW, Kang S-B, Kim C-H. Multidimensional frailty score for the prediction of postoperative mortality risk. JAMA Surg. 2014;149(7):633–40. https://doi.org/10.1001/jamasurg.2014.241.

    Article  PubMed  Google Scholar 

  4. Mohanty S, Rosenthal RA, Russell MM, Neuman MD, Ko CY, Esnaola NF. Optimal Perioperative Management of the Geriatric Patient: A Best Practices Guideline from the American College of Surgeons NSQIP and the American Geriatrics Society. J Am Coll Surg. 2016;222(5):930–47. https://doi.org/10.1016/j.jamcollsurg.2015.12.026.

    Article  PubMed  Google Scholar 

  5. Bell RH, Drach GW, Rosenthal RA. Proposed competencies in geriatric patient care for use in assessment for initial and continued board certification of surgical specialists. J Am Coll Surg. 2011;213(5):683–90. https://doi.org/10.1016/j.jamcollsurg.2011.08.004.

    Article  PubMed  Google Scholar 

  6. Chow WB, Rosenthal RA, Merkow RP, Ko CY, Esnaola NF, American College of Surgeons National Surgical Quality Improvement Program, & American Geriatrics Society. Optimal preoperative assessment of the geriatric surgical patient: A best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg. 2012;215(4):453–66. https://doi.org/10.1016/j.jamcollsurg.2012.06.017.

    Article  PubMed  Google Scholar 

  7. McGory ML, Kao KK, Shekelle PG, Rubenstein LZ, Leonardi MJ, Parikh JA, Fink A, Ko CY. Developing quality indicators for elderly surgical patients. Ann Surg. 2009;250(2):338–47. https://doi.org/10.1097/SLA.0b013e3181ae575a.

    Article  PubMed  Google Scholar 

  8. Wolfe JD, Wolfe NK, Rich MW. Perioperative care of the geriatric patient for noncardiac surgery. Clin Cardiol. 2020;43(2):127–36. https://doi.org/10.1002/clc.23302.

    Article  PubMed  Google Scholar 

  9. Cullen KA, Hall MJ, Golosinskiy A. Ambulatory surgery in the United States, 2006. Natl Health Stat Rep. 2009;11:1–25.

    Google Scholar 

  10. Deiner S, Westlake B, Dutton RP. Patterns of surgical care and complications in elderly adults. J Am Geriatr Soc. 2014;62(5):829–35. https://doi.org/10.1111/jgs.12794.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Hall MJ, DeFrances CJ, Williams SN, Golosinskiy A, Schwartzman A. National Hospital Discharge Survey: 2007 summary. Natl Health Stat Rep. 2010;29(1–20):24.

    Google Scholar 

  12. Monk TG, Saini V, Weldon BC, Sigl JC. Anesthetic management and one-year mortality after noncardiac surgery. Anesth Analg. 2005;100(1):4–10. https://doi.org/10.1213/01.ANE.0000147519.82841.5E.

    Article  PubMed  Google Scholar 

  13. Turrentine FE, Wang H, Simpson VB, Jones RS. Surgical risk factors, morbidity, and mortality in elderly patients. J Am Coll Surg. 2006;203(6):865–77. https://doi.org/10.1016/j.jamcollsurg.2006.08.026.

    Article  PubMed  Google Scholar 

  14. Nordquist D, Halaszynski TM. Perioperative multimodal anesthesia using regional techniques in the aging surgical patient. Pain Res Treat. 2014;2014(902):174. https://doi.org/10.1155/2014/902174.

    Article  Google Scholar 

  15. Mangano DT. Perioperative cardiac morbidity. Anesthesiology. 1990;72(1):153–84. https://doi.org/10.1097/00000542-199001000-00025.

    Article  CAS  PubMed  Google Scholar 

  16. Mangano DT, Browner WS, Hollenberg M, Li J, Tateo IM. Long-term cardiac prognosis following noncardiac surgery. The Study of Perioperative Ischemia Research Group. JAMA. 1992;268(2):233–9. https://doi.org/10.1001/jama.268.2.233.

    Article  CAS  PubMed  Google Scholar 

  17. Janssens JP, Pache JC, Nicod LP. Physiological changes in respiratory function associated with ageing. Eur Respir J. 1999;13(1):197–205. https://doi.org/10.1034/j.1399-3003.1999.13a36.x.

    Article  CAS  PubMed  Google Scholar 

  18. Sharma G, Goodwin J. Effect of aging on respiratory system physiology and immunology. Clin Interv Aging. 2006;1(3):253–60.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Peters R. Ageing and the brain. Postgrad Med J. 2006;82(964):84–8. https://doi.org/10.1136/pgmj.2005.036665.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Wyss-Coray T. Ageing, neurodegeneration and brain rejuvenation. Nature. 2016;539(7628):180–6. https://doi.org/10.1038/nature20411.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Salive ME. Multimorbidity in older adults. Epidemiol Rev. 2013;35:75–83. https://doi.org/10.1093/epirev/mxs009.

    Article  PubMed  Google Scholar 

  22. Quiñones AR, Markwardt S, Botoseneanu A. Multimorbidity Combinations and Disability in Older Adults. J Gerontol A Biol Sci Med Sci. 2016;71(6):823–30. https://doi.org/10.1093/gerona/glw035.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Sorace J, Wong H-H, Worrall C, Kelman J, Saneinejad S, MaCurdy T. The complexity of disease combinations in the Medicare population. Popul Health Manag. 2011;14(4):161–6. https://doi.org/10.1089/pop.2010.0044.

    Article  PubMed  Google Scholar 

  24. Tinetti ME, Fried TR, Boyd CM. Designing Health Care for the Most Common Chronic Condition—Multimorbidity. JAMA. 2012;307(23):2493–4. https://doi.org/10.1001/jama.2012.5265.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Stabenau HF, Becher RD, Gahbauer EA, Leo-Summers L, Allore HG, Gill TM. Functional Trajectories Before and After Major Surgery in Older Adults. Ann Surg. 2018;268(6):911–7. https://doi.org/10.1097/SLA.0000000000002659.

    Article  PubMed  Google Scholar 

  26. Mashour GA, Woodrum DT, Avidan MS. Neurological complications of surgery and anaesthesia. Br J Anaesth. 2015;114(2):194–203. https://doi.org/10.1093/bja/aeu296.

    Article  CAS  PubMed  Google Scholar 

  27. Robinson TN, Wu DS, Sauaia A, Dunn CL, Stevens-Lapsley JE, Moss M, Stiegmann GV, Gajdos C, Cleveland JC, Inouye SK. Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties. Ann Surg. 2013;258(4):582–588; discussion 588–590. https://doi.org/10.1097/SLA.0b013e3182a4e96c.

    Article  Google Scholar 

  28. Mosquera C, Spaniolas K, Fitzgerald TL. Impact of frailty on surgical outcomes: The right patient for the right procedure. Surgery. 2016;160(2):272–80. https://doi.org/10.1016/j.surg.2016.04.030.

    Article  PubMed  Google Scholar 

  29. Odden MC, Peralta CA, Haan MN, Covinsky KE. Rethinking the Association of High Blood Pressure with Mortality in Elderly Adults: The Impact of Frailty. Arch Intern Med. 2012;172(15):1162–8. https://doi.org/10.1001/archinternmed.2012.2555.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Blauth, M., Kates, S. L., & Nicolas, J. (2018). Osteoporotic Fracture Care. AOTrauma.

    Google Scholar 

  31. Holland R. Anaesthetic mortality in New South Wales. Br J Anaesth. 1987;59(7):834–41. https://doi.org/10.1093/bja/59.7.834.

    Article  CAS  PubMed  Google Scholar 

  32. Fisher AA, Davis MW, Rubenach SE, Sivakumaran S, Smith PN, Budge MM. Outcomes for older patients with hip fractures: The impact of orthopedic and geriatric medicine cocare. J Orthop Trauma. 2006;20(3):172–178; discussion 179–180. https://doi.org/10.1097/01.bot.0000202220.88855.16.

    Article  Google Scholar 

  33. Folbert ECE, Smit RS, van der Velde D, Regtuijt EMM, Klaren MH, Hegeman JHH. Geriatric fracture center: A multidisciplinary treatment approach for older patients with a hip fracture improved quality of clinical care and short-term treatment outcomes. Geriatr Orthop Surg Rehabil. 2012;3(2):59–67. https://doi.org/10.1177/2151458512444288.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Friedman SM, Mendelson DA, Bingham KW, Kates SL. Impact of a comanaged Geriatric Fracture Center on short-term hip fracture outcomes. Arch Intern Med. 2009;169(18):1712–7. https://doi.org/10.1001/archinternmed.2009.321.

    Article  PubMed  Google Scholar 

  35. Nicholas JA. Preoperative optimization and risk assessment. Clin Geriatr Med. 2014;30(2):207–18. https://doi.org/10.1016/j.cger.2014.01.003.

    Article  PubMed  Google Scholar 

  36. Semel J, Gray JM, Ahn HJ, Nasr H, Chen JJ. Predictors of outcome following hip fracture rehabilitation. PM & R: J Inj Funct Rehabi. 2010;2(9):799–805. https://doi.org/10.1016/j.pmrj.2010.04.019.

    Article  Google Scholar 

  37. Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, Davila-Roman VG, Gerhard-Herman MD, Holly TA, Kane GC, Marine JE, Nelson MT, Spencer CC, Thompson A, Ting HH, Uretsky BF, Wijeysundera DN, American College of Cardiology, & American Heart Association. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. J Am Coll Cardiol. 2014;64(22):e77–137. https://doi.org/10.1016/j.jacc.2014.07.944.

    Article  PubMed  Google Scholar 

  38. Seitz DP, Adunuri N, Gill SS, Rochon PA. Prevalence of dementia and cognitive impairment among older adults with hip fractures. J Am Med Dir Assoc. 2011;12(8):556–64. https://doi.org/10.1016/j.jamda.2010.12.001.

    Article  PubMed  Google Scholar 

  39. Viramontes O, Luan Erfe BM, Erfe JM, Brovman EY, Boehme J, Bader AM, Urman RD. Cognitive impairment and postoperative outcomes in patients undergoing primary total hip arthroplasty: A systematic review. J Clin Anesth. 2019;56:65–76. https://doi.org/10.1016/j.jclinane.2019.01.024.

    Article  PubMed  Google Scholar 

  40. Cockrell, J. R., & Folstein, M. F. (2002). Mini-mental state examination. Principles and practice of geriatric psychiatry. , 140–141.

    Google Scholar 

  41. Borson S, Scanlan JM, Chen P, Ganguli M. The Mini-Cog as a screen for dementia: Validation in a population-based sample. J Am Geriatr Soc. 2003;51(10):1451–4. https://doi.org/10.1046/j.1532-5415.2003.51465.x.

    Article  PubMed  Google Scholar 

  42. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005 Apr;53(4):695–9.

    Article  PubMed  Google Scholar 

  43. Tariq SH, Tumosa N, Chibnall JT, Perry HM III, Morley JE. The Saint Louis University Mental Status (SLUMS) Examination for detecting mild cognitive impairment and dementia is more sensitive than the Mini-Mental Status Examination (MMSE)-A pilot study. Am J Geriatr Psychiatr. 2006;14(11):900–10.

    Article  Google Scholar 

  44. Kroenke K, Spitzer RL, Williams JB, Löwe B. An ultra-brief screening scale for anxiety and depression: the PHQ–4. Psychosomatics. 2009;50(6):613–21.

    PubMed  Google Scholar 

  45. Parmelee PA, Katz IR. Geriatric depression scale. J Am Geriatr Soc. 1990;38(12):1379.

    Article  CAS  PubMed  Google Scholar 

  46. Parker MJ, Palmer CR. A new mobility score for predicting mortality after hip fracture. J Bone Joint Surg Bri Vol. 1993;75(5):797–8.

    Article  CAS  Google Scholar 

  47. Abel RB, Rosenblatt MA. Preoperative evaluation and preparation of patients for orthopedic surgery. Anesthesiol Clin. 2014;32(4):881–92. https://doi.org/10.1016/j.anclin.2014.08.007.

    Article  PubMed  Google Scholar 

  48. Jetté M, Sidney K, Blümchen G. Metabolic equivalents (METS) in exercise testing, exercise prescription, and evaluation of functional capacity. Clin Cardiol. 1990;13(8):555–65. https://doi.org/10.1002/clc.4960130809.

    Article  PubMed  Google Scholar 

  49. Panayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, Orgill DP, Neppl RL, Javedan H, Bhasin S, Sinha I. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2019;218(2):393–400. https://doi.org/10.1016/j.amjsurg.2018.11.020.

    Article  CAS  PubMed  Google Scholar 

  50. Schmucker AM, Hupert N, Mandl LA. The Impact of Frailty on Short-Term Outcomes After Elective Hip and Knee Arthroplasty in Older Adults: A Systematic Review. Geriatr Orthop Surg Rehabil. 2019;10 https://doi.org/10.1177/2151459319835109.

  51. Gillick M. Guest Editorial: Pinning Down Frailty. J Gerontol Series A. 2001;56(3):M134–5. https://doi.org/10.1093/gerona/56.3.M134.

    Article  CAS  Google Scholar 

  52. Li S, Zhang J, Zheng H, Wang X, Liu Z, Sun T. Prognostic Role of Serum Albumin, Total Lymphocyte Count, and Mini Nutritional Assessment on Outcomes After Geriatric Hip Fracture Surgery: A Meta-Analysis and Systematic Review. J Arthroplast. 2019;34(6):1287–96. https://doi.org/10.1016/j.arth.2019.02.003.

    Article  Google Scholar 

  53. Heger P, Probst P, Wiskemann J, Steindorf K, Diener MK, Mihaljevic AL. A Systematic Review and Meta-analysis of Physical Exercise Prehabilitation in Major Abdominal Surgery (PROSPERO 2017 CRD42017080366). J Gastrointest Surg. 2020;24(6):1375–85. https://doi.org/10.1007/s11605-019-04287-w.

    Article  PubMed  Google Scholar 

  54. Kamarajah SK, Bundred J, Weblin J, Tan BHL. Critical appraisal on the impact of preoperative rehabilitation and outcomes after major abdominal and cardiothoracic surgery: A systematic review and meta-analysis. Surgery. 2020;167(3):540–9. https://doi.org/10.1016/j.surg.2019.07.032.

    Article  PubMed  Google Scholar 

  55. Thomas G, Tahir MR, Bongers BC, Kallen VL, Slooter GD, van Meeteren NL. Prehabilitation before major intra-abdominal cancer surgery: A systematic review of randomised controlled trials. Eur J Anaesthesiol. 2019;36(12):933–45. https://doi.org/10.1097/EJA.0000000000001030.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Arora P, Rajagopalam S, Ranjan R, Kolli H, Singh M, Venuto R, Lohr J. Preoperative Use of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Is Associated with Increased Risk for Acute Kidney Injury after Cardiovascular Surgery. Clin J Am Soc Nephrol. 2008;3(5):1266–73. https://doi.org/10.2215/CJN.05271107.

    Article  PubMed  PubMed Central  Google Scholar 

  57. Cittanova ML, Zubicki A, Savu C, Montalvan C, Nefaa N, Zaier K, Riou B, Coriat P. The chronic inhibition of angiotensin-converting enzyme impairs postoperative renal function. Anesth Analg. 2001;93(5):1111–5. https://doi.org/10.1097/00000539-200111000-00008.

    Article  CAS  PubMed  Google Scholar 

  58. Onuigbo MAC. Reno-prevention vs. reno-protection: A critical re-appraisal of the evidence-base from the large RAAS blockade trials after ONTARGET--a call for more circumspection. QJM. 2009;102(3):155–67. https://doi.org/10.1093/qjmed/hcn142.

    Article  CAS  PubMed  Google Scholar 

  59. Kheterpal S, Khodaparast O, Shanks A, O’Reilly M, Tremper KK. Chronic angiotensin-converting enzyme inhibitor or angiotensin receptor blocker therapy combined with diuretic therapy is associated with increased episodes of hypotension in noncardiac surgery. J Cardiothorac Vasc Anesth. 2008;22(2):180–6. https://doi.org/10.1053/j.jvca.2007.12.020.

    Article  CAS  PubMed  Google Scholar 

  60. Biccard BM, Sear JW, Foëx P. Statin therapy: A potentially useful peri-operative intervention in patients with cardiovascular disease. Anaesthesia. 2005;60(11):1106–14. https://doi.org/10.1111/j.1365-2044.2005.04405.x.

    Article  CAS  PubMed  Google Scholar 

  61. Poldermans D, Bax JJ, Boersma E, De Hert S, Eeckhout E, Fowkes G, Gorenek B, Hennerici MG, Iung B, Kelm M, Kjeldsen KP, Kristensen SD, Lopez-Sendon J, Pelosi P, Philippe F, Pierard L, Ponikowski P, Schmid J-P, Sellevold OF, et al. Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: The Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA). Eur J Anaesthesiol. 2010;27(2):92–137. https://doi.org/10.1097/EJA.0b013e328334c017.

    Article  PubMed  Google Scholar 

  62. Douketis JD, Spyropoulos AC, Spencer FA, Mayr M, Jaffer AK, Eckman MH, Dunn AS, Kunz R. Perioperative management of antithrombotic therapy: Antithrombotic Therapy and Prevention of Thrombosis, ninth ed.: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141(2 Suppl):e326S–50S. https://doi.org/10.1378/chest.11-2298.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: Results from the National Registry of Atrial Fibrillation. JAMA. 2001;285(22):2864–70. https://doi.org/10.1001/jama.285.22.2864.

    Article  CAS  PubMed  Google Scholar 

  64. Lip GYH, Nieuwlaat R, Pisters R, Lane DA, Crijns HJGM. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The euro heart survey on atrial fibrillation. Chest. 2010;137(2):263–72. https://doi.org/10.1378/chest.09-1584.

    Article  PubMed  Google Scholar 

  65. Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, Nelson ME, Wells PS, Gould MK, Dentali F, Crowther M, Kahn SR. Antithrombotic Therapy for VTE Disease. Chest. 2012;141(2 Suppl):e419S–94S. https://doi.org/10.1378/chest.11-2301.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  66. Pisters R, Lane DA, Nieuwlaat R, De Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093–100.

    Article  PubMed  Google Scholar 

  67. Caprini JA, Arcelus JI, Hasty JH, Tamhane AC, Fabrega F. Clinical assessment of venous thromboembolic risk in surgical patients. Semin Thromb Hemost. 1991;17(Suppl 3):304–12.

    PubMed  Google Scholar 

  68. American College of Surgeons. Statement on Advance Directives by Patients: “Do Not Resuscitate” in the Operating Room. Bull Am Coll Surg. 2014; https://www.facs.org/about-acs/statements/19-advance-directives

    Google Scholar 

  69. Monahan RH. Editorial: Joint Commission on Allied Health Personnel in Ophthalmology. Arch Ophthalmol. 1975;93(7):471. https://doi.org/10.1001/archopht.1975.01010020487001.

    Article  CAS  PubMed  Google Scholar 

  70. Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis. 1987;40(5):373–83. https://doi.org/10.1016/0021-9681(87)90171-8.

    Article  CAS  PubMed  Google Scholar 

  71. Lee SJ, Go AS, Lindquist K, Bertenthal D, Covinsky KE. Chronic Conditions and Mortality Among the Oldest Old. Am J Public Health. 2008;98(7):1209–14. https://doi.org/10.2105/AJPH.2007.130955.

    Article  PubMed  PubMed Central  Google Scholar 

  72. Yourman LC, Lee SJ, Schonberg MA, Widera EW, Smith AK. Prognostic indices for older adults: A systematic review. JAMA. 2012;307(2):182–92. https://doi.org/10.1001/jama.2011.1966.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  73. Lee, S., ., & et al. (2015). Information about ePrognosis—Estimating Prognosis for Elders. https://eprognosis.ucsf.edu/information.php

  74. Boyd C, Smith CD, Masoudi FA, Blaum CS, Dodson JA, Green AR, Kelley A, Matlock D, Ouellet J, Rich MW, Schoenborn NL, Tinetti ME. Decision Making for Older Adults With Multiple Chronic Conditions: Executive Summary for the American Geriatrics Society Guiding Principles on the Care of Older Adults With Multimorbidity. J Am Geriatr Soc. 2019;67(4):665–73. https://doi.org/10.1111/jgs.15809.

    Article  PubMed  Google Scholar 

  75. Shiga T, Wajima Z, Ohe Y. Is operative delay associated with increased mortality of hip fracture patients? Systematic review, meta-analysis, and meta-regression. Canadian J Anaesth. 2008;55(3):146–54. https://doi.org/10.1007/BF03016088.

    Article  Google Scholar 

  76. Lee Thomas H, Marcantonio Edward R, Mangione Carol M, Thomas Eric J, Polanczyk Carisi A, Francis CE, Sugarbaker David J, Donaldson Magruder C, Robert P, Ho Kalon KL, Ludwig Lynn E, Pedan A, Goldman L. Derivation and Prospective Validation of a Simple Index for Prediction of Cardiac Risk of Major Noncardiac Surgery. Circulation. 1999;100(10):1043–9. https://doi.org/10.1161/01.CIR.100.10.1043.

    Article  Google Scholar 

  77. Bilimoria KY, Liu Y, Paruch JL, Zhou L, Kmiecik TE, Ko CY, Cohen ME. Development and evaluation of the universal ACS NSQIP surgical risk calculator: A decision aid and informed consent tool for patients and surgeons. J Am Coll Surg. 2013;217(5):833–42.e1–3. https://doi.org/10.1016/j.jamcollsurg.2013.07.385.

    Article  PubMed  PubMed Central  Google Scholar 

  78. Gupta PK, Gupta H, Sundaram A, Kaushik M, Fang X, Miller WJ, Esterbrooks DJ, Hunter CB, Pipinos II, Johanning JM, Lynch TG, Forse RA, Mohiuddin SM, Mooss AN. Development and validation of a risk calculator for prediction of cardiac risk after surgery. Circulation. 2011;124(4):381–7. https://doi.org/10.1161/CIRCULATIONAHA.110.015701.

    Article  PubMed  Google Scholar 

  79. Maxwell M, Moran CG, Moppett IK. Development and validation of a preoperative scoring system to predict 30 day mortality in patients undergoing hip fracture surgery. Br J Anaesth. 2008;101(4):511–7. https://doi.org/10.1093/bja/aen236.

    Article  CAS  PubMed  Google Scholar 

  80. Qaseem A, Snow V, Fitterman N, Hornbake ER, Lawrence VA, Smetana GW, Weiss K, Owens DK, Aronson M, Barry P, Casey DE, Cross JT, Fitterman N, Sherif KD, Weiss KB, Clinical Efficacy Assessment Subcommittee of the American College of Physicians. Risk assessment for and strategies to reduce perioperative pulmonary complications for patients undergoing noncardiothoracic surgery: A guideline from the American College of Physicians. Ann Intern Med. 2006;144(8):575–80. https://doi.org/10.7326/0003-4819-144-8-200604180-00008.

    Article  PubMed  Google Scholar 

  81. Onuoha OC, Arkoosh VA, Fleisher LA. Choosing wisely in anesthesiology: The gap between evidence and practice. JAMA Intern Med. 2014;174(8):1391–5. https://doi.org/10.1001/jamainternmed.2014.2309.

    Article  PubMed  Google Scholar 

  82. Friedman SM, Mendelson DA, Kates SL, McCann RM. Geriatric co-management of proximal femur fractures: Total quality management and protocol-driven care result in better outcomes for a frail patient population. J Am Geriatr Soc. 2008;56(7):1349–56. https://doi.org/10.1111/j.1532-5415.2008.01770.x.

    Article  PubMed  Google Scholar 

  83. American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart Association, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, American College of Chest Physicians, Douglas PS, Garcia MJ, Haines DE, Lai WW, Manning WJ, Patel AR, Picard MH, Polk DM, et al. ACCF/ASE/AHA/ASNC/HFSA/HRS/SCAI/SCCM/SCCT/SCMR 2011 Appropriate Use Criteria for Echocardiography. A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart Association, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance American College of Chest Physicians. J Am Soc Echocardio. 2011;24(3):229–67. https://doi.org/10.1016/j.echo.2010.12.008.

    Article  Google Scholar 

  84. Sinvani L, Mendelson DA, Sharma A, Nouryan CN, Fishbein JS, Qiu MG, Zeltser R, Makaryus AN, Wolf-Klein GP. Preoperative Noninvasive Cardiac Testing in Older Adults with Hip Fracture: A Multi-Site Study. J Am Geriatr Soc. 2020 Aug;68(8):1690–7.

    Article  PubMed  Google Scholar 

  85. Friedman SM, Mendelson DA. Epidemiology of fragility fractures. Clin Geriatr Med. 2014;30(2):175–81. https://doi.org/10.1016/j.cger.2014.01.001.

    Article  PubMed  Google Scholar 

  86. Sinvani L, Goldin M, Roofeh R, Idriss N, Goldman A, Klein Z, Mendelson DA, Carney MT. Implementation of Hip Fracture Co-Management Program (AGS CoCare: Ortho®) in a Large Health System. J Am Geriatr Soc. 2020; https://doi.org/10.1111/jgs.16483.

  87. Inouye SK. Delirium in Older Persons. N Engl J Med. 2006;354(11):1157–65. https://doi.org/10.1056/NEJMra052321.

    Article  CAS  PubMed  Google Scholar 

  88. Inouye SK. The dilemma of delirium: Clinical and research controversies regarding diagnosis and evaluation of delirium in hospitalized elderly medical patients. Am J Med. 1994;97(3):278–88. https://doi.org/10.1016/0002-9343(94)90011-6.

    Article  CAS  PubMed  Google Scholar 

  89. Inouye SK, Westendorp RGJ, Saczynski JS. Delirium in elderly people. Lancet. 2014;383(9920):911–22. https://doi.org/10.1016/S0140-6736(13)60688-1.

    Article  PubMed  Google Scholar 

  90. Leslie DL, Marcantonio ER, Zhang Y, Leo-Summers L, Inouye SK. One-year health care costs associated with delirium in the elderly population. Arch Intern Med. 2008;168(1):27–32. https://doi.org/10.1001/archinternmed.2007.4.

    Article  PubMed  PubMed Central  Google Scholar 

  91. National Clinical Guideline Centre (UK). Delirium: Diagnosis, Prevention and Management. Royal College of Physicians (UK); 2010. http://www.ncbi.nlm.nih.gov/books/NBK65558/

    Google Scholar 

  92. Witlox J, Eurelings LSM, de Jonghe JFM, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of postdischarge mortality, institutionalization, and dementia: A meta-analysis. JAMA. 2010;304(4):443–51. https://doi.org/10.1001/jama.2010.1013.

    Article  CAS  PubMed  Google Scholar 

  93. Sánchez A, Thomas C, Deeken F, Wagner S, Klöppel S, Kentischer F, von Arnim CAF, Denkinger M, Conzelmann LO, Biermann-Stallwitz J, Joos S, Sturm H, Metz B, Auer R, Skrobik Y, Eschweiler GW, Rapp MA, PAWEL Study group. Patient safety, cost-effectiveness, and quality of life: Reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults-study protocol for a stepped-wedge cluster randomized trial (PAWEL Study). Trials. 2019;20(1):71. https://doi.org/10.1186/s13063-018-3148-8.

    Article  PubMed  PubMed Central  Google Scholar 

  94. Inouye SK, Bogardus ST Jr, Baker DI, Leo-Summers L, Cooney LM Jr. The Hospital Elder Life Program: a model of care to prevent cognitive and functional decline in older hospitalized patients. Hospital Elder Life Program. J Am Geriatr Soc. 2000;48(12):1697–706.

    Article  CAS  PubMed  Google Scholar 

  95. Inouye SK, Robinson T, Blaum C, Busby-Whitehead J, Boustani M, Chalian A, Deiner S, Fick D, Hutchison L, Johanning J, Katlic M. Postoperative delirium in older adults: best practice statement from the American Geriatrics Society. J Am Coll Surg. 2015;220(2):136–48e1.

    Article  Google Scholar 

  96. American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674–94. https://doi.org/10.1111/jgs.15767.

    Article  Google Scholar 

  97. Janssen T, Alberts A, Hooft L, Mattace-Raso F, Mosk C, van der Laan L. Prevention of postoperative delirium in elderly patients planned for elective surgery: Systematic review and meta-analysis. Clin Interv Aging. 2019;14:1095–117. https://doi.org/10.2147/CIA.S201323.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  98. Oh ES, Needham DM, Nikooie R, Wilson LM, Zhang A, Robinson KA, Neufeld KJ. Antipsychotics for preventing delirium in hospitalized adults: A systematic review. Ann Intern Med. 2019;171(7):474–84. https://doi.org/10.7326/M19-1859.

    Article  PubMed  Google Scholar 

  99. Pan H, Liu C, Ma X, Xu Y, Zhang M, Wang Y. Perioperative dexmedetomidine reduces delirium in elderly patients after non-cardiac surgery: A systematic review and meta-analysis of randomized-controlled trials. Canadian J Anaesth. 2019;66(12):1489–500. https://doi.org/10.1007/s12630-019-01440-6.

    Article  Google Scholar 

  100. Peng K, Ji F-H, Liu H-Y, Zhang J, Chen Q-C, Jiang Y-H. Effects of perioperative dexmedetomidine on postoperative mortality and morbidity: A systematic review and meta-analysis. Clin Ther. 2019;41(1):138–154.e4. https://doi.org/10.1016/j.clinthera.2018.10.022.

    Article  CAS  PubMed  Google Scholar 

  101. Pieri M, De Simone A, Rose S, De Domenico P, Lembo R, Denaro G, Landoni G, Monaco F. Trials focusing on prevention and treatment of delirium after cardiac surgery: A systematic review of randomized evidence. J Cardiothorac Vasc Anesth. 2020;34(6):1641–54. https://doi.org/10.1053/j.jvca.2019.09.028.

    Article  CAS  PubMed  Google Scholar 

  102. Berger M, Nadler JW, Browndyke J, Terrando N, Ponnusamy V, Cohen HJ, Whitson HE, Mathew JP. Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly. Anesthesiol Clin. 2015;33(3):517–50. https://doi.org/10.1016/j.anclin.2015.05.008.

    Article  PubMed  PubMed Central  Google Scholar 

  103. Moller JT, Cluitmans P, Rasmussen LS, Houx P, Rasmussen H, Canet J, Rabbitt P, Jolles J, Larsen K, Hanning CD, Langeron O, Johnson T, Lauven PM, Kristensen PA, Biedler A, van Beem H, Fraidakis O, Silverstein JH, Beneken JE, Gravenstein JS. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study. ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. Lancet (London, England). 1998;351(9106):857–61. https://doi.org/10.1016/s0140-6736(97)07382-0.

    Article  CAS  PubMed  Google Scholar 

  104. Xiao Q-X, Liu Q, Deng R, Gao Z-W, Zhang Y. Postoperative cognitive dysfunction in elderly patients undergoing hip arthroplasty. Psychogeriatrics. 2020; https://doi.org/10.1111/psyg.12516.

  105. ACE.

    Google Scholar 

  106. NICHE.

    Google Scholar 

  107. Ganz, D., Huang, C., & Saliba, D. (2013). Preventing falls in hospitals: A toolkit for improving quality of care 158(5), 390–396.

    Google Scholar 

  108. Abdelhamid A, Bunn D, Copley M, Cowap V, Dickinson A, Gray L, Howe A, Killett A, Lee J, Li F, Poland F, Potter J, Richardson K, Smithard D, Fox C, Hooper L. Effectiveness of interventions to directly support food and drink intake in people with dementia: Systematic review and meta-analysis. BMC Geriatr. 2016;16:26. https://doi.org/10.1186/s12877-016-0196-3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  109. Alagiakrishnan K, Bhanji RA, Kurian M. Evaluation and management of oropharyngeal dysphagia in different types of dementia: A systematic review. Arch Gerontol Geriatr. 2013;56(1):1–9. https://doi.org/10.1016/j.archger.2012.04.011.

    Article  PubMed  Google Scholar 

  110. Baijens LW, Clavé P, Cras P, Ekberg O, Forster A, Kolb GF, Leners J-C, Masiero S, Mateos-Nozal J, Ortega O, Smithard DG, Speyer R, Walshe M. European Society for Swallowing Disorders - European Union Geriatric Medicine Society white paper: Oropharyngeal dysphagia as a geriatric syndrome. Clin Interv Aging. 2016;11:1403–28. https://doi.org/10.2147/CIA.S107750.

    Article  PubMed  PubMed Central  Google Scholar 

  111. Flynn E, Smith CH, Walsh CD, Walshe M. Modifying the consistency of food and fluids for swallowing difficulties in dementia. The. Cochrane Database Syst Rev. 2018;2018(9) https://doi.org/10.1002/14651858.CD011077.pub2.

  112. Monitoring Hospital-Acquired Infections to Promote Patient Safety—United States, 1990–1999. (n.d.). Retrieved July 24, 2020, from https://www.cdc.gov/mmwr/preview/mmwrhtml/mm4908a1.htm

  113. Kort NP, Bemelmans Y, Vos R, Schotanus MGM. Low incidence of postoperative urinary retention with the use of a nurse-led bladder scan protocol after hip and knee arthroplasty: A retrospective cohort study. Eur J Orthop Surg Traumatol. 2018;28(2):283–9. https://doi.org/10.1007/s00590-017-2042-5.

    Article  CAS  PubMed  Google Scholar 

  114. Rosseland LA, Stubhaug A, Breivik H. Detecting postoperative urinary retention with an ultrasound scanner. Acta Anaesthesiol Scand. 2002;46(3):279–82. https://doi.org/10.1034/j.1399-6576.2002.t01-1-460309.x.

    Article  CAS  PubMed  Google Scholar 

  115. Bergstrom N, Braden BJ, Laguzza A, Holman V. The braden scale for predicting pressure sore risk. Nurs Res. 1987;36(4):205–10.

    Article  CAS  PubMed  Google Scholar 

  116. Defloor T, Grypdonck MFH. Pressure ulcers: Validation of two risk assessment scales. J Clin Nurs. 2005;14(3):373–82. https://doi.org/10.1111/j.1365-2702.2004.01058.x.

    Article  PubMed  Google Scholar 

  117. Lindgren M, Unosson M, Krantz A-M, Ek A-C. Pressure ulcer risk factors in patients undergoing surgery. J Adv Nurs. 2005;50(6):605–12. https://doi.org/10.1111/j.1365-2648.2005.03441.x.

    Article  PubMed  Google Scholar 

  118. Schultz A, Bien M, Dumond K, Brown K, Myers A. Etiology and incidence of pressure ulcers in surgical patients. AORN J. 1999;70(3):434, 437–440, 443–449. https://doi.org/10.1016/s0001-2092(06)62325-9.

    Article  CAS  PubMed  Google Scholar 

  119. Thorn CC, Smith M, Aziz O, Holme TC. The Waterlow score for risk assessment in surgical patients. Ann R Coll Surg Engl. 2013;95(1):52–6. https://doi.org/10.1308/003588413X13511609954770.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  120. American Society of Anesthesiologists Task Force on Acute Pain Management. Practice guidelines for acute pain management in the perioperative setting: An updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management. Anesthesiology. 2012;116(2):248–73. https://doi.org/10.1097/ALN.0b013e31823c1030.

    Article  Google Scholar 

  121. Kotzé A, Harris A, Baker C, Iqbal T, Lavies N, Richards T, Ryan K, Taylor C, Thomas D. British Committee for Standards in Haematology Guidelines on the Identification and Management of Pre-Operative Anaemia. Br J Haematol. 2015;171(3):322–31. https://doi.org/10.1111/bjh.13623.

    Article  PubMed  Google Scholar 

  122. Muñoz M, Acheson AG, Bisbe E, Butcher A, Gómez-Ramírez S, Khalafallah AA, Kehlet H, Kietaibl S, Liumbruno GM, Meybohm P, Rao Baikady R, Shander A, So-Osman C, Spahn DR, Klein AA. An international consensus statement on the management of postoperative anaemia after major surgical procedures. Anaesthesia. 2018;73(11):1418–31. https://doi.org/10.1111/anae.14358.

    Article  PubMed  PubMed Central  Google Scholar 

  123. Clark L, Robinson M, Varbanova M. Role of regional anesthesia in orthopedic trauma. Anesthesiol Clin. 2014;32(4):789–808. https://doi.org/10.1016/j.anclin.2014.08.002.

    Article  PubMed  Google Scholar 

  124. Liu S, Carpenter RL, Neal JM. Epidural anesthesia and analgesia. Their role in postoperative outcome. Anesthesiology. 1995;82(6):1474–506. https://doi.org/10.1097/00000542-199506000-00019.

    Article  CAS  PubMed  Google Scholar 

  125. Chan SP, Ip KY, Irwin MG. Peri-operative optimisation of elderly and frail patients: A narrative review. Anaesthesia. 2019;74(Suppl 1):80–9. https://doi.org/10.1111/anae.14512.

    Article  PubMed  Google Scholar 

  126. Parker MJ, Handoll HH, Griffiths R. Anaesthesia for hip fracture surgery in adults. Cochrane Database Syst Rev. 2001;4:CD000521. https://doi.org/10.1002/14651858.CD000521.

    Article  Google Scholar 

  127. Guay J, Choi P, Suresh S, Albert N, Kopp S, Pace NL. Neuraxial blockade for the prevention of postoperative mortality and major morbidity: An overview of Cochrane systematic reviews. The. Cochrane Database Syst Rev. 2014;1:CD010108. https://doi.org/10.1002/14651858.CD010108.pub2.

    Article  Google Scholar 

  128. Rodgers A, Walker N, Schug S, McKee A, Kehlet H, van Zundert A, Sage D, Futter M, Saville G, Clark T, MacMahon S. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: Results from overview of randomised trials. BMJ (Clinical Research Ed). 2000;321(7275):1493. https://doi.org/10.1136/bmj.321.7275.1493.

    Article  CAS  PubMed  Google Scholar 

  129. Neuman MD, Silber JH, Elkassabany NM, Ludwig JM, Fleisher LA. Comparative effectiveness of regional versus general anesthesia for hip fracture surgery in adults. Anesthesiology. 2012;117(1):72–92. https://doi.org/10.1097/ALN.0b013e3182545e7c.

    Article  CAS  PubMed  Google Scholar 

  130. Li T, Li J, Yuan L. Effect of regional vs general anesthesia on incidence of postoperative delirium in older patients undergoing hip fracture surgery: the RAGA randomized trial. JAMA. 2021 Dec;20

    Google Scholar 

  131. Li YW, Li HJ, Li HJ, Zhao BJ, Guo XY, Feng Y, et al. Delirium in older patients after combined epidural–general anesthesia or general anesthesia for major surgery: A randomized trial. Anesthesiology. 2021;

    Google Scholar 

  132. Yeager MP, Glass DD, Neff RK, Brinck-Johnsen T. Epidural anesthesia and analgesia in high-risk surgical patients. Anesthesiology. 1987;66(6):729–36. https://doi.org/10.1097/00000542-198706000-00004.

    Article  CAS  PubMed  Google Scholar 

  133. Matot I, Oppenheim-Eden A, Ratrot R, Baranova J, Davidson E, Eylon S, Peyser A, Liebergall M. Preoperative cardiac events in elderly patients with hip fracture randomized to epidural or conventional analgesia. Anesthesiology. 2003;98(1):156–63. https://doi.org/10.1097/00000542-200301000-00025.

    Article  PubMed  Google Scholar 

  134. Chen DX, Yang L, Ding L, Li SY, Qi YN, Li Q. Perioperative outcomes in geriatric patients undergoing hip fracture surgery with different anesthesia techniques: A systematic review and meta-analysis. Medicine. 2019;98(49):e18220. https://doi.org/10.1097/MD.0000000000018220.

    Article  PubMed  PubMed Central  Google Scholar 

  135. Soffin EM, Gibbons MM, Ko CY, Kates SL, Wick E, Cannesson M, Scott MJ, Wu CL. Evidence review conducted for the agency for healthcare research and quality safety program for improving surgical care and recovery: focus on anesthesiology for total knee arthroplasty. Anesth Analg. 2019;128(3):441–53. https://doi.org/10.1213/ANE.0000000000003564.

    Article  PubMed  Google Scholar 

  136. Maxwell L, White S. Anaesthetic management of patients with hip fractures: An update. Contin Educ Anaesth Crit Care Pain. 2013;13(5):179–83. https://doi.org/10.1093/bjaceaccp/mkt006.

    Article  Google Scholar 

  137. Beattie WS, Badner NH, Choi P. Epidural analgesia reduces postoperative myocardial infarction: A meta-analysis. Anesth Analg. 2001;93(4):853–8. https://doi.org/10.1097/00000539-200110000-00010.

    Article  CAS  PubMed  Google Scholar 

  138. Rawal N. Epidural technique for postoperative pain: Gold standard no more? Reg Anesth Pain Med. 2012;37(3):310–7. https://doi.org/10.1097/AAP.0b013e31825735c6.

    Article  PubMed  Google Scholar 

  139. Roy RC. Choosing general versus regional anesthesia for the elderly. Anesthesiol Clin North Am. 2000;18(1):91–104., vii. https://doi.org/10.1016/s0889-8537(05)70151-6.

    Article  CAS  PubMed  Google Scholar 

  140. Brindley PG. I. Improving teamwork in anaesthesia and critical care: Many lessons still to learn. Br J Anaesth. 2014;112(3):399–401. https://doi.org/10.1093/bja/aet334.

    Article  CAS  PubMed  Google Scholar 

  141. Brady M, Kinn S, Stuart P. Preoperative fasting for adults to prevent perioperative complications. The. Cochrane Database Syst Rev. 2003;4:CD004423. https://doi.org/10.1002/14651858.CD004423.

    Article  Google Scholar 

  142. Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery: A Review. JAMA Surg. 2017;152(3):292–8. https://doi.org/10.1001/jamasurg.2016.4952.

    Article  PubMed  Google Scholar 

  143. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective ProceduresAn Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration. Anesthesiol J Am Soc Anesthesiolog. 2017;126(3):376–93. https://doi.org/10.1097/ALN.0000000000001452.

    Article  Google Scholar 

  144. Black MK, Lupa MC, Lemley LW, Dreesen EB, Deaton AM III, RM. Things We Do for No Reason™: NPO After Midnight. J Hosp Med. 2021 Jun;16(6):368–70.

    PubMed  PubMed Central  Google Scholar 

  145. Cepeda MS, Farrar JT, Baumgarten M, Boston R, Carr DB, Strom BL. Side effects of opioids during short-term administration: Effect of age, gender, and race. Clin Pharmacol Ther. 2003;74(2):102–12. https://doi.org/10.1016/S0009-9236(03)00152-8.

    Article  CAS  PubMed  Google Scholar 

  146. Kehlet H, Dahl JB. Anaesthesia, surgery, and challenges in postoperative recovery. Lancet (London, England). 2003;362(9399):1921–8. https://doi.org/10.1016/S0140-6736(03)14966-5.

    Article  PubMed  Google Scholar 

  147. Moore RA, McQuay HJ. Prevalence of opioid adverse events in chronic non-malignant pain: Systematic review of randomised trials of oral opioids. Arthritis Res Ther. 2005;7(5):R1046–51. https://doi.org/10.1186/ar1782.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  148. Kruijt Spanjer MR, Bakker NA, Absalom AR. Pharmacology in the elderly and newer anaesthesia drugs. Best Pract Res Clin Anaesthesiol. 2011;25(3):355–65. https://doi.org/10.1016/j.bpa.2011.06.002.

    Article  CAS  PubMed  Google Scholar 

  149. Sinatra RS, Jahr JS, Reynolds LW, Viscusi ER, Groudine SB, Payen-Champenois C. Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery. Anesthesiology. 2005;102(4):822–31. https://doi.org/10.1097/00000542-200504000-00019.

    Article  CAS  PubMed  Google Scholar 

  150. Barbosa FT, Jucá MJ, Castro AA, Cavalcante JC. Neuraxial anaesthesia for lower-limb revascularization. Cochrane Database Syst Rev. 2013;7:CD007083. https://doi.org/10.1002/14651858.CD007083.pub3.

    Article  Google Scholar 

  151. Choi PT, Bhandari M, Scott J, Douketis J. Epidural analgesia for pain relief following hip or knee replacement. Cochrane Database Syst Rev. 2003;3:CD003071. https://doi.org/10.1002/14651858.CD003071.

    Article  Google Scholar 

  152. Jørgensen H, Wetterslev J, Møiniche S, Dahl JB. Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery. The. Cochrane Database Syst Rev. 2000;4:CD001893. https://doi.org/10.1002/14651858.CD001893.

    Article  Google Scholar 

  153. Joshi GP, Bonnet F, Shah R, Wilkinson RC, Camu F, Fischer B, Neugebauer EAM, Rawal N, Schug SA, Simanski C, Kehlet H. A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia. Anesth Analg. 2008;107(3):1026–40. https://doi.org/10.1213/01.ane.0000333274.63501.ff.

    Article  CAS  PubMed  Google Scholar 

  154. Neuman MD, Rosenbaum PR, Ludwig JM, Zubizarreta JR, Silber JH. Anesthesia technique, mortality, and length of stay after hip fracture surgery. JAMA. 2014;311(24):2508–17. https://doi.org/10.1001/jama.2014.6499.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  155. Nishimori M, Low JHS, Zheng H, Ballantyne JC. Epidural pain relief versus systemic opioid-based pain relief for abdominal aortic surgery. The. Cochrane Database Syst Rev. 2012;7:CD005059. https://doi.org/10.1002/14651858.CD005059.pub3.

    Article  Google Scholar 

  156. Paul JE, Arya A, Hurlburt L, Cheng J, Thabane L, Tidy A, Murthy Y. Femoral nerve block improves analgesia outcomes after total knee arthroplasty: A meta-analysis of randomized controlled trials. Anesthesiology. 2010;113(5):1144–62. https://doi.org/10.1097/ALN.0b013e3181f4b18.

    Article  PubMed  Google Scholar 

  157. Werawatganon T, Charuluxanun S. Patient controlled intravenous opioid analgesia versus continuous epidural analgesia for pain after intra-abdominal surgery. Cochrane Database Syst Rev. 2005;1:CD004088. https://doi.org/10.1002/14651858.CD004088.pub2.

    Article  Google Scholar 

  158. Gold BS, Kitz DS, Lecky JH, Neuhaus JM. Unanticipated admission to the hospital following ambulatory surgery. JAMA. 1989;262(21):3008–10. https://doi.org/10.1001/jama.1989.03430210050028.

    Article  CAS  PubMed  Google Scholar 

  159. Macario A, Weinger M, Carney S, Kim A. Which clinical anesthesia outcomes are important to avoid? The perspective of patients. Anesth Analg. 1999;89(3):652–8. https://doi.org/10.1097/00000539-199909000-00022.

    Article  CAS  PubMed  Google Scholar 

  160. Aronovitch SA. Intraoperatively acquired pressure ulcer prevalence: A national study. J Wound Ostomy Continence Nurs. 1999;26(3):130–6. https://doi.org/10.1016/s1071-5754(99)90030-x.

    Article  CAS  PubMed  Google Scholar 

  161. Aronovitch SA. Intraoperatively acquired pressure ulcers: Are there common risk factors? Ostomy Wound Manage. 2007;53(2):57–69.

    PubMed  Google Scholar 

  162. Nixon J, Cranny G, Bond S. Skin alterations of intact skin and risk factors associated with pressure ulcer development in surgical patients: A cohort study. Int J Nurs Stud. 2007;44(5):655–63. https://doi.org/10.1016/j.ijnurstu.2006.02.010.

    Article  PubMed  Google Scholar 

  163. Parks BJ. Postoperative peripheral neuropathies. Surgery. 1973;74(3):348–57.

    CAS  PubMed  Google Scholar 

  164. Rains DD, Rooke GA, Wahl CJ. Pathomechanisms and complications related to patient positioning and anesthesia during shoulder arthroscopy. Arthroscopy. 2011;27(4):532–41. https://doi.org/10.1016/j.arthro.2010.09.008.

    Article  PubMed  Google Scholar 

  165. LacKamp AN, Sieber FE. Physiologic response to anesthesia in the elderly. In: Rosenthal RA, Zenilman ME, Katlic MR, editors. Principles and practice of geriatric surgery. Springer; 2011. p. 291–303. https://doi.org/10.1007/978-1-4419-6999-6_24.

    Chapter  Google Scholar 

  166. Forbes SS, Eskicioglu C, Nathens AB, Fenech DS, Laflamme C, McLean RF, McLeod RS, Best Practice in General Surgery Committee, University of Toronto. Evidence-based guidelines for prevention of perioperative hypothermia. J Am Coll Surg. 2009;209(4):492–503.e1. https://doi.org/10.1016/j.jamcollsurg.2009.07.002.

    Article  PubMed  Google Scholar 

  167. Frank SM, Fleisher LA, Breslow MJ, Higgins MS, Olson KF, Kelly S, Beattie C. Perioperative maintenance of normothermia reduces the incidence of morbid cardiac events. A randomized clinical trial. JAMA. 1997;277(14):1127–34.

    Article  CAS  PubMed  Google Scholar 

  168. Grocott MPW, Dushianthan A, Hamilton MA, Mythen MG, Harrison D, Rowan K, Optimisation Systematic Review Steering Group. Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery. Cochrane Database Syst Rev. 2012;11:CD004082. https://doi.org/10.1002/14651858.CD004082.pub5.

    Article  PubMed  Google Scholar 

  169. Carson, Jeffrey L., et al. “Liberal or restrictive transfusion in high-risk patients after hip surgery.” N Engl J Med 365.26 (2011): 2453–2462.

    Google Scholar 

  170. March LM, Bagga H. Epidemiology of osteoarthritis in Australia. Med J Aust. 2004;180(S5):S6–10.

    Article  PubMed  Google Scholar 

  171. Pereira D, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E. The effect of osteoarthritis definition on prevalence and incidence estimates: A systematic review. Osteoarthr Cartil. 2011;19(11):1270–85. https://doi.org/10.1016/j.joca.2011.08.009.

    Article  CAS  Google Scholar 

  172. Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet (London, England). 2012;380(9859):2163–96. https://doi.org/10.1016/S0140-6736(12)61729-2.

    Article  PubMed  Google Scholar 

  173. Charlesworth J, Fitzpatrick J, Perera NKP, Orchard J. Osteoarthritis- a systematic review of long-term safety implications for osteoarthritis of the knee. BMC Musculoskelet Disord. 2019;20(1):151. https://doi.org/10.1186/s12891-019-2525-0.

    Article  PubMed  PubMed Central  Google Scholar 

  174. Lane NE, Brandt K, Hawker G, Peeva E, Schreyer E, Tsuji W, Hochberg MC. OARSI-FDA initiative: Defining the disease state of osteoarthritis. Osteoarthr Cartil. 2011;19(5):478–82. https://doi.org/10.1016/j.joca.2010.09.013.

    Article  CAS  Google Scholar 

  175. da Costa BR, Nüesch E, Kasteler R, Husni E, Welch V, Rutjes AWS, Jüni P. Oral or transdermal opioids for osteoarthritis of the knee or hip. Cochrane Database Syst Rev. 2014;9:CD003115. https://doi.org/10.1002/14651858.CD003115.pub4.

    Article  Google Scholar 

  176. Fuggle N, Curtis E, Shaw S, Spooner L, Bruyère O, Ntani G, Parsons C, Conaghan PG, Corp N, Honvo G, Uebelhart D, Baird J, Dennison E, Reginster J-Y, Cooper C. Safety of opioids in osteoarthritis: Outcomes of a systematic review and meta-analysis. Drugs Aging. 2019;36(Suppl 1):129–43. https://doi.org/10.1007/s40266-019-00666-9.

    Article  PubMed  PubMed Central  Google Scholar 

  177. Brandes M, Ringling M, Winter C, Hillmann A, Rosenbaum D. Changes in physical activity and health-related quality of life during the first year after total knee arthroplasty. Arthritis Care Res. 2011;63(3):328–34. https://doi.org/10.1002/acr.20384.

    Article  Google Scholar 

  178. Ethgen O, Bruyère O, Richy F, Dardennes C, Reginster J-Y. Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature. J Bone Joint Surg Am. 2004;86(5):963–74. https://doi.org/10.2106/00004623-200405000-00012.

    Article  PubMed  Google Scholar 

  179. Jones CA, Pohar S. Health-related quality of life after total joint arthroplasty: A scoping review. Clin Geriatr Med. 2012;28(3):395–429. https://doi.org/10.1016/j.cger.2012.06.001.

    Article  PubMed  Google Scholar 

  180. Peter WF, Dekker J, Tilbury C, Tordoir RL, Verdegaal SHM, Onstenk R, Bénard MR, Vehmeijer SB, Fiocco M, Vermeulen HM, van der Linden-van der Zwaag HMJ, Nelissen RGHH, Vliet Vlieland TPM. The association between comorbidities and pain, physical function and quality of life following hip and knee arthroplasty. Rheumatol Int. 2015;35(7):1233–41. https://doi.org/10.1007/s00296-015-3211-7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  181. Westby MD, Brittain A, Backman CL. Expert consensus on best practices for post-acute rehabilitation after total hip and knee arthroplasty: A Canada and United States Delphi study. Arthritis Care Res. 2014;66(3):411–23. https://doi.org/10.1002/acr.22164.

    Article  Google Scholar 

  182. Schwartz AM, Farley KX, Guild GN, Bradbury TL. Projections and epidemiology of revision hip and knee arthroplasty in the United States to 2030. J Arthroplast. 2020;35(6S):S79–85. https://doi.org/10.1016/j.arth.2020.02.030.

    Article  Google Scholar 

  183. Sloan M, Premkumar A, Sheth NP. Projected volume of primary total joint arthroplasty in the U.S., 2014 to 2030. J Bone Joint Surg Am. 2018;100(17):1455–60. https://doi.org/10.2106/JBJS.17.01617.

    Article  PubMed  Google Scholar 

  184. Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007;89(4):780–5. https://doi.org/10.2106/JBJS.F.00222.

    Article  PubMed  Google Scholar 

  185. Maradit Kremers H, Larson DR, Crowson CS, Kremers WK, Washington RE, Steiner CA, Jiranek WA, Berry DJ. Prevalence of total hip and knee replacement in the United States. J Bone Joint Surg Am. 2015;97(17):1386–97. https://doi.org/10.2106/JBJS.N.01141.

    Article  PubMed  Google Scholar 

  186. Coventry MB, Beckenbaugh RD, Nolan DR, Ilstrup DM. 2012 total hip arthroplasties. A study of postoperative course and early complications. J Bone Joint Surg Am. 1974;56(2):273–84.

    Article  CAS  PubMed  Google Scholar 

  187. Horstmann WG, Swierstra MJ, Ohanis D, Castelein RM, Kollen BJ, Verheyen CCPM. Reduction of blood loss with the use of a new combined intra-operative and post-operative autologous blood transfusion system compared with no drainage in primary total hip replacement. Bone Joint J. 2013;95-B(5):616–22. https://doi.org/10.1302/0301-620X.95B5.30472.

    Article  CAS  PubMed  Google Scholar 

  188. Jameson SS, Khan SK, Baker P, James P, Gray A, Reed MR, Deehan DJ. A national analysis of complications following hemiarthroplasty for hip fracture in older patients. QJM. 2012;105(5):455–60. https://doi.org/10.1093/qjmed/hcs004.

    Article  CAS  PubMed  Google Scholar 

  189. Regenbogen SE, Cain-Nielsen AH, Norton EC, Chen LM, Birkmeyer JD, Skinner JS. Costs and consequences of early hospital discharge after major inpatient surgery in older adults. JAMA Surg. 2017;152(5):e170123. https://doi.org/10.1001/jamasurg.2017.0123.

    Article  PubMed  PubMed Central  Google Scholar 

  190. Sharrock NE, Beksac B, Flynn E, Go G, Della Valle AG. Hypotensive epidural anaesthesia in patients with preoperative renal dysfunction undergoing total hip replacement. Br J Anaesth. 2006;96(2):207–12. https://doi.org/10.1093/bja/aei308.

    Article  CAS  PubMed  Google Scholar 

  191. Wilson JM, Schwartz AM, Farley KX, Bradbury TL, Guild GN. Combined malnutrition and frailty significantly increases complications and mortality in patients undergoing elective total hip arthroplasty. J Arthroplast. 2020;0(0) https://doi.org/10.1016/j.arth.2020.04.028.

  192. Sherman AE, Plantz MA, Hardt KD. Outcomes of Elective Total Hip Arthroplasty in Nonagenarians and Centenarians. J Arthroplast. 2020; https://doi.org/10.1016/j.arth.2020.03.026.

  193. Katz BP, Freund DA, Heck DA, Dittus RS, Paul JE, Wright J, Coyte P, Holleman E, Hawker G. Demographic variation in the rate of knee replacement: A multi-year analysis. Health Serv Res. 1996;31(2):125–40.

    CAS  PubMed  PubMed Central  Google Scholar 

  194. Baker PN, van der Meulen JH, Lewsey J, Gregg PJ, National Joint Registry for England and Wales. The role of pain and function in determining patient satisfaction after total knee replacement. Data from the National Joint Registry for England and Wales. J Bone Joint Surg. 2007;89(7):893–900. https://doi.org/10.1302/0301-620X.89B7.19091.

    Article  CAS  Google Scholar 

  195. Kane RL, Saleh KJ, Wilt TJ, Bershadsky B. The functional outcomes of total knee arthroplasty. J Bone Joint Surg Am. 2005;87(8):1719–24. https://doi.org/10.2106/JBJS.D.02714.

    Article  PubMed  Google Scholar 

  196. Kuperman EF, Schweizer M, Joy P, Gu X, Fang MM. The effects of advanced age on primary total knee arthroplasty: A meta-analysis and systematic review. BMC Geriatr. 2016;16:41. https://doi.org/10.1186/s12877-016-0215-4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  197. Skou ST, Roos EM, Laursen MB, Rathleff MS, Arendt-Nielsen L, Simonsen O, Rasmussen S. A randomized, controlled trial of total knee replacement. N Engl J Med. 2015;373(17):1597–606. https://doi.org/10.1056/NEJMoa1505467.

    Article  CAS  PubMed  Google Scholar 

  198. Hamel MB, Toth M, Legedza A, Rosen MP. Joint replacement surgery in elderly patients with severe osteoarthritis of the hip or knee: Decision making, postoperative recovery, and clinical outcomes. Arch Intern Med. 2008;168(13):1430–40. https://doi.org/10.1001/archinte.168.13.1430.

    Article  PubMed  Google Scholar 

  199. Adie S, Harris I, Chuan A, Lewis P, Naylor JM. Selecting and optimising patients for total knee arthroplasty. Med J Aust. 2019;210(3):135–41. https://doi.org/10.5694/mja2.12109.

    Article  PubMed  Google Scholar 

  200. Shah A, Memon M, Kay J, Wood TJ, Tushinski DM, Khanna V, McMaster Arthroplasty Collective (MAC) group. Preoperative patient factors affecting length of stay following total knee arthroplasty: A systematic review and meta-analysis. J Arthroplast. 2019;34(9):2124–2165.e1. https://doi.org/10.1016/j.arth.2019.04.048.

    Article  Google Scholar 

  201. Singh JA, Lewallen DG. Are outcomes after total knee arthroplasty worsening over time? A time-trends study of activity limitation and pain outcomes. BMC Musculoskelet Disord. 2014;15 https://doi.org/10.1186/1471-2474-15-440.

  202. Canovas F, Dagneaux L. Quality of life after total knee arthroplasty. Orthop Traumatol Surg Res. 2018;104(1S):S41–6. https://doi.org/10.1016/j.otsr.2017.04.017.

    Article  CAS  PubMed  Google Scholar 

  203. Bayliss LE, Culliford D, Monk AP, Glyn-Jones S, Prieto-Alhambra D, Judge A, Cooper C, Carr AJ, Arden NK, Beard DJ, Price AJ. The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: A population-based cohort study. Lancet (London, England). 2017;389(10077):1424–30. https://doi.org/10.1016/S0140-6736(17)30059-4.

    Article  PubMed  Google Scholar 

  204. Ellis G, Gardner M, Tsiachristas A, Langhorne P, Burke O, Harwood RH, Conroy SP, Kircher T, Somme D, Saltvedt I, Wald H, O’Neill D, Robinson D, Shepperd S. Comprehensive geriatric assessment for older adults admitted to hospital. Cochrane Database Syst Rev. 2017;9:CD006211. https://doi.org/10.1002/14651858.CD006211.pub3.

    Article  PubMed  Google Scholar 

  205. Scanlan BC. The value of comprehensive geriatric assessment. Care Manag J. 2005;6(1):2–8. https://doi.org/10.1891/cmaj.2005.6.1.2.

    Article  PubMed  Google Scholar 

  206. Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: A meta-analysis of controlled trials. Lancet (London, England). 1993;342(8878):1032–6. https://doi.org/10.1016/0140-6736(93)92884-v.

    Article  CAS  PubMed  Google Scholar 

  207. Enhanced recovery. (2017, October 18).. Nhs.Uk. https://www.nhs.uk/conditions/enhanced-recovery/

    Google Scholar 

  208. Wainwright TW, Gill M, McDonald DA, Middleton RG, Reed M, Sahota O, Yates P, Ljungqvist O. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Acta Orthop. 2020;91(1):3–19. https://doi.org/10.1080/17453674.2019.1683790.

    Article  PubMed  Google Scholar 

  209. Mont MA, Jacobs JJ, Boggio LN, Bozic KJ, Della Valle CJ, Goodman SB, Lewis CG, Yates AJJ, Watters WCI, Turkelson CM, Wies JL, Donnelly P, Patel N, Sluka P. Preventing venous thromboembolic disease in patients undergoing elective hip and knee arthroplasty. J Am Acad Orthop Surg. 2011;19(12):768–76.

    Article  PubMed  Google Scholar 

  210. Tedesco D, Gori D, Desai KR, Asch S, Carroll IR, Curtin C, McDonald KM, Fantini MP, Hernandez-Boussard T. Drug-free interventions to reduce pain or opioid consumption after total knee arthroplasty: A systematic review and meta-analysis. JAMA Surg. 2017;152(10):–e172872. https://doi.org/10.1001/jamasurg.2017.2872.

  211. Husted H, Lunn TH, Troelsen A, Gaarn-Larsen L, Kristensen BB, Kehlet H. Why still in hospital after fast-track hip and knee arthroplasty? Acta Orthop. 2011;82(6):679–84. https://doi.org/10.3109/17453674.2011.636682.

    Article  PubMed  PubMed Central  Google Scholar 

  212. Malviya A, Martin K, Harper I, Muller SD, Emmerson KP, Partington PF, Reed MR. Enhanced recovery program for hip and knee replacement reduces death rate. Acta Orthop. 2011;82(5):577–81. https://doi.org/10.3109/17453674.2011.618911.

    Article  PubMed  PubMed Central  Google Scholar 

  213. McDonald DA, Siegmeth R, Deakin AH, Kinninmonth AWG, Scott NB. An enhanced recovery programme for primary total knee arthroplasty in the United Kingdom—Follow up at one year. Knee. 2012;19(5):525–9. https://doi.org/10.1016/j.knee.2011.07.012.

    Article  CAS  PubMed  Google Scholar 

  214. Raphael M, Jaeger M, van Vlymen J. Easily adoptable total joint arthroplasty program allows discharge home in two days. Canadian J Anaesth. 2011;58(10):902–10. https://doi.org/10.1007/s12630-011-9565-8.

    Article  Google Scholar 

  215. Berg U, BüLow E, Sundberg M, Rolfson O. No increase in readmissions or adverse events after implementation of fast-track program in total hip and knee replacement at 8 Swedish hospitals: An observational before-and-after study of 14,148 total joint replacements 2011–2015. Acta Orthop. 2018;89(5):522–7. https://doi.org/10.1080/17453674.2018.1492507.

    Article  PubMed  PubMed Central  Google Scholar 

  216. Kehlet H. Fast-track hip and knee arthroplasty. Lancet (London, England). 2013;381(9878):1600–2. https://doi.org/10.1016/S0140-6736(13)61003-X.

    Article  PubMed  Google Scholar 

  217. Khan SK, Malviya A, Muller SD, Carluke I, Partington PF, Emmerson KP, Reed MR. Reduced short-term complications and mortality following Enhanced Recovery primary hip and knee arthroplasty: Results from 6000 consecutive procedures. Acta Orthop. 2014;85(1):26–31. https://doi.org/10.3109/17453674.2013.874925.

    Article  PubMed  PubMed Central  Google Scholar 

  218. Petersen PB, Kehlet H, Jørgensen CC. Myocardial infarction following fast-track total hip and knee arthroplasty—incidence, time course, and risk factors: A prospective cohort study of 24,862 procedures. Acta Orthop. 2018;89(6):603–9. https://doi.org/10.1080/17453674.2018.1517487.

    Article  PubMed  PubMed Central  Google Scholar 

  219. Aasvang EK, Luna IE, Kehlet H. Challenges in postdischarge function and recovery: The case of fast-track hip and knee arthroplasty. Br J Anaesth. 2015;115(6):861–6. https://doi.org/10.1093/bja/aev257.

    Article  CAS  PubMed  Google Scholar 

  220. den Hartog YM, Mathijssen NM, Vehmeijer SB. Reduced length of hospital stay after the introduction of a rapid recovery protocol for primary THA procedures. Acta Orthop. 2013;84(5):444–7. https://doi.org/10.3109/17453674.2013.838657.

    Article  Google Scholar 

  221. Gromov K, Kjærsgaard-Andersen P, Revald P, Kehlet H, Husted H. Feasibility of outpatient total hip and knee arthroplasty in unselected patients. Acta Orthop. 2017;88(5):516–21. https://doi.org/10.1080/17453674.2017.1314158.

    Article  PubMed  PubMed Central  Google Scholar 

  222. Hansen TB, Bredtoft HK, Larsen K. Preoperative physical optimization in fast-track hip and knee arthroplasty. Dan Med J. 2012;59(2):A4381.

    PubMed  Google Scholar 

  223. Bergin C, Speroni KG, Travis T, Bergin J, Sheridan MJ, Kelly K, Daniel MG. Effect of preoperative incentive spirometry patient education on patient outcomes in the knee and hip joint replacement population. J Perianes Nurs. 2014;29(1):20–7. https://doi.org/10.1016/j.jopan.2013.01.009.

    Article  Google Scholar 

  224. Jordan RW, Smith NA, Chahal GS, Casson C, Reed MR, Sprowson AP. Enhanced education and physiotherapy before knee replacement; is it worth it? A systematic review. Physiotherapy. 2014;100(4):305–12. https://doi.org/10.1016/j.physio.2014.03.003.

    Article  CAS  PubMed  Google Scholar 

  225. Louw A, Diener I, Butler DS, Puentedura EJ. Preoperative education addressing postoperative pain in total joint arthroplasty: Review of content and educational delivery methods. Physiother Theory Pract. 2013;29(3):175–94. https://doi.org/10.3109/09593985.2012.727527.

    Article  PubMed  Google Scholar 

  226. Huddleston JM, Long KH, Naessens JM, Vanness D, Larson D, Trousdale R, Plevak M, Cabanela M, Ilstrup D, Wachter RM, Hospitalist-Orthopedic Team Trial Investigators. Medical and surgical comanagement after elective hip and knee arthroplasty: A randomized, controlled trial. Ann Intern Med. 2004;141(1):28–38. https://doi.org/10.7326/0003-4819-141-1-200407060-00012.

    Article  PubMed  Google Scholar 

  227. Stevens, J. A., & Burns, E. (2015). A CDC compendium of effective fall interventions: What works for community-dwelling older adults.

    Google Scholar 

  228. Lyles CR, Schafer AL, Seligman HK. Income, food insecurity, and osteoporosis among older adults in the 2007–2008 National Health and Nutrition Examination Survey (NHANES). J Health Care Poor Underserved. 2014;25(4):1530–41. https://doi.org/10.1353/hpu.2014.0174.

    Article  PubMed  Google Scholar 

  229. Castronuovo E, Pezzotti P, Franzo A, Di Lallo D, Guasticchi G. Early and late mortality in elderly patients after hip fracture: A cohort study using administrative health databases in the Lazio region, Italy. BMC Geriatr. 2011;11:37. https://doi.org/10.1186/1471-2318-11-37.

    Article  PubMed  PubMed Central  Google Scholar 

  230. HCUP Databases. (2016). Healthcare Cost and Utilization Project (HCUP). http://www.ahrq.gov/data/hcup/index.html

    Google Scholar 

  231. Hip Fractures Among Older Adults | Home and Recreational Safety | CDC Injury Center. (2019, May 2). https://www.cdc.gov/homeandrecreationalsafety/falls/adulthipfx.html

  232. Kristensen MT, Kehlet H. The basic mobility status upon acute hospital discharge is an independent risk factor for mortality up to 5 years after hip fracture surgery. Acta Orthop. 2018;89(1):47–52. https://doi.org/10.1080/17453674.2017.1382038.

    Article  PubMed  Google Scholar 

  233. Radosavljevic N, Nikolic D, Lazovic M, Jeremic A. Hip fractures in a geriatric population—rehabilitation based on patients needs. Aging Dis. 2014;5(3):177–82. https://doi.org/10.14336/AD.2014.0500177.

    Article  PubMed  PubMed Central  Google Scholar 

  234. Magaziner J, Hawkes W, Hebel JR, Zimmerman SI, Fox KM, Dolan M, Felsenthal G, Kenzora J. Recovery from hip fracture in eight areas of function. J Gerontol A Biol Sci Med Sci. 2000;55(9):M498–507. https://doi.org/10.1093/gerona/55.9.m498.

    Article  CAS  PubMed  Google Scholar 

  235. Panula J, Pihlajamäki H, Mattila VM, Jaatinen P, Vahlberg T, Aarnio P, Kivelä S-L. Mortality and cause of death in hip fracture patients aged 65 or older: A population-based study. BMC Musculoskelet Disord. 2011;12:105. https://doi.org/10.1186/1471-2474-12-105.

    Article  PubMed  PubMed Central  Google Scholar 

  236. Schnell S, Friedman SM, Mendelson DA, Bingham KW, Kates SL. The 1-year mortality of patients treated in a hip fracture program for elders. Geriatr Orthop Surg Rehabil. 2010;1(1):6–14. https://doi.org/10.1177/2151458510378105.

    Article  PubMed  PubMed Central  Google Scholar 

  237. Kates SL, Blake D, Bingham KW, Kates OS, Mendelson DA, Friedman SM. Comparison of an organized geriatric fracture program to United States Government Data. Geriatr Orthop Surg Rehabil. 2010;1(1):15–21. https://doi.org/10.1177/2151458510382231.

    Article  PubMed  PubMed Central  Google Scholar 

  238. Al-Ani AN, Samuelsson B, Tidermark J, Norling A, Ekström W, Cederholm T, Hedström M. Early operation on patients with a hip fracture improved the ability to return to independent living. A prospective study of 850 patients. J Bone Joint Surg Am. 2008;90(7):1436–42. https://doi.org/10.2106/JBJS.G.00890.

    Article  PubMed  Google Scholar 

  239. Belmont PJ, Garcia EJ, Romano D, Bader JO, Nelson KJ, Schoenfeld AJ. Risk factors for complications and in-hospital mortality following hip fractures: A study using the National Trauma Data Bank. Arch Orthop Trauma Surg. 2014;134(5):597–604. https://doi.org/10.1007/s00402-014-1959-y.

    Article  PubMed  Google Scholar 

  240. Bernstein J, Roberts FO, Wiesel BB, Ahn J. Preoperative testing for hip fracture patients delays surgery, prolongs hospital stays, and rarely dictates care. J Orthop Trauma. 2016;30(2):78–80. https://doi.org/10.1097/BOT.0000000000000444.

    Article  PubMed  Google Scholar 

  241. Bottle A, Aylin P. Mortality associated with delay in operation after hip fracture: Observational study. Br Med J. 2006;332(7547):947–51. https://doi.org/10.1136/bmj.38790.468519.55.

    Article  Google Scholar 

  242. Krause, B. (2014). Management of hip fractures in the elderly: Evidence-based clinical practice guideline. 79.

    Google Scholar 

  243. Mutlu H, Bilgili F, Mutlu S, Karaman O, Cakal B, Ozkaya U. The effects of preoperative non-invasive cardiac tests on delay to surgery and subsequent mortality in elderly patients with hip fracture. J Back Musculoskelet Rehabil. 2016;29(1):49–54. https://doi.org/10.3233/BMR-150595.

    Article  PubMed  Google Scholar 

  244. Berry SD, Rothbaum RR, Kiel DP, Lee Y, Mitchell SL. Association of Clinical Outcomes With Surgical Repair of Hip Fracture vs Nonsurgical Management in Nursing Home Residents With Advanced Dementia. JAMA Intern Med. 2018;178(6):774–80. https://doi.org/10.1001/jamainternmed.2018.0743.

    Article  PubMed  PubMed Central  Google Scholar 

  245. Blauth M, Kates SL, Nicholas JA. Osteoporotic Fracture Care: Medical and Surgical Management. Thieme; 2018.

    Google Scholar 

  246. Grigoryan KV, Javedan H, Rudolph JL. Orthogeriatric care models and outcomes in hip fracture patients: A systematic review and meta-analysis. J Orthop Trauma. 2014;28(3):e49–55. https://doi.org/10.1097/BOT.0b013e3182a5a045.

    Article  PubMed  PubMed Central  Google Scholar 

  247. Moyet J, Deschasse G, Marquant B, Mertl P, Bloch F. Which is the optimal orthogeriatric care model to prevent mortality of elderly subjects post hip fractures? A systematic review and meta-analysis based on current clinical practice. Int Orthop. 2019;43(6):1449–54. https://doi.org/10.1007/s00264-018-3928-5.

    Article  CAS  PubMed  Google Scholar 

  248. Prestmo A, Hagen G, Sletvold O, Helbostad JL, Thingstad P, Taraldsen K, Lydersen S, Halsteinli V, Saltnes T, Lamb SE, Johnsen LG, Saltvedt I. Comprehensive geriatric care for patients with hip fractures: A prospective, randomised, controlled trial. Lancet (London, England). 2015;385(9978):1623–33. https://doi.org/10.1016/S0140-6736(14)62409-0.

    Article  PubMed  Google Scholar 

  249. Roche JJW, Wenn RT, Sahota O, Moran CG. Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: Prospective observational cohort study. BMJ (Clinical Research Ed). 2005;331(7529):1374. https://doi.org/10.1136/bmj.38643.663843.55.

    Article  CAS  PubMed  Google Scholar 

  250. Soong C, Cram P, Chezar K, Tajammal F, Exconde K, Matelski J, Sinha SK, Abrams HB, Fan-Lun C, Fabbruzzo-Cota C, Backstein D, Bell CM. Impact of an Integrated Hip Fracture Inpatient Program on Length of Stay and Costs. J Orthop Trauma. 2016;30(12):647–52. https://doi.org/10.1097/BOT.0000000000000691.

    Article  PubMed  Google Scholar 

  251. Vidán M, Serra JA, Moreno C, Riquelme G, Ortiz J. Efficacy of a comprehensive geriatric intervention in older patients hospitalized for hip fracture: A randomized, controlled trial. J Am Geriatr Soc. 2005;53(9):1476–82. https://doi.org/10.1111/j.1532-5415.2005.53466.x.

    Article  PubMed  Google Scholar 

  252. Baroni M, Serra R, Boccardi V, Ercolani S, Zengarini E, Casucci P, Valecchi R, Rinonapoli G, Caraffa A, Mecocci P, Ruggiero C. The orthogeriatric comanagement improves clinical outcomes of hip fracture in older adults. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2019;30(4):907–16. https://doi.org/10.1007/s00198-019-04858-2.

    Article  CAS  PubMed  Google Scholar 

  253. Forni S, Pieralli F, Sergi A, Lorini C, Bonaccorsi G, Vannucci A. Mortality after hip fracture in the elderly: The role of a multidisciplinary approach and time to surgery in a retrospective observational study on 23,973 patients. Arch Gerontol Geriatr. 2016;66:13–7. https://doi.org/10.1016/j.archger.2016.04.014.

    Article  PubMed  Google Scholar 

  254. Hempsall, V. J., Robertson, D. R., Campbell, M. J., & Briggs, R. S. (1990). Orthopaedic geriatric care--is it effective? A prospective population-based comparison of outcome in fractured neck of femur. J R Coll Physicians Lond, 24(1), 47–50.

    Google Scholar 

  255. Leal J, Gray AM, Hawley S, Prieto-Alhambra D, Delmestri A, Arden NK, Cooper C, Javaid MK, Judge A, and the REFReSH Study Group. Cost-effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: A population-based study. J Bone Miner Res Off J Am Soc Bone Miner Res. 2017;32(2):203–11. https://doi.org/10.1002/jbmr.2995.

    Article  Google Scholar 

  256. Patel JN, Klein DS, Sreekumar S, Liporace FA, Yoon RS. Outcomes in multidisciplinary team-based approach in geriatric hip fracture care: A systematic review. J Am Acad Orthop Surg. 2020;28(3):128–33. https://doi.org/10.5435/JAAOS-D-18-00425.

    Article  PubMed  Google Scholar 

  257. Sabharwal S, Wilson H. Orthogeriatrics in the management of frail older patients with a fragility fracture. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2015;26(10):2387–99. https://doi.org/10.1007/s00198-015-3166-2.

    Article  CAS  PubMed  Google Scholar 

  258. Van Grootven B, Mendelson DA, Deschodt M. Impact of geriatric co-management programmes on outcomes in older surgical patients: Update of recent evidence. Curr Opin Anaesthesiol. 2020;33(1):114–21. https://doi.org/10.1097/ACO.0000000000000815.

    Article  PubMed  Google Scholar 

  259. Maxwell BG, Mirza A. Medical comanagement of hip fracture patients is not associated with superior perioperative outcomes: A propensity score-matched retrospective cohort analysis of the national surgical quality improvement project. J Hosp Med. 2019;14:E1–7. https://doi.org/10.12788/jhm.3343.

    Article  Google Scholar 

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Authors and Affiliations

  1. Division of Hospital Medicine, Department of Medicine, Zucker School of Medicine at Hofstra Northwell, Manhasset, NY, USA

    Liron Sinvani

  2. Vice President of Medical Services and Chief Medical Officer, Jewish Senior Life, Rochester, NY, USA

    Daniel Ari Mendelson

Authors
  1. Liron Sinvani
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  2. Daniel Ari Mendelson
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Correspondence to Liron Sinvani .

Editor information

Editors and Affiliations

  1. California Association of Long Term Care Medicine, Newbury Park, CA, USA

    Michael R. Wasserman

  2. Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA, USA

    Debra Bakerjian

  3. Department of Clinical Pharmacy, University of Colorado School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA

    Sunny Linnebur

  4. Division of Geriatrics, SUNY Upstate Medical University, Syracuse, NY, USA

    Sharon Brangman

  5. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Matteo Cesari

  6. Section of Geriatric Medicine, Division of Internal Medicine, Department of Medicine, Cedars-Sinai, Beverly Hills, CA, USA

    Sonja Rosen

Section Editor information

  1. Betty Irene Moore School of Nursing, University of California, Davis, Sacramento, CA, USA

    Deb Bakerjian PhD, APRN, FAAN, FAANP

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Sinvani, L., Mendelson, D.A. (2023). Surgical Care. In: Wasserman, M.R., Bakerjian, D., Linnebur, S., Brangman, S., Cesari, M., Rosen, S. (eds) Geriatric Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-01782-8_15-1

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  • DOI: https://doi.org/10.1007/978-3-030-01782-8_15-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-01782-8

  • Online ISBN: 978-3-030-01782-8

  • eBook Packages: Springer Reference MedicineReference Module Medicine

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